Extent of Absorption
Extent of Absorption
Extent of Absorption
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4. Effect <strong>of</strong> pH<br />
The pH <strong>of</strong> the blood or tissue affect the<br />
ionization <strong>of</strong> the drug and thus its distribution<br />
5. Age<br />
In old people, Protein binding and body water<br />
will decrease, thus increasing the concentration<br />
<strong>of</strong> the drug per unit time<br />
6. Existence <strong>of</strong> storage sites:<br />
These include: Adipose tissue, plasma proteins,<br />
liver and kidneys, and bone<br />
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