21.04.2016 Views

GETTING THE WORD OUT

New_Scientist_2_April_2016@englishmagazines

New_Scientist_2_April_2016@englishmagazines

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

FROZEN STIFF<br />

Did interstellar cloud<br />

kill off the dinosaurs?<br />

IMPRECISION ENGINEERING<br />

To make computers better,<br />

try making them worse<br />

YOU SWINE!<br />

Problem porkers wreak<br />

havoc worldwide<br />

WEEKLY April 2 -8, 2016<br />

MINIMAL LIFE We’ve made the tiniest genome that works<br />

To explain our cosmic backyard,<br />

we need to break gravity<br />

No3067 US$5.95 CAN$5.95<br />

1 3<br />

0 70989 30690 5<br />

Science and technology news<br />

www.newscientist.com<br />

US jobs in science<br />

<strong>GETTING</strong> <strong>THE</strong> <strong>WORD</strong> <strong>OUT</strong> Stuttering starts deep in the brain


CONTENTS<br />

Volume 230 No 3067<br />

This issue online<br />

newscientist.com/issue/3067<br />

News<br />

6<br />

Unlocking the<br />

essence of life<br />

We’ve made the tiniest<br />

genome that works<br />

On the cover<br />

30<br />

Our impossible<br />

galaxy<br />

To explain our cosmic<br />

backyard, we need to<br />

break gravity<br />

Cover image<br />

Lynette Cook/Science Photo Library<br />

Features<br />

34<br />

Getting the<br />

word out<br />

Stuttering starts<br />

deep in the brain<br />

SERGE PICARD/AGENCE VU/CAMERAPRESS TOM DEERINCK & MARK ELLISMAN/NCMIR/UCSD<br />

8 Frozen stiff<br />

Did an interstellar cloud<br />

kill off the dinosaurs?<br />

36 Imprecision engineering<br />

To make computers<br />

better, make them worse<br />

40 You swine!<br />

Porkers wreak havoc<br />

6 Minimal life<br />

Tiniest working genome<br />

34 Getting the word out<br />

Stuttering and the brain<br />

Coming next week…<br />

On the road<br />

Is migration really a crisis?<br />

Black holes unmasked<br />

Frozen universe reveals their secrets<br />

Leaders<br />

3 Exploring the essentials of life isn’t about<br />

playing god. To err should be inhuman<br />

News<br />

4 UPFRONT<br />

Could bomb sensors stop another Brussels?<br />

Fast Antarctic ice melt could see catastrophic<br />

sea rise. Gecko Grippers head to space<br />

6 THIS WEEK<br />

Did a cosmic cloud kill the dinosaurs? Mars<br />

had a short-lived ocean. Prairie dog serial<br />

killers. The twins who felt fear for the first<br />

time. Lock up CO 2 in building materials. How<br />

brain-zapping works. Bright spots on Ceres.<br />

Stacking oranges in 24 dimensions<br />

15 IN BRIEF<br />

Migrating birds stay in UK for longer. Cats<br />

give us rage. Ghost galaxies. Exercise for a<br />

young brain. Unlocking ancient scroll library<br />

Technology<br />

18 Get immersed as first virtual reality games<br />

go on sale. Inside the factory of the future<br />

Aperture<br />

22 What the Zika virus looks like – probably<br />

Opinion<br />

24 Hinkley’s point Paul Ekins urges rethinking<br />

the world’s biggest nuclear power project<br />

24 US in Cuba Michael Clegg on a hopeful start<br />

25 INSIGHT Londoners’ toxic air nightmare<br />

28 Roborescue It’s time robots took their place<br />

in search and rescue, says Robin Murphy<br />

Features<br />

30 Our impossible galaxy (see above left)<br />

34 Getting the word out (see left)<br />

36 Imprecision engineering To make<br />

computers better, try making them worse<br />

40 You swine! Problem porkers wreak havoc<br />

worldwide<br />

CultureLab<br />

42 Animal crackers Pretending to be other<br />

creatures is an altogether human game<br />

43 A drug to make us good Hunting for<br />

morality in a neuroscientific mess<br />

Regulars<br />

52 LETTERS Theory proposes<br />

56 FEEDBACK When is a drug not a drug?<br />

57 <strong>THE</strong> LAST <strong>WORD</strong> Atomic bonds<br />

2 April 2016 | NewScientist | 1


LEADERS<br />

LOCATIONS<br />

USA<br />

50 Hampshire St, Floor 5,<br />

Cambridge, MA 02139<br />

Please direct telephone enquiries to<br />

our UK office +44 (0) 20 7611 1200<br />

UK<br />

110 High Holborn,<br />

London, WC1V 6EU<br />

Tel +44 (0) 20 7611 1200<br />

Fax +44 (0) 20 7611 1250<br />

Australia<br />

Tower 2, 475 Victoria Avenue,<br />

Chatswood, NSW 2067<br />

Tel +61 2 9422 8559<br />

Fax +61 2 9422 8552<br />

ELI MEIR KAPLAN/FOR <strong>THE</strong> WASHINGTON POST VIA GETTY<br />

SUBSCRIPTION SERVICE<br />

For our latest subscription offers, visit<br />

newscientist.com/subscribe<br />

Customer and subscription services are<br />

also available by:<br />

Telephone 1-888-822-3242<br />

Email subscribe@newscientist.com<br />

Web newscientist.com/subscribe<br />

Mail New Scientist, PO Box 3806,<br />

Chesterfield, MO 63006-9953 USA<br />

One year subscription (51 issues) $154<br />

CONTACTS<br />

Contact us<br />

newscientist.com/contact<br />

Who’s who<br />

newscientist.com/people<br />

General & media enquiries<br />

enquiries@newscientist.com<br />

Editorial<br />

Tel 781 734 8770<br />

news@newscientist.com<br />

features@newscientist.com<br />

opinion@newscientist.com<br />

Picture desk<br />

Tel +44 (0) 20 7611 1268<br />

Display advertising<br />

Tel 781 734 8770<br />

displaysales@newscientist.com<br />

Recruitment advertising<br />

Tel 781 734 8770<br />

nssales@newscientist.com<br />

Newsstand<br />

Tel 212 237 7987<br />

Distributed by Time/Warner Retail<br />

Sales and Marketing, 260 Cherry Hill<br />

Road, Parsippany, NJ 07054<br />

Syndication<br />

Tribune Content Agency<br />

Tel 800 637 4082<br />

© 2016 Reed Business<br />

Information Ltd, England.<br />

New Scientist ISSN 0262 4079 is<br />

published weekly except for the last<br />

week in December by Reed Business<br />

Information Ltd, England.<br />

New Scientist (Online) ISSN 2059 5387<br />

New Scientist at Reed Business<br />

Information, c/o Schnell Publishing Co.<br />

Inc., 225 Wyman Street, Waltham,<br />

MA 02451.<br />

Periodicals postage paid at<br />

Boston, MA and other mailing offices.<br />

Postmaster: Send address changes<br />

to New Scientist, PO Box 3806,<br />

Chesterfield, MO 63006-9953, USA.<br />

Registered at the Post Office as a<br />

newspaper and printed in USA by Fry<br />

Communications Inc, Mechanicsburg,<br />

PA 17055<br />

Bare necessities<br />

