October 17-21 2015 Baltimore Maryland

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potential of monosomy embryos is negligible compared to their trisomy counterparts, yet the cause for this is unknown. Our previous investigation of epigenetic modifiers uncovered a decreased expression of DNA methyltransferase enzymes in monosomy blastocysts, as well as a hypomethylated state limited to the monosomic chromosome. This study was thus extended to determine the DNA methylation profiles of imprinting control regions (ICRs) present on the affected chromosomes. DESIGN: Research study. MATERIALS AND METHODS: Surplus cryopreserved human blastocysts were donated with IRB approval. Trophectoderm biopsies followed by comprehensive chromosomal screening using qPCR (RMA-NJ) determined chromosome constitution. Individual monosomy 11 (n¼10) or 15 (n¼10), trisomy 11 (n¼10) or 15 (n¼10), and euploid oocyte donor blastocysts (controls; n¼20) underwent bisulfite conversion and PCR amplification to determine the DNA methylation profiles of two maternally methylated ICRs, KCNQ1OT1 (11p15.5) and SNRPN (15q11.2). Statistical analysis was calculated using the Student’s t-Test, with significance at p
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Page 6: O-4 Monday, October 19, 2015 12:00
Page 10: RESULTS: Ethnic distribution did no
Page 14: were collected. We used microanalyt
Page 22: to touch test notable for a 44% fer
Page 26: MATERIALS AND METHODS: Patients wit
Page 30: impact diseases were the least pres
Page 34: OBJECTIVE: ASRM and SART regularly
Page 40: with chromosome aneuploidy and embr
Page 44: and tended to positively correlate
Page 48: Augmented PR activity by AKAP13 in
Page 56: DESIGN: Prospective cohort study MA
Page 60: with sufficient certainty and accur
Page 64: likely to feel isolated or guilty t
Page 68: 2009-2010, pre-program, to 2012-201
Page 76: action. While additional studies to
Page 80: are four different PTGERs, our geno
Page 84: DESIGN: Randomized, controlled, pro
Page 88:
Number of veins ligated during vari
Page 92:
ANOVA, Welch’s t-test and multiva
Page 96:
Science, Icahn School of Medicine a
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(5.28) years in the frozen-thawed g
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presenting moderate/severe OHSS had
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for the evaluation of oocyte qualit
Page 112:
O-141 Tuesday, October 20, 2015 11:
Page 116:
Comparison according to blastocelic
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MATERIALS AND METHODS: One-cell emb
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pre- and post-implantation fetal gr
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GENETIC COUNSELING 1 O-163 Tuesday,
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for 8511 patients. Individuals were
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discarded (egg donation) and male f
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O-179 Tuesday, October 20, 2015 12:
Page 144:
(ECM) expression in leiomyomas comp
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draw and 52% completed a post-test
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O-195 Wednesday, October 21, 2015 1
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Supported by: European Union Sevent
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CONCLUSIONS: Myometrial stem cells
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(evaluated by HSCORE) and real-time
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Page 176:
DESIGN: Cross sectional observation
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Effectiveness of this method was te
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Page 188:
5.6 (1-46), number euploid was 3.7
Page 192:
MATERIALS AND METHODS: ICSI videos
Page 196:
were not. The identification of inc
Page 200:
clinic, or if embryo transfer occur
Page 204:
the ultimate outcome being a child
Page 208:
calories, male body mass index, rac
Page 212:
M. S. Christianson, b W. Shen. a a
Page 216:
Fisher’s exact test for small fre
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symptoms were assessed up to 4 time
Page 224:
women aged 25 years who had interco
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DESIGN: A total of 28 patients with
Page 232:
OBJECTIVE: Obstetricians often reco
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6.4% (3.7-10.9), and 9.8% (6.0-15.4
Page 240:
P-42 Tuesday, October 20, 2015 OBES
Page 244:
MATERIALS AND METHODS: We reviewed
Page 248:
dopamine. It has been reported that
Page 252:
ovarian response to gonadotropin st
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and cardiovascular parameters: body
Page 260:
explore the relationship between sR
Page 264:
similar cycle outcomes can be achie
Page 268:
Comparison of groups related to cyc
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at -80 C and available for analysi
Page 276:
P-94 Tuesday, October 20, 2015 DIET
Page 280:
MATERIALS AND METHODS: This study i
Page 284:
mean cumulative pre-test scores. At
Page 288:
P-110 Tuesday, October 20, 2015 OXI
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P-116 Tuesday, October 20, 2015 EST
Page 296:
showed that there was no DNA methyl
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corresponding to embryo transfer co
Page 304:
P-133 Tuesday, October 20, 2015 THE
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concerns (75%) in comparison to oth
Page 312:
indicating this region is a T-DMR.
