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scientific program - World Allergy Organization

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Imagine research targeting IgE, a key component of the<br />

immune mechanism underlying allergic asthma, 1 to better<br />

understand its role in the disease<br />

Imagine pursuing strategies to interrupt the allergicinflammatory<br />

cascade before inflammatory mediators<br />

are released to do their damage 1,2<br />

Imagine understanding why many asthma patients remain<br />

suboptimally controlled despite current management strategies 3<br />

1. Respiratory insufficiency—pathophysiology, diagnosis, oxygen therapy. In: Guyton AC, Hall JE, eds. Textbook of Medical Physiology.<br />

9th ed. Philadelphia, Pa: WB Saunders Company; 1996:537–545. 2. Corry DB, Kheradmand F. Induction and regulation of the IgE<br />

response. Nature. 1999;402(suppl):B18–B23. 3. Global Initiative for Asthma® (GINA). Global Strategy for Asthma Management and<br />

Prevention. Bethesda, Md: National Institutes of Health. National Heart, Lung, and Blood Institute; revised 2002. NIH publication 02-3659.<br />

©2003 Genentech, Inc. and Novartis Pharmaceuticals Corporation<br />

M00292-R1/CXOL-1002 2/03 Printed in U.S.A.<br />

RESEARCH TARGETING IgE—<br />

Imagine where the science can take us<br />

®<br />

61

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