Exploring the essentials of life isn’t about playing God<br />

HAVE we found the essentials of<br />

life? A team in the US has reduced<br />

the number of genes in a modest<br />

bug called Mycoplasma mycoides<br />

by almost half, creating the tiniest<br />

genome that can support vital<br />

survival functions (see page 6).<br />

The new strain is called JVCIsyn3.0,<br />

the letters coming from<br />

the name of the J. Craig Venter<br />

Institute in La Jolla, California.<br />

The institute is named after the<br />

charismatic biotechnologist<br />

who is almost as well known for<br />

his swagger as for his scientific<br />

achievements. The first human<br />

genome to be fully sequenced<br />

was Venter’s own, and he has in<br />

the past drawn opprobrium for<br />

attempting to patent genes. His<br />

apparent grandiosity irks more<br />

buttoned-down colleagues.<br />

And his ambition prompts those<br />

averse to genetic engineering to<br />

invoke inchoate risks, frequently<br />

buttressed by the claim that it<br />

amounts to “playing God”. This<br />

time, Venter’s rhetoric has been<br />

reined in a little. The genome of<br />

JVCI-syn3.0, while put together<br />

on a computer and assembled by<br />

DNA sequencers, includes no new<br />

or artificial genes. If anything, its<br />

creation shows the limits of our<br />

power and depth of our ignorance:<br />

we have no idea what a third of the<br />

genes the team found actually do.<br />

But now we can start figuring<br />

out what the essentials of life<br />

really are. That will, Venter insists,<br />

invigorate synthetic biology,<br />

with benefits for all of us: he, and<br />

Toerrshouldbeinhuman<br />

NEURAL networks, like the ones<br />

grabbing headlines for winning<br />

boardgames or driving cars,<br />

depend on huge amounts of<br />

computing hardware. That in<br />

turn means a colossal amount<br />

of power: the next wave may<br />

consume millions of watts each.<br />

That’s one reason why some<br />

suggest we rethink what we want<br />

computers to be. Reducing the<br />

precision with which they analyse<br />

problems, and putting up with<br />

the odd“error”, can cut zeroes off<br />

their energy consumption (see<br />

page 36). And it has precedent in<br />

the human brain – an unrivalled<br />

piece of hardware using electrical<br />

fluctuations and requiring a<br />

million times less power than<br />

a computer.<br />

Introducing error will also make<br />

computers better at handling<br />

the real world. Neural networks,<br />

others, want to design organisms<br />

that can make biofuels, protein<br />

or vaccines more efficiently.<br />

Since Venter made his first<br />

synthetic cell in 2010, however,<br />

the ease of gene editing has<br />

exploded. This allows scientists to<br />

tweak genomes far more cheaply<br />

than building them from scratch.<br />

The CRISPR technique, which has<br />

itself generated much ethical<br />

controversy, might end up the<br />

more practical and widespread<br />

method. Either way, far from<br />

wilfully taking risks – playing<br />

God, if you really must – synthetic<br />

biologists are developing the<br />

expertise to address very human<br />

needs. Venter’s bullish approach<br />

has brought that a step closer.<br />

Let him swagger. ■<br />

loosely modelled on the brain,<br />

capture some of its problemsolving<br />

capacity. AlphaGo<br />

surprised opponents and<br />

designers alike with Go moves<br />

described by some as “intuitive”.<br />

Computers that play Go,<br />

understand human language and<br />

behaviour, spot patterns across<br />

databases of genetic information<br />

or forecast economic and climate<br />

trends do not deal in absolutes.<br />

It is their rough guesses that will<br />

bring us closest to comprehensive<br />

artificial intelligence. ■<br />

2 April 2016 | NewScientist | 3


UPFRONT<br />

ADAM BERRY/GETTY<br />

Satellite lost<br />

JUNKED? Hitomi, a Japanese<br />

astronomy satellite, seems to be<br />

tumbling through space, and may<br />

have broken up. It was due to<br />

come online on 26 March, but<br />

failed to communicate with Earth.<br />

A tweet by the US Joint Space<br />

Operations Center reported five<br />

pieces of debris around the<br />

satellite shortly afterwards.<br />

All may not be lost. The Japan<br />

Aerospace Exploration Agency<br />

heard a brief burst of signal from<br />

the craft, and video taken from<br />

the ground suggests it is falling<br />

through space.<br />

“That indicates the sat was<br />

at that point alive, just unable<br />

to point its antenna at Earth,”<br />

says Jonathan McDowell at the<br />

“If we never hear from<br />

the satellite again,<br />

I would be devastated<br />

but not surprised”<br />

Can we sniff out bombs?<br />

LAST week, terrorists walked into scanned by an array of sensors as<br />

Brussels’ Zaventem airport and<br />

they walk through the tunnel to<br />

detonated bomb-laden luggage get into airports or train stations.<br />

in the check-in area. They also<br />

The Lincoln Laboratory at<br />

bombed a subway station.<br />

the Massachusetts Institute of<br />

As New Scientist went to press,<br />

Technology has a different approach.<br />

35 people had been killed and<br />

A team there has turned to lasers<br />

hundreds wounded.<br />

to “sniff” explosives from a distance.<br />

Can we stop attacks like this?<br />

The lab says it can scan spaces like<br />

Airport security focuses on keeping check-in areas from 100 metres<br />

explosives off planes. Stopping<br />

away by sweeping them with<br />

bombs detonating in crowded<br />

lasers tuned to frequencies that<br />

check-in areas and transit terminals vaporise molecules found in<br />

is a bigger challenge. Security<br />

bombs. This material makes a tiny<br />

checkpoints work, but they cause sound as it vaporises, which is<br />

delays and create queues that can amplified and detected.<br />

also be a target. But there are new<br />

Lasers are also used in a device<br />

ways to scan people as they walk. called G-Scan, developed by Laser<br />

Cameron Ritchie, head of<br />

Detect Systems of Ramat Gan in Israel.<br />

technology at the US-based security This fires a green laser at a target then<br />

