Soft Matter and Functional Materials - Helmholtz-Zentrum Berlin

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$Math.-Nat. - Papier - Helmholtz-Zentrum Berlin$

Polymer Physics ___________________________________________________________________ Laboratory for Microfluidics: Sebastian Seiffert Microfluidic devices are networks of micron scale channels integrated to perform functions. These functions can be divided into two broad classes. In one class, microfluidic devices perform chemical and biological assays by introducing cells, beads, and other reagents into the device and then merge, mix, and split them. In the second class, microfluidic devices fabricate fluid droplets of precisely controlled geometry, which then serve to synthesize microparticles. For this purpose, solutions or melts of monomers or crosslinkable polymers are introduced into the device, along with an immiscible carrier phase; the devices disperse these solutions into equally sized micro-droplets, which can then be solidified by polymerization, crosslinking, or crystallization, as illustrated in the figure. The principle of the microfluidic drop formation can be explained using a water faucet as an example: if a faucet operates a low flow rate, water drips out one drop at a time. The drop size is determined by a balance between the surface forces of the hanging drop and its weight, and therefore depends on the surface tension of the fluid and the size of the faucet. Since both these parameters are constant, all drops exhibit a narrow size distribution. The same principle is employed in microfluidic channels, such that the droplet size obtained in these channels is highly controllable. Microfluidic devices also offer versatile means to form complex structures such as non-spherical droplets, anisotropic droplets, or multiple-emulsion “droplets-in-droplets”. These structures can be retained by subsequent droplet solidification, typically achieved through rapid on-chip polymerization, thereby yielding monodisperse particles with complex architecture. Another application of microfluidic channels encompasses their implementation in scattering experiments. The strategy for this is to place an array of microchannels into an x-ray or neutron beam and to probe the species of interest while flowing through the channels. The channels to be used for this purpose can either have constant dimensions, or they may exhibit varying width and height, allowing the samples to be probed in uni- or biaxially deformed states. As an alternative, a semi-static method aims to use a microfluidic platform which resembles a “parking lot for droplets”, allowing single deformable samples such as droplets or microgel particles to be fixed in addressable positions. Subsequent longtermobservation can serve to monitor ageing or relaxation processes. Microfluidic Emulsification Pre-Microparticle Emulsion Monodisperse Microgels Microfluidic fabrication of polymer microgel particles. A flow focusing microfluidic device serves to form monodisperse pre-micrpoparticle droplets, which then serve to template monodisperse microgels.
Soft Matter and Functional Materials Research
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X-Ray Microscopy __________________
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Soft Matter Theory ________________
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Soft Matter and Functional Material
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Selected publications 1. J. M. Brad
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Prof. Dr. Joachim Dzubiella (1975)
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Goerigk, G.: Anomalous Small-Angle
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Dr. Thomas Hauß (1958) F-I2 Soft M
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Dr. Martin Hoffmann (1981) F-I2 Sof
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Selected Publications 1. Y. Lu, Y.
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Priv. Doz. Dr. Gerd Schneider (1963
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Dr. Sebastian Seiffert (Dipl.-Chem.
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Dr. Roland Steitz (1960) F-I2 Soft
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Dr. Manfred S. Weiss (1963) Macromo
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Soft Matter and Functional Material
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Soft Matter and Functional Materials - Helmholtz-Zentrum Berlin

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