Challenges of Regulation and Risk Assessment of Nanomaterials

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03. Integrating testing strategies for ecotoxicity assessment [K. Hund-Rinke, Fraunhofer-IME] 04. Ageing and toxicity of real NM in aquatic environment [J. Rose, CEREGE] 05. Comparing the reproductive toxicity of ZnO nanoparticles, bulk ZnO, and ZnCl2 to the earthworm Eisenia Andrei [D. Spurgeon, CEH] 06. The bioavailability and trophic transfer of manufactured nanomaterials in aquatic and terrestrial food webs: Research challenges and potential risks [P. M. Bertsch, University of Kentucky, USA] 07. Aquatic Toxicity in Fish: Chronic Studies, Sub-lethal Effects [T. Henry, University of Plymouth] PODIUM DISCUSSION* 6 TH SESSION: HUMAN TOXICITY CHAIR: L. TRAN (IOM) 3 RD DAY 09:00 – 14:00 01. Introduction: content and goal of the session 02. Challenges in nanomaterials human health risk assessment [K. Aschberger, JRC] 03. Exploring the genotoxic potential of engineered nanomaterials [L. Gonzalez, Vrije Universiteit Brussel] 04. Variation in acute toxicity for 9 engineered nanoparticles in murine lungs [I. Gosens, RIVM] 05. Assessing the toxicological impact of a panel of engineered nanomaterials for risk assessment purposes [V. Stone, Heriot-Watt University] 06. Biokinetics of manufactured nanomaterials in vivo [W. Kreyling, Helmholtz Zentrum] PODIUM DISCUSSION* CONCLUSIONS Take-home messages and closing [L. Tran, IOM] * Podium discussion: guided by chair and speakers, with the active participation of the audience. 66
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Challenges of Regulation and Risk A
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TABLE OF CONTENTS 1. INTRODUCTION .
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2. REGULATORY DEVELOPMENTS 2.1. Sum
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into risk assessments and risk mana
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Nanomaterials in the Regulatory Dev
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Guidance on the risk assessment of
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Current Progress of activity and ef
Page 15 and 16: of the Sponsorship programme and pr
Page 17 and 18: exposure using new metrics and to d
Page 19 and 20: and risks would increase the probab
Page 21 and 22: OECD Working Party on Manufactured
Page 23 and 24: REACH Implementation Project on Nan
Page 25 and 26: Industry experience with conducting
Page 27 and 28: Health, Safety, and Environment: As
Page 29 and 30: 4. CHARACTERISATION AND DETECTION O
Page 31 and 32: 4.2. Abstracts 31
Page 33 and 34: Primary and secondary characterizat
Page 35 and 36: 5. EXPOSURE ASSESSMENT 5.1. Summary
Page 39 and 40: Application and adaptation of expos
Page 41 and 42: areas. The final remark was that th
Page 45 and 46: Integrating test strategy for ecoto
Page 47 and 48: Ageing and Toxicity of real NM in a
Page 49 and 50: The bioavailability and trophic tra
Page 51 and 52: 7. HUMAN TOXICITY 7.1. Summary reco
Page 55 and 56: Variation in acute toxicity for 9 e
Page 57 and 58: In conclusion, the in vitro hepatoc
Page 59 and 60: Acknowledgements The editors would
Page 61 and 62: 24 FURUNO Shoko Association (NIA) A
Page 63 and 64: 76 VOM BROCKE Jochen German Federal
Page 65: 05. NANEX: development of Exposure
Page 69 and 70: How to obtain EU publications Our p
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