firm Morpho, is working on a “tunnel uses Raman spectroscopy to<br />

of truth”. Passengers would be<br />

“fingerprint” the molecules that<br />

scatter light back. It can identify<br />

anything visible, including bottle<br />

contents or surface smears.<br />

Detecting explosive material from<br />

a distance would enable security<br />

services to track down bomb-making<br />

supplies – not just finished weapons.<br />

By scanning for telltale chemicals on<br />

people’s bodies and clothes as they<br />

move around cities, security services<br />

may be able to catch suspects before<br />

they have built their device.<br />

One concern is that such sensitive<br />

detectors may trigger many false<br />

alarms. There is also the question<br />

of whether airport and train security<br />

staff can respond to a positive signal<br />

quickly and effectively enough to<br />

neutralise a threat, says Brian<br />

Jenkins, a security researcher at the<br />

Rand Corporation. “You can’t just yell,<br />

‘hey you with the bomb’.”<br />

Harvard-Smithsonian Center for<br />

Astrophysics. He says it might be<br />

possible to talk to Hitomi and<br />

stop it tumbling. “But if you told<br />

me we were never going to hear<br />

from the sat again, I would be<br />

devastated but not surprised,”<br />

he says.<br />

Hitomi’s mission is to<br />

observe the universe in X-rays,<br />

investigating matters such as<br />

the birth of black holes and the<br />

origins of cosmic rays.<br />

Space geckos<br />

IN A few years, the exterior of the<br />

International Space Station could<br />

be crawling with geckos. It’s not<br />

an alien invasion, or the plot of a<br />

low-budget sci-fi movie. The<br />

robotic geckos could follow from<br />

an experiment NASA launched to<br />

the International Space Station<br />

last week aboard an uncrewed<br />

Cygnus spacecraft.<br />

The Gecko Gripper devices use<br />

tiny artificial hairs that replicate<br />

the ones geckos use to climb walls.<br />

They are designed to help<br />

4 | NewScientist | 2 April 2016


For new stories every day, visit newscientist.com/news<br />

60 SECONDS<br />

astronauts keep track of objects in<br />

zero gravity, and enable robots to<br />

crawl around a spacecraft to<br />

inspect and repair it.<br />

The bots have already been<br />

tested on parabolic aircraft flights,<br />

where they grabbed and<br />

manipulated 10-kilogram and<br />

100-kg objects during 20-second<br />

periods of microgravity. On the<br />

ISS trip, astronauts will test the<br />

system by attaching five devices<br />

in a range of sizes to 30 surfaces<br />

inside the space station at<br />

different angles, to check how well<br />

they grip. The devices will be left<br />

in place for periods of time<br />

between two weeks and a year.<br />

HIV prevention<br />

COLIN MONTEATH/HEDGEHOG HOUSE/MINDEN<br />

Zika’s arrival traced<br />

ONE person carried the Zika virus<br />

to the Americas a full two years<br />

before its detection there last year.<br />

Brazil was the first country in<br />

the Americas to report Zika, in<br />

May 2015, and the virus has since<br />

infected hundreds of thousands<br />

of people in 33 countries. The<br />

virus is native to Africa but in the<br />

last 10 years it jumped to some of<br />

the islands of Micronesia and<br />

Polynesia in the Pacific.<br />

A genetic analysis suggests the<br />

virus in the Americas came from<br />

an individual infected in<br />

Polynesia, and that it arrived<br />

IT SAVES money and prolongs A MASSIVE rise in sea level is coming,<br />

lives, but who should pay – the UK and it will trigger climate chaos<br />

health service or local councils? around the world. That was the<br />

Trials around the world have message from a controversial recent<br />

shown that Truvada, an antiviral paper by climate scientist James<br />

drug, helps prevent uninfected, Hansen. It was slated by many for<br />

at-risk people from getting HIV. assuming – rather than showing –<br />

After 18 months of negotiations, that sea level could rise by between<br />

it looked certain that NHS England 1 and 5 metres by 2100.<br />

would foot the bill if Truvada was But now, just a week after being<br />

rolled out across England. Instead, formally published, it is being backed<br />

on 21 March NHS England<br />

up by another study. “He was<br />

announced it would mount a<br />

speculating on massive fresh water<br />

two-year, £2 million pilot study of discharge to the ocean that I don’t<br />

500 men at high risk of infection think anybody thought was possible<br />

to assess the efficacy and cost.<br />

before,” says Rob DeConto of the<br />

NHS England also backed away University of Massachusettsfrom<br />

funding the drug, saying Amherst. “Now we’re about to<br />

that the bill should be met by local publish a paper that says these rates<br />

authorities, which provide other of fresh water input are possible.”<br />

HIV services.<br />

“After 18 months, it’s galling to<br />

be told that,” says Sarah Radcliffe<br />

at the National AIDS Trust charity.<br />

She says there is abundant<br />

evidence that Truvada is effective<br />

and cuts healthcare costs.<br />

Teresa O’Neill of London<br />

Councils says the capital has the<br />

country’s highest rates of HIV so<br />

councils there would face a high<br />

bill. She points out that it costs<br />

£380,000 to treat an HIV-positive<br />

person for life, versus £4700 to<br />

supply Truvada for a year, so you’d<br />

have to take the drug for 80 years<br />

before it became more expensive. –Still there… for now–<br />

between May and December 2013.<br />

“One person with the infection<br />

was bitten by a mosquito and that<br />

chain of infection persisted,” says<br />

Oliver Pybus of the University of<br />

Oxford (Science, doi.org/bdrx).<br />

It isn’t surprising it took two<br />

“Zika in the Americas came<br />

from an individual infected<br />

in Polynesia, and it arrived<br />

in the second half of 2013”<br />

years for Zika’s presence to come<br />

to light. Its symptoms closely<br />

resemble those of dengue and<br />

chikungunya viruses, which were<br />

already circulating.<br />

Catastrophic Antarctic melting<br />

DeConto’s model includes factors<br />

that previous studies omitted. First,<br />

floating ice shelves around Antarctica<br />

will soon be exposed to above-zero<br />

summer air temperatures, speeding<br />

their melt, he says. Second, once the<br />

shelves are gone, the huge ice cliffs<br />

that remain will begin to collapse<br />

(Nature, DOI: 10.1038/nature17145).<br />

DeConto’s findings suggest that<br />

even if countries meet the pledges<br />

made as part of the Paris agreement,<br />

global sea level could still rise 1 metre<br />

by 2100. If emissions keep climbing it<br />

could go up more than 2 metres.<br />

“Today we’re measuring global sea<br />

level rise in millimetres per year,”<br />

DeConto says. “We’re talking about<br />

the potential for centimetres per year<br />

just from Antarctica.”<br />

Bleach bum<br />

It’s a white-out for the Great Barrier<br />

Reef. An aerial survey last week<br />

