© Ricardo Buzó

More documents

Recommendations

Info

Stereotact Funct Neurosurg. 2008;86(2):87-91. Epub 2007 Dec 12. Links Microelectrode-guided deep brain stimulation for Tourette syndrome: within-subject comparison of different stimulation sites. Shields DC, Cheng ML, Flaherty AW, Gale JT, Eskandar EN. Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Mass., USA. BACKGROUND: As medical therapy for Tourette syndrome (TS) is ineffective in a small subset of patients, surgical interventions, including deep brain stimulation at various sites, have been developed in recent years. CASE DESCRIPTION: We present the case of a 40-year-old woman with TS whose severe tics had caused unilateral blindness. Despite trials of more than 40 medications, her symptoms improved significantly only after placement of bilateral deep brain stimulators in the anterior inferior internal capsule. However, symptomatic improvement was not complete, and her electrode connections eventually became permanently damaged by the remaining retrocollic jerks. She underwent removal of the internal capsule electrodes and placement of centromedian nucleus thalamic stimulators with significantly improved tic control. CONCLUSION: Whereas the anterior internal capsule site had also produced psychiatric side effects such as altered mood and impulse control, the thalamic site has not done so to date. Thus, distinct surgical targets for TS may be appropriate for patients with specific comorbidities. (c) 2007 S. Karger AG, Basel PMID: 18073521 [PubMed - indexed for MEDLINE]
“Cualquier descubrimiento sobre Tourette ampliará sin duda enormemente nuestra comprensión de la naturaleza humana en general…No conozco ningún otro Síndrome que posea un interés comparable” Alexander R. LURIA
Page 1 and 2: © Ricardo Buzó
Page 5: Hiperactividad orbitofrontal extern
Page 8 and 9: CLINICA
Page 17: Mov Disord. 2003 Dec;18(12):1530-3.
Page 27 and 28: Jankovic J. Tourette's syndrome. Ne
Page 29 and 30: ETIOPATOGENIA
Page 32: MODELO FISIOPATOLOGICO DEL SINDROME
Page 35 and 36: This chart shows subregions of the
Page 37: J Korean Med Sci. 2002 Aug;17(4):53
Page 45 and 46: PARACLINICA
Page 47 and 48: SPECT CEREBRAL SPECT cerebral de lo
Page 49: TRATAMIENTO

© Ricardo Buzó

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?