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MATERIALS AND METHODS: Normal endom
Page 320:
Obstetrics and Gynecology, West Chi
Page 324:
Medical School, Boston, MA; d Brigh
Page 328:
MATERIALS AND METHODS: 62 women wit
Page 332:
comparing oxidative damage in endom
Page 336:
P-180 Tuesday, October 20, 2015 END
Page 340:
P-186 Tuesday, October 20, 2015 USE
Page 344:
OBJECTIVE: It has been reported tha
Page 348:
P-198 Tuesday, October 20, 2015 EVA
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procedures; however when combined,
Page 356:
MATERIALS AND METHODS: We analyzed
Page 360:
(LOS), re-intervention, and readmis
Page 364:
OR 1.91, 95% CI 1.68-2.16). Gonadot
Page 368:
CONCLUSIONS: There was no significa
Page 372:
assessment of clinical efficacy reg
Page 376:
Table 1. embryos Y Chromosome Day 3
Page 380:
RESULTS: The majority of PGS cases
Page 384:
P-251 Tuesday, October 20, 2015 CUM
Page 388:
(53.8% vs. 22.5%; p¼ .027). In 19
Page 392:
Technology. Role of assisted hatchi
Page 396:
P-269 Tuesday, October 20, 2015 OOC
Page 400:
P-275 Tuesday, October 20, 2015 NON
Page 404:
de Ciencias Medicas da Santa Casa d
Page 408:
and the odds of having a blastocyst
Page 412:
CONCLUSIONS: The SART CORS field fo
Page 416:
MATERIALS AND METHODS: From 2004-20
Page 420:
the factors that influenced the mos
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was made 30 minutes after IVI (IVI
Page 428:
MATERIALS AND METHODS: Included in
Page 432:
D3eSET and 153 had elective single
Page 436:
in blastocyst development, aneuploi
Page 440:
All women were under 38 years of ag
Page 444:
questionnaires, including report of
Page 448:
OBJECTIVE: To determine whether ant
Page 452:
cycles and stored at -20 C. Media
Page 456:
(S; 20% O2, Thermo Forma, USA). In
Page 460:
maintain potency and block differen
Page 464:
P-370 Tuesday, October 20, 2015 DOE
Page 468:
P-376 Wednesday, October 21, 2015 B
Page 472:
were included. Only the first cycle
Page 476:
DESIGN: Retrospective cohort study
Page 480:
2010 morphologic criteria. Beyond t
Page 484:
CONCLUSIONS: TPMSC is an independen
Page 488:
Table 1. Group 1 Group 2 P Age 33.7
Page 492:
OH; b Case Western Reserve Universi
Page 496:
changes involved with impaired sper
Page 500:
Medicine, Feinberg SOM- Northwester
Page 504:
again AFC had better accuracy (AUC
Page 508:
controlled primordial follicle acti
Page 512:
CONCLUSIONS: Compared to convention
Page 516:
OBJECTIVE: This study was for aim,
Page 520:
Histologic analysis of the tissue s
Page 524:
FERTILITY PRESERVATION P-455 Wednes
Page 528:
DESIGN: In vivo mouse study. MATERI
Page 532:
P-468 Wednesday, October 21, 2015 F
Page 536:
P¼ 0.31) compared to the control g
Page 540:
Baseline characteristics and outcom
Page 544:
micronized progesterone 400 mg b.d.
Page 548:
P-490 Wednesday, October 21, 2015 I
Page 552:
P-496 Wednesday, October 21, 2015 D
Page 556:
CONCLUSIONS: Aneuploidy screening w
Page 560:
RESULTS: The diagnostic rates were
Page 564:
P-514 Wednesday, October 21, 2015 L
Page 568:
OBJECTIVE: To define euploid implan
Page 572:
20 (n¼1). There was no difference
Page 576:
11. Clark R, Leonessa F, Welch JN,
Page 580:
and 11.5%. The ROC curve analysis o
Page 584:
was a trend towards a higher BMI wi
Page 588:
formulations. 42 (48.3%) used cutan
Page 592:
SPERM BIOLOGY P-554 Wednesday, Octo
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organ development, development and
Page 600:
14.06, respectively. There was a si
Page 604:
MATERIALS AND METHODS: Sperm sample
Page 608:
RESULTS: Following AOA, fertilizati
Page 612:
MATERIALS AND METHODS: One hundred
Page 616:
BFRs for fresh Aut (959/1539; 59%)
Page 620:
test for numerical variables and ch
Page 624:
and significance differences betwee
Page 628:
patients. In contrast, the arrest r
Page 632:
Mono media is a single formulation.
Page 636:
and Day5 using normal 35mm dish. Th
Page 640:
continuous variables. Logistic regr
Page 644:
Outcomes in patients with Low and V
Page 648:
TRANSCRIPTIONAL COMPARISON OF NATUR
Page 652:
with 1,2 versus 3,0, and the luteal
Page 656:
analysis in integrating available l
Page 660:
OBJECTIVE: Women of reproductive ag
Page 664:
EMBRYO TRANSFER Treatment outcomes.
Page 668:
hatching with a differentiated inne
Page 672:
HOM gestations since the publicatio
Page 676:
alance between the potential cryo-d
Page 680:
are generated, the implantation rat
Page 684:
(embryos were biopsied day 5, vitri
Page 688:
predictive power in oocyte donor ag
Page 692:
Summary of the main findings. Vagin
Page 696:
P-702 Wednesday, October 21, 2015 W
Page 700:
were included in this study. Exclus
Page 704:
pregnancy (n ¼56) and clinical pre
Page 708:
from off-site work, as shown in the
Page 712:
RESULTS: Correlational analyses sho
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(SC), Hypomania (MA), and Social In
Page 720:
analyses were used to identify fact
Page 724:
AUTHOR INDEX Aballa, T., O-19 Aball
Page 728:
Butler, V. L., P-197 Butts, S., O-2
Page 732:
Elliot, M. C., P-332 Elliott, T., O
Page 736:
Homel, P., P-264 Homer, M. V., O-7,
Page 740:
Leung, P. C. K., P-3, P-701 Leung,
Page 744:
Obata, R., P-57, P-575 O’Brien, J
Page 748:
Schoolcraft, W. B., O-32, O-46, O-4
Page 752:
Villette, C., P-418 Viloria, T., O-
Page 756:
TOPIC INDEX ART- In Vitro Fertiliza
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AUTHOR AND SPOUSE/PARTNER DISCLOSUR
Page 764:
Craig, L.T. B. Ferring Pharmaceutic
Page 768:
Katilius, J. Prima-Temp,Inc, Paid c
Page 772:
Sammel, M. D. Swiss Precision Diagn
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October 17-21 2015 Baltimore Maryland

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