showed that at least 95 per cent of<br />

the reef’s northern 1000 kilometres<br />

has been severely bleached. It’s the<br />

worst case in history, says the<br />

National Coral Bleaching Taskforce,<br />

which carried out the survey.<br />

Bleaching is caused by high sea<br />

temperatures and can kill coral.<br />

Apple vs FBI<br />

The stand-off is over, for now. The<br />

FBI has successfully broken into the<br />

iPhone belonging to San Bernardino<br />

gunman Syed Rizwan Farook,<br />

bringing to a halt its legal battle with<br />

Apple. In court documents filed on<br />

Monday, the FBI said it no longer<br />

required Apple’s assistance to access<br />

files on the phone, although it hasn’t<br />

made public how it did it.<br />

Stroke protection<br />

Giving mice antibiotics can protect<br />

them from brain damage caused by<br />

stroke. Antibiotics change the makeup<br />

of the mice’s gut bacteria, which<br />

in turn alters the immune cells<br />

that travel to the brain and would<br />

normally cause inflammation. The<br />

treatment appears to reduce cell<br />

destruction by around 60 per cent<br />

(Nature Medicine, doi.org/bdrw).<br />

Green boom<br />

More than twice as much was<br />

spent on new capacity to generate<br />

electricity from renewables like<br />

solar and wind than on power<br />

stations that burn fossil fuels last<br />

year. China was responsible for twothirds<br />

of the renewables investment<br />

in the developing world, and 36 per<br />

cent of the global total.<br />

Permafrost pups<br />

Two puppies that lived 12,460 years<br />

ago have been discovered perfectly<br />

preserved in permafrost in the<br />

northern Russian region of Yakutia.<br />

Last week, one of them underwent<br />

an autopsy so that its organs can be<br />

compared with those of modern<br />

dogs and wolves.<br />

2 April 2016 | NewScientist | 5


THIS WEEK<br />

Smallest ever genome comes to life<br />

Humans built it, but we don’t know what a third of its genes actually do<br />

Andy Coghlan<br />

WE HAVE even further to<br />

go to understand life than we<br />

thought. In creating the latest<br />

landmark synthetic organism –<br />

the world’s first minimal<br />

genome – Craig Venter and his<br />

team have discovered that we<br />

don’t know the functions of<br />

almost a third of the genes<br />

that are vital for life.<br />

“Finding so many genes without<br />

a known function is unsettling,<br />

but it’s exciting because it’s left<br />

us with much still to learn,” says<br />

Alistair Elfick, a bioengineer at the<br />

University of Edinburgh, UK. “It’s<br />

like the ‘dark matter’ of biology.”<br />

Venter, founder of the J. Craig<br />

Venter Institute in La Jolla,<br />

California, has long hoped to<br />

unravel life’s essential toolkit.<br />

Now his team has created the<br />

first minimal genome – the tiniest<br />

possible stash of DNA capable of<br />

supporting life. With 473 genes,<br />

the new cell, JCVI-syn3.0, has at<br />

least 50 fewer genes than nature’s<br />

record-holder for the shortest<br />

genome in a self-sustaining living<br />

organism, Mycoplasma genitalium<br />

(Science, doi.org/bdrz).<br />

The feat builds on JCVI-syn1.0,<br />

LIFE FROM SCRATCH? NOT YET<br />

The design of the first synthetic<br />

minimal genome hints at new ways<br />

to build life. So can we do this from<br />

scratch? Not quite.<br />

For a start, the genome is<br />

based on a slimline version of<br />

one from a naturally occurring<br />

bacterium. The genes were not<br />

dreamed up by people, but<br />

had already evolved in nature.<br />

Also, to make the minimal genome,<br />

researchers didn’t create any new<br />

genes or biological functions,<br />

but simply dumped those not<br />

TOM DEERINCK & MARK ELLISMAN/NCMIR/UNIVERSITY OF CALIFORNIA AT SAN DIEGO<br />

the first living bacterium reliant<br />

on a synthetic copy of an existing<br />

genome, unveiled by Venter in<br />

2010. That genome was designed<br />

in a computer, before assembly<br />

and insertion into cells.<br />

Since then, Venter and his<br />

colleagues, co-led by Clyde<br />

Hutchison, have been whittling<br />

essential for keeping the cell alive.<br />

Then there was the cell itself.<br />

Once the genome was designed<br />

from code on a computer, it had to<br />

be put inside a living cell stripped of<br />

its own, native genome. That cell also<br />

came from a living natural bacterium<br />

that had all the intricate cellular<br />

machinery already in place. And the<br />

process revealed we have no clue<br />

what a third of those vital genes do.<br />

So the ability to create life from<br />

scratch without nature’s help is still<br />

way beyond our capabilities.<br />

–Minimalist life–<br />

down the 901 genes of JCVIsyn1.0<br />

to the minimum for<br />

supporting life. With the help<br />

of transposons –“jumping<br />

genes” that insert themselves<br />

into sections of DNA and disrupt<br />

individual genes – the team<br />

tested which genes a bacterium<br />

can do without. They then<br />

designed a stripped-down<br />

genome, and inserted it into<br />

an existing cell that had had<br />

its own genome removed.<br />

But their first attempts at a<br />

minimalist cell didn’t succeed.<br />

“Every one of our designs failed<br />

because we based these on our<br />

existing knowledge base,”<br />

says Venter.<br />

Their breakthrough came when<br />

they realised that some genes<br />

they thought were expendable<br />

were actually crucial. “To get a<br />

viable cell, the researchers needed<br />

to make discoveries about many<br />

essential and semi-essential genes<br />

that we did not know about,” says<br />

Steven Benner of the Foundation<br />

for Applied Molecular Evolution<br />

in Alachua, Florida.<br />

Surprisingly, some 31 per cent<br />

of the vital genes have no known<br />

function, suggesting we may<br />

still have much to learn about<br />

the cellular processes crucial<br />

to maintaining life. “It means<br />

we know about two-thirds of<br />

essential biology,” says Venter.<br />

Hutchison says it is an “exciting<br />

possibility” that some of these<br />

genes perform key functions<br />

we don’t know of yet.<br />

It’s unclear how genes of<br />

such universal importance<br />

have ducked under the radar for<br />

so long. One possibility is that<br />

the mystery genes do actually<br />

code for known functions, but<br />

their sequences are so different<br />

from their equivalents in other<br />

organisms that we have not been<br />

able to spot and identify them.<br />

Once these mysterious extra<br />

genes were included, the minimal<br />

cells were found to live, grow and<br />

divide, forming clumps of cells in<br />

a dish of nutrients.<br />

Bacterial Eden<br />

Of the genes with known<br />

functions, most make proteins<br />

vital for survival, or check the<br />

fidelity of genome duplication<br />

when the cell divides. Other<br />

essential genes include ones<br />

that code for cell-membrane<br />

proteins and those that enable<br />

