E-cigarettes an evidence update A report commissioned by Public Health England

E-cigarettes: an evidence update details (including quantification) on all the ingredients contained in, andemissions resulting from the use of, the product, by brand name toxicological data regarding ingredients and emissions, including when heated,with reference particularly to health of consumers when inhaled including anyaddictive effect information on nicotine doses and uptake when consumed under normal orreasonably foreseeable conditions description of the product components, including where appropriate openingand refill mechanisms of product or refill containers description of the production process and declaration that it conforms with theTPD declaration that manufacturer/importer bear full responsibility for the quality andsafety of the product when placed on market and used under normal orreasonably foreseeable conditionsnicotine-containing liquid restrictions: EC must not contain more than 20 mg/ml of nicotine nicotine-containing liquid must be in dedicated refill containers not exceeding10ml volume, and cartridges or tanks do not exceed a volume of 2ml additives are not prohibited but the nicotine-containing liquids cannot containadditives that are otherwise prohibited by the other Articles in the TPD high purity ingredients must be used and substances other than those declaredshould only be present in trace quantities which are unavoidable duringmanufacture ingredients must not pose a risk to health either when heated or not heated nicotine doses must be delivered at consistent levels under normal conditions ofuseproducts are required to be child and tamper proof, protected against breakage andleakage and have a mechanism that ensures refilling without leakageproducts must include a leaflet with information on: instructions for use and storage of the product, including a reference that theproduct is not recommended for use by young people and non-smokers contra-indications warnings for specific groups possible adverse effects addictiveness and toxicity contact details of manufacturer/importer and a legal or natural contact personwithin the EUoutside packaging of products must include: list of all ingredients contained in the product in descending order of the weight an indication of the nicotine content and delivery per dose batch number recommendation to keep the product out of reach of children21