October 17-21 2015 Baltimore Maryland

impact diseases were the least present. Within this group, 44.4%(4) have not
treatment and 55.6%(5) have a possible treatment. The 21-Hydroxylase-
Deficient Congenital Nonclassical Adrenal Hyperplasia (1:9), Familial Mediterranean
Fever (1:100) and Pseudocholinesterase Deficiency (1:50) were
the most prevalent detected diseases.
CONCLUSIONS: It is clear that the screening of genetic diseases
for oocyte donors is part of the necessary studies to reduce the risk of children
born from this kind of treatment. We can infer that the genetic screening of
recessive mutations in people who donate their gametes will further reduce
the risk of certain genetic diseases transmission.
OUTCOME PREDICTORS - CLINICAL: ART 1
O-37 Monday, October 19, 2015 11:15 AM
MATERNAL PREGNANCY AND BIRTH COMPLICATIONS BY
FERTILITY STATUS: THE MASSACHUSETTS OUTCOMES STUDY
OF ASSISTED REPRODUCTIVE TECHNOLOGIES. B. Luke, a
D. Gopal, b J. E. Stern, c E. Declercq, b L. Hoang, b M. Kotelchuck, d
H. Diop. e a Obstetrics, Gynecology, and Reproductive Biology, Michigan
State University, East Lansing, MI; b Community Health Sciences, Boston
University, Boston, MA; c Geisel School of Medicine at Dartmouth, Lebanon,
NH; d MGH Center for Child & Adolscent Health Research and Policy, Mass-
General Hospital for Children, Boston, MA; e Bureau of Family Health and
Nutrition, Massachusetts Department of Public Health, Boston, MA.
OBJECTIVE: To evaluate the effect of maternal fertility status on the risk
of pregnancy and birth complications.
DESIGN: Longitudinal cohort study, linking cycles from the SART
CORS, hospital discharge, and vital records from 2004-2010 in Massachusetts.
MATERIALS AND METHODS: The study included three fertility
groups: women without ART or other infertility treatment (fertile); women
with indicators of subfertility but no ART treatment (subfertile), and women
with ART treatment. The risks of seven adverse outcomes were modeled using
logistic regression, adjusted for parental ages, race/ethnicity, education,
payor status, maternal pre-existing conditions (diabetes and chronic hypertension),
and plurality, and reported as adjusted odds ratios (AORs) and
95% confidence intervals.
Pregnancy Outcomes and Multiple Pregnancy Rate based on Age and Number
of Embryos Transferred
Compliant
(1 ET)