the organism to turn nutrients<br />

into energy.<br />

But Venter’s organism was<br />

produced in a bacterial Eden<br />

with every comfort provided,<br />

including a plentiful energy<br />

supply of easy-to-process glucose.<br />

In a harsher environment, such<br />

as soil or water, it would need<br />

extra genes to compete with rivals<br />

for resources, and to survive and<br />

6 | NewScientist | 2 April 2016


In this section<br />

■ Did a cosmic cloud kill the dinosaurs?, page 8<br />

■ The twins who felt fear for the first time, page 9<br />

■ Get immersed as first virtual reality games go on sale, page 18<br />

grow using scarcer sources of<br />

nutrients. “It is likely that their<br />

degree of ‘essential-ness’ will be<br />

environment-specific,”says Elfick.<br />

Next, the team plans to<br />

work out the functions of the<br />

mystery genes. What they find<br />

out could yield insights into<br />

how genes can be repurposed for<br />

synthetic biology, or enable us<br />

to design entirely new genomes<br />

for the first time (see “Life from<br />

scratch?”, below left).<br />

“What we’ve done is important<br />

because it is a step towards<br />

“Finding so many genes<br />

without a known function<br />

is exciting. It’s like the ‘dark<br />

matter’ of biology”<br />

completely understanding how a<br />

living cell works,” says Hutchison.<br />

“If we can really understand this,<br />

then we will be able to design cells<br />

efficiently for the production<br />

of pharmaceutical and other<br />

useful products.”<br />

Bioengineers have applauded<br />

the feat, but some are sceptical<br />

about the commercial potential.<br />

Some believe it is cheaper and<br />

more effective to tweak existing<br />

natural genomes, using<br />

techniques such as gene editing,<br />

than it is to build new genomes<br />

from the bottom up. “It’s a<br />

milestone,” says George Church<br />

of Harvard Medical School,<br />

who is a pioneer of CRISPR gene<br />

editing. “But the market will tell<br />

youifit’svaluable.”<br />

Such efforts to design synthetic<br />

life forms are often referred to<br />

as playing God, and frequently<br />

raise fears about their possible<br />

impact on the environment and<br />

human health. “If we’re already<br />

playing God, we’re not doing a<br />

particularly good job of it,” Elfick<br />

says. “Simply streamlining what’s<br />

already in nature doesn’t seem<br />

very God-like and, if anything, is<br />

a very humbling exercise.”<br />

He says we should not worry<br />

about this synthetic cell: “There<br />

are plenty of bugs already out<br />

there we should be much more<br />

worried about.” ■<br />

FEDERICO DE LUCA<br />

ONE MINUTE INTERVIEW<br />

Tiny but mighty<br />

A bacterium that can thrive with the smallest feasible string of<br />

synthetic genes is no vanity project, says Richard Kitney<br />

PROFILE<br />

Richard Kitney is a professor of biomedical<br />

systems engineering at Imperial College London,<br />

and co-director of the Centre for Synthetic<br />

Biology and Innovation. He was not involved<br />

in Craig Venter’s research<br />

What is the main advance with the creation of<br />

the smallest synthetic genome, JCVI-syn3.0?<br />

What Craig Venter’s team has done in making this<br />

minimal genome is to identify clear gaps in our<br />

knowledge about what makes a cell survive. They<br />

have essentially removed sections of the genome<br />

one by one to see what happens – in other words,<br />

to see if it dies and to try and understand why.<br />

What new insights has the bacterium given<br />

about life’s minimum requirements?<br />

The failure of a predecessor organism with even<br />

fewer genes led to the refinement of the rules for<br />

designing a genome, and identified a group of<br />

indispensable genes with functions we now need<br />

to investigate.<br />

What do you make of the fact that almost a<br />

third of the genes in syn3.0 have no known<br />

function, yet seem essential to life? What might<br />

they be doing?<br />

This is partially because of the incomplete state of<br />

knowledge within the field. As Venter’s team also<br />

points out, the tools used to match genes in syn3.0’s<br />

genome to comparable ones with known functions<br />

in other organisms may have failed to identify<br />

some genes because their sequences differ too<br />

much. It is of course an intriguing question as to<br />

what any unidentified genes do.<br />

Does the fact that Venter borrowed the<br />

“shell” of a different organism as a host and<br />

provided a perfect environment for growth<br />

detract from his achievement?<br />

Borrowing the shell of a naturally occurring<br />

bacterium is of course a major simplification of the<br />

technical challenge of making a synthetic organism.<br />

But it did allow the team to concentrate on the<br />

problem of genome minimisation–averylarge<br />

endeavour on its own. Because the researchers<br />

chose a rich growth medium, they could snip out<br />

many functions from the original host, as these<br />

are not needed when food is plentiful. What all<br />

this highlights is that there is in fact no universal<br />

minimal cell, only a minimal cell for a given set<br />

of conditions.<br />

Does the work offer clues about how<br />

life began?<br />

No, it tells us nothing about how life started<br />

naturally.<br />

There has been criticism that such work is<br />

a vanity project with no real scientific worth.<br />

Do you agree?<br />

Venter and his colleagues are serious researchers<br />

who are pursuing an important goal, so this is<br />

absolutely not a vanity project. It is an important<br />

step towards meeting synthetic biology’s need<br />

for stable, well-understood host cells that make<br />

and do useful things for us.<br />

Does it take us closer towards creating<br />

living organisms from scratch?<br />

This is not really a step forward in that sense.<br />

And where will the work go next?<br />

What is clear is that the host genome as<br />

presented has quite a way to go in terms of<br />

extending the catalogue of usable organisms<br />

available for synthetic biology.<br />

Interview by Andy Coghlan<br />

2 April 2016 | NewScientist | 7


THIS WEEK<br />

LYNN HILTON/ALAMY STOCK PHOTO<br />

Did a cosmic cloud<br />

kill off the dinos?<br />

Shannon Hall<br />

A NEBULAR winter could have<br />

doomed the dinosaurs. The clue is<br />

a thick layer of an extraterrestrial<br />

element on the ocean floor, now<br />

claimed to be the result of Earth<br />

colliding with a galactic cloud.<br />

The most-heard explanation<br />

for the dinosaurs’ demise is an<br />

asteroid impact, which left a<br />

crater off the coast of Mexico and<br />

a worldwide 30-centimetre-thick<br />

layer of iridium, an element<br />

otherwise rare on Earth.<br />

But every so often, astronomers<br />

suspect, the solar system ploughs<br />

into a giant nebula of molecular<br />

gas and dust much denser than<br />

typical interstellar space. The<br />

resulting galactic fog would have<br />

darkened skies and cooled the<br />

ground until a harsh winter set<br />

in. It would also have destroyed<br />

the ozone layer and halted<br />

photosynthesis.<br />

Now Tokuhiro Nimura of the<br />

Japan Spaceguard Association in<br />

Ibara and colleagues claim such<br />

a collision could have ended the<br />

dinosaurs’150-million-year reign.<br />

At a site in the Pacific Ocean, the<br />

team found an iridium-rich<br />

sediment layer 5 metres thick,<br />

too thick for a sudden event like<br />

an asteroid strike to account for it.<br />

They argue that a collision with<br />

a giant molecular cloud – which<br />

could take Earth at least a million<br />

years to pass through, picking<br />

up iridium steadily as it does so –<br />

fits the discovery much better.<br />

“Such an encounter and related<br />

perturbation in global climate [is]<br />

a more plausible explanation for<br />

the mass extinction than a single<br />

impact event,” they write (arxiv.<br />

org/abs/1603.06136).<br />

Adrian Melott at the University<br />

–No escaping this winter–<br />

of Kansas in Lawrence says the<br />

idea is wacky but not impossible.<br />

“We know that these clouds exist,”<br />

he says. “We know that we’re likely<br />

to run into one sooner or later.<br />

And they have some evidence<br />

from the ocean floor in favour of<br />

their idea.”<br />

Others question that evidence.<br />

David Kring at the Lunar and<br />

Planetary Institute in Houston,<br />

Texas, argues that the deposit<br />

could have been disturbed by<br />

currents, organisms and drilling,<br />

broadening the layer locally.<br />

“There have been several<br />

studies specifically designed to<br />

determine the thickness of the<br />

iridium anomaly,” he says. “They<br />

all indicate the anomaly is sharp,<br />

not broad,” which would favour<br />

the impact hypothesis.<br />

Even so, a collision with a cloud<br />

could have dislodged rocks from<br />

the fringes of the solar system and<br />

sent them hurtling toward Earth –<br />

perhaps explaining the crater and<br />

leaving a thin iridium layer intact.<br />

We could test this idea by<br />

searching the ocean floor for<br />

radioactive elements likely to<br />

be replenished from space, like<br />

uranium and plutonium, says<br />

Alexander Pavlov at NASA’s<br />

Goddard Space Flight Center in<br />

Maryland. Most uranium isotopes<br />

aren’t even found in the solar<br />

system, so finding them along<br />

with iridium would prove that<br />

something interstellar, like a vast<br />

nebula, was the true culprit. ■<br />

Asteroid shower<br />

brought a sea to<br />

young, dry Mars<br />

MARS may once have had an ocean –<br />

but only for a geological eye blink.<br />

This puts a dampener on ideas that<br />

there is or was life on the Red Planet.<br />

That’s according to a theory from<br />

Tim Parker of NASA’s Jet Propulsion<br />

Laboratory in Pasadena, California.<br />

Speaking at the Lunar and Planetary<br />

Science Conference in The Woodlands,<br />

Texas, in March, he argued that a<br />

sustained barrage of asteroids hitting<br />

the young Mars could have delivered<br />

short-lived water to the surface.<br />

Signs that Mars was once rife with<br />

water litter the surface. These include<br />

polygonal cracks seen by NASA’s<br />

Opportunity rover. On Earth, these<br />

require evaporation to form, so Parker<br />

sees them as an indication that the<br />

rover is traversing what was once the<br />

edge of an ocean. “The uniformity of<br />

the surface is much easier to explain<br />

in a shallow marine setting,” he says.<br />

But models of the ancient Mars<br />

climate require a thicker atmosphere<br />

to keep water liquid on the surface.<br />

This atmosphere must have somehow<br />

been rapidly lost to leave Mars as dry<br />

as we see it today.<br />

Now Parker and his colleagues say a<br />

tumultuous time in the solar system’s<br />

history known as the late heavy<br />

bombardment could provide the water<br />

with no need for a major change in the<br />

atmosphere. During this period about<br />

4 billion years ago, a barrage of<br />

asteroids is thought to have collided<br />

“This ocean would have<br />

frozen and disappeared –<br />

leavingverylittletimefor<br />

life to evolve”<br />

with the inner planets. Such asteroids<br />

could have brought water to an<br />

initially dry Mars, says Parker.<br />

Because Mars’s atmosphere<br />

was so thin, this ocean would have<br />

frozen and disappeared after just a<br />

few hundred million years – allowing<br />

very little time for life to evolve.<br />

“Tim is always thinking outside<br />

of the box,” says Devon Burr of the<br />

University of Tennessee, Knoxville.<br />

“There are a variety of ways of<br />

warming Mars and getting liquid<br />

water, I don’t know if the late heavy<br />

bombardment, for me, is conclusive.”<br />

Jacob Aron ■<br />

8 | NewScientist | 2 April 2016


For daily news stories, visit newscientist.com/news<br />

JOHN HOOGLAND<br />

Prairie dogs are<br />

serial killers of<br />

ground squirrel<br />

IT WAS thought to be just a small,<br />

furry grass-nibbler, but the whitetailed<br />

prairie dog has another life – as<br />

a serial killer. Some prairie dogs bite<br />

their ground squirrel neighbours to<br />

death on a regular basis, the first time<br />

that a mammalian herbivore has been<br />

seen killing other herbivores.<br />

What’s more, those who kill go on<br />

to produce more surviving offspring,<br />

improving their evolutionary fitness,<br />

say John Hoogland, a biologist at the<br />

University of Maryland Center for<br />

Environmental Science, and Charles<br />

Brown of the University of Tulsa,<br />

Oklahoma. The duo recorded<br />

163 killings of the squirrels over<br />

six years in the Arapaho National<br />

Wildlife Refuge in Colorado.<br />

Hoogland describes the killings<br />

as quick, subtle and unanticipated.<br />

While some prairie dogs chased the<br />

squirrels, others stalked them, waited<br />

outside their burrows or even dug<br />

babies out of their holes. They bit<br />

them to death, then abandoned<br />

the carcass and resumed foraging<br />

on nearby vegetation. “The killer<br />

supreme killed seven babies from the<br />

same litter in one day,” says Hoogland.<br />

Over the six years, about 47 prairie<br />

dogs killed squirrels, and 19 of<br />

them were serial slayers, including<br />

one female who dispatched nine<br />

squirrels over four years (Proceedings<br />

of the Royal Society B, doi.org/bdpv).<br />

For squirrels a competitor species<br />

can be as much of a risk as a predator.<br />

Aisling Irwin ■<br />

–Not going to eat that...–<br />

BRAND NEW IMAGES/GETTY<br />

‘Fearless’ twins show<br />

body affects emotions<br />

IS FEAR all in the mind – or body?<br />

Experiments on twins who can’t<br />

feel fear are suggesting that some<br />

emotions rely on us becoming<br />

aware of changes to our body.<br />

Many studies have shown that<br />

the amygdalae, two almondshaped<br />

structures in our brain,<br />

are crucial for feeling fear. People<br />

who have lost them through<br />

injury or disease also lose the<br />

ability to feel most kinds of fear.<br />

In 2013, Justin Feinstein, then<br />

at the University of Iowa in Iowa<br />

City, and his colleagues managed<br />

to scare three“fearless”people –<br />

two female identical twins and<br />

a woman known as S. M., all of<br />

whom had had their amygdalae<br />

destroyed by illness. Feinstein<br />

made them inhale carbon dioxide,<br />

giving them the sensation of<br />

choking. This was the first time<br />

that S. M. had experienced fear<br />

since she was a child. It showed<br />

that the amygdalae are not<br />

essential for all kinds of fear.<br />

One theory of emotion suggests<br />

that feelings are not generated<br />

directly by the brain, but through<br />

an awareness of our body. When<br />

–In tune with their body state–<br />

we see a spider, for example,<br />

the theory says we feel fear not<br />

because emotional centres of<br />

the brain are activated, but<br />

because the brain evaluates the<br />

situation and releases hormones<br />

such as adrenaline that increase<br />

“This seems to be evidence<br />

that extreme panic has<br />

different circuitry from<br />

normal fear”<br />

our heart rate and give us sweaty<br />

palms. It is our awareness of<br />

these changes to our body that<br />

we interpret as fear.<br />

Now Feinstein’s colleague<br />

Sahib Khalsa, at the University<br />

of Tulsa, Oklahoma, and his team<br />

have given the fearless twins a<br />

drug that mimics the action of<br />

adrenaline. High levels of this<br />

drug can cause temporary<br />

breathing difficulties and rapid<br />

heart palpitations. The team<br />

asked the twins and a group of<br />

volunteers with intact amygdalae<br />

to rate their experience of these<br />

changes on a scale from 0 to 10.<br />

Both twins had the same<br />

physical reaction as the other<br />

volunteers – their heart and<br />

breathing rates increased. But<br />

only one twin said she was aware<br />

of both these changes, rating her<br />

breathing problems as a 10 on the<br />

scale. She also reported a choking<br />

sensation and had a panic attack.<br />

The volunteers also noted<br />

breathing difficulties and a<br />

quarter had panic attacks.<br />

The other twin noted a slight<br />

awareness of her heart rate<br />

changing, but she rated her<br />

physical symptoms as close<br />

to zero and did not panic.<br />

The results indicate that<br />

there are mechanisms beyond<br />

the amygdalae that are involved<br />

in fear and anxiety, and support<br />

the theory that an awareness of<br />

physiological changes may be<br />

necessary to experience some<br />

kinds of emotion (The Journal<br />

of Neuroscience, doi.org/bdpz).<br />

However, the fact that the<br />

twins – who both have damaged<br />

amygdalae because of a rare<br />

genetic condition – had different<br />

responses suggests there may be<br />

environmental factors at play, too.<br />

“This seems to be more evidence<br />

that extreme panic has its own<br />

underlying circuitry that is<br />

different from normal fear,”<br />

says Nick Medford, who studies<br />

consciousness and emotion at the<br />

Sackler Centre for Consciousness<br />

Science in Brighton, UK.<br />

Further experiments involving<br />

scanning the twins’ brains while<br />

they experience fear would help<br />

us identify mechanisms of<br />

emotion in the brain, says Khalsa.<br />

Such studies could also lead to<br />

alternative treatments for anxiety<br />

disorders. There is some evidence<br />

to suggest that people who have<br />

abnormal awareness of their<br />

bodily functions are more prone<br />

to anxiety and depression.<br />

“If you could pinpoint neural<br />

regions responsible for our<br />

awareness of our body state and<br />

the different mechanisms that<br />

generate fearful feelings, you<br />

might have new targets to<br />

modulate or reduce anxiety,”<br />

says Khalsa. Helen Thomson ■<br />

2 April 2016 | NewScientist | 9


THIS WEEK<br />

Emissions reveal<br />

a constructive side<br />

Richard Schiffman<br />

TAKING carbon dioxide out of the<br />

atmosphere is crucial to slowing<br />

the progress of climate change.<br />

But rather than lock all that CO 2<br />

away underground, what if we<br />

could use it to make things?<br />

That’s the aim of a pilot plant<br />

at the University of Newcastle<br />

near Sydney, Australia.<br />

Launched last week, the plant<br />

will test the commercial potential<br />

of mineral carbonation, a process<br />

that forms stable materials by<br />

chemically binding CO 2<br />

to<br />

minerals containing calcium or<br />

magnesium. The plant will bind<br />

the gas into crushed serpentinite<br />

rocks to create magnesium<br />

carbonate, which can be used to<br />

produce cement, paving stones<br />

and plasterboard.<br />

It could be a way of<br />

“permanently and safely<br />

disposing of CO 2<br />

and making<br />

useful products in the process”,<br />

says Klaus Lackner of Arizona<br />

State University in Tempe,<br />

who pioneered the technique<br />

in the lab.<br />

The process happens naturally<br />

when rocks are gradually<br />

MINERAL CARBONATION INTERNATIONAL<br />

weathered by exposure to CO 2<br />

in the air. This helped cut the<br />

proportion of the gas in the<br />

ancient atmosphere to levels<br />

low enough for life to flourish,<br />

says Geoff Brent, senior<br />

scientist at Orica, an explosives<br />

– Made with greenhouse gases–<br />

manufacturer based in Melbourne.<br />

His firm is supplying the plant<br />

with CO 2<br />

– a by-product of making<br />

ammonium nitrate.<br />

But we can’t afford to wait<br />

millions of years for geology<br />

to rid the atmosphere of our<br />

greenhouse emissions. “It’s about<br />

turning the natural process into<br />

a large-scale industrial process<br />

on our required timescale – which<br />

is extremely urgent,” says Brent.<br />

There are several challenges.<br />

Mining for serpentinite is energyintensive<br />

and damaging to the<br />

environment, for one thing.<br />

But Brent says the rock is one of<br />

the most common on Earth, and<br />

that carbonation plants could<br />

be built near mining areas to<br />

reduce transport emissions.<br />

Another objection is that<br />

mineral carbonation costs too<br />

much compared with storing<br />

CO 2<br />

underground. However,<br />

underground storage has its own<br />

problems: suitable repositories<br />

are hard to find and there is a risk<br />

that the gas may one day escape.<br />

“Carbonation is more secure in<br />

the long term, because there is no<br />

danger of leakage and no need to<br />

maintain long gas pipelines and<br />

transportation infrastructure to<br />

move the CO 2<br />

, since we will be<br />

obtaining it on-site,” says Brent.<br />

“The whole point of the<br />

project is to get the price down<br />

low enough,” says Marcus Dawe,<br />

CEO of Mineral Carbonation<br />

International, the firm<br />

coordinating the effort. “It is<br />

all about how we can make<br />

this economical.”<br />

Dawe and his team are<br />

optimistic that they will make<br />

progress by the end of the 18-<br />

month pilot project. But for<br />

mineral carbonation to take off,<br />

there will need to be a higher<br />

price on carbon, says Dawe,<br />

because right now “nothing is<br />

more economical than putting<br />

CO 2<br />

in the air”. ■<br />

Is calcium boost<br />

behind brain<br />

zap effects?<br />

WE MAY finally be figuring out how<br />

an increasingly popular therapy that<br />

uses electricity to boost the brain’s<br />

functioning has its effects – by<br />

pushing up levels of calcium in cells.<br />

Transcranial direct current<br />

stimulation (tDCS) has been linked to<br />

effects such as accelerated learning<br />

and improving the symptoms of<br />

depression. It involves using<br />

electrodes to send a weak current<br />

across the brain, which proponents<br />

think changes the electrical<br />

properties of neurons, leading<br />

to changes in their connectivity.<br />

But the cellular mechanisms that<br />

lead to such broad neurological<br />

changes are not clear and some are<br />

doubtful that tDCS has any effect on<br />

the brain. Despite this, devices are<br />

being developed to sell to people<br />

keen to influence their own brains.<br />

Now Hajime Hirase at the RIKEN<br />

Brain Science Institute in Tokyo,<br />

Japan, and his colleagues have an<br />

answer. They have identified sudden<br />

surges in calcium flow in the brains of<br />

mice seconds after they receive low<br />

doses of tDCS. The surges start in<br />

star-shaped cells called astrocytes<br />

that strengthen connections between<br />

neurons and regulate the electrical<br />

signals that pass between them.<br />

The team used mice that had been<br />

engineered to show depression-like<br />

symptoms, such as struggling less<br />

against restraints. After they had<br />

received tDCS, the mice struggled<br />

for longer. The same effect didn’t<br />

happen in mice whose calcium<br />

“By triggering calcium<br />

surges, tDCS may<br />

be interfering with<br />

neuron connectivity”<br />

signalling had been disabled (Nature<br />

Communications, doi.org/bdr2).<br />

Astrocytes use calcium to manage<br />

the flow of information between<br />

neurons, and these findings suggest<br />

that tDCS artificially boosts the<br />

process. Hirase thinks calcium<br />

signalling may also be behind other<br />

suggested effects of tDCS, such as<br />

improved memory.<br />

Understanding the link between<br />

tDCS and calcium could dispel doubts<br />

about the technique. “Scepticism is<br />

not so much about tDCS itself as it is<br />

about inflated expectations,” says<br />

Walter Paulus of the University of<br />

Göttingen in Germany. Sally Adee ■<br />

10 | NewScientist | 2 April 2016


F<br />

I<br />

N<br />

Subscribe now for less than $2 per week,<br />

and discover a whole world of new ideas<br />

and inspiration<br />

Visit newscientist.com/8823 or call<br />

1-888-822-3242 and quote offer 8823<br />

#LiveSmarter<br />

CYRUS CORNUT/DOLCE VITA/PICTURETANK


THIS WEEK<br />

NASA/JPL-CALTECH/UCLA/MPS/DLR/IDA/PSI/LPI<br />

Bright spots and<br />

ice dazzle on Ceres<br />

Jacob Aron, The Woodlands, Texas<br />

LET’S take a look inside. The latest<br />

from NASA’s Dawn probe, which<br />

has been in orbit around the dwarf<br />

planet Ceres since April last year,<br />

suggests this tiny world has water<br />

ice on the surface and craters that<br />

provide a window on its interior.<br />

A spectacular view of the<br />

beguiling bright spots at the heart<br />

of the 92-kilometre-wide Occator<br />

crater from just 375 kilometres up,<br />

shown above, was just one of the<br />

latest findings unveiled by the<br />

mission team at the Lunar and<br />

Planetary Science Conference<br />

in The Woodlands, Texas, on<br />

22 March.<br />

These spots have perplexed<br />

researchers since Dawn first<br />

reached Ceres, the largest object<br />

in the asteroid belt. Probing their<br />

nature could give clues to Ceres’s<br />

interior. In the new image, Dawn<br />

has seen colour variations across<br />

the surface of the bright regions.<br />

These wouldn’t be visible to the<br />

human eye, but reflect possible<br />

differences in the composition<br />

of the material seen by Dawn.<br />

This close-in view reveals that<br />

the central bright spot actually<br />

sits within a 10-kilometre-wide<br />

depression inside the crater.<br />

At the centre of that is a small<br />

mound. “We’re starting to see<br />

how complex the distribution of<br />

the bright material is,” said Carol<br />

Raymond of NASA’s Jet Propulsion<br />

Laboratory in California.<br />

How this arrangement formed<br />

is still a mystery. Timothy Bowling<br />

at the University of Chicago<br />

presented a possible explanation,<br />

“Seeing water ice anywhere<br />

on Ceres is a surprise – it<br />

is warm enough at the<br />

surface for it to evaporate”<br />

in which a meteorite smacked<br />

into Ceres, exposing icy material<br />

from as much as 40 kilometres<br />

below the surface and heating it up.<br />

As this material settled into the<br />

Occator crater we see today, the<br />

water would evaporate, leaving<br />

bright salt and minerals behind.<br />

The floor of Occator is also<br />

riddled with fractures that<br />

seem to be older than the crater<br />

itself. These could have provided<br />

an escape route for material<br />

How to stack<br />

oranges in 24<br />

dimensions<br />

IT’S a tight squeeze. Mathematicians<br />

have proved that they know the<br />

best way to pack spheres in eight<br />

and 24 dimensions – the first time<br />

this problem has been solved in a<br />

new dimension for almost 20 years.<br />

“I think they’re fantastic results. I’m<br />

excited that this has been done at last,”<br />

says Thomas Hales at the University<br />

of Pittsburgh, Pennsylvania.<br />

The sphere-packing problem asks<br />

a deceptively simple question: what<br />

–Beguiling brightness– arrangement crams the most spheres<br />

into a limited volume? It is easy to<br />

beneath the surface.<br />

describe, but difficult to prove.<br />

The team behind Dawn has also In 1611, Johannes Kepler suggested<br />

made an unexpected discovery: that the best arrangement for<br />

water ice hiding in a crater. The 3-dimensional spheres like oranges<br />

10-kilometre-wide Oxo crater is a pyramid. But it took until 1998<br />

seems to have formed relatively for Hales to publish a proof – and<br />

recently. The find comes from another 16 years to formally verify it.<br />

spectral data taken during Dawn’s Meanwhile, mathematicians have<br />

higher orbit in June last year.<br />

been gunning for higher dimensions.<br />

Seeing water ice anywhere on Now, Maryna Viazovska at Humboldt<br />

Ceres is a surprise as it is warm University of Berlin has proved that<br />

enough at the surface for any<br />

a grid called the E8 lattice is the best<br />

ice to evaporate into space. That packing in eight dimensions (arxiv.<br />

means it must have been exposed org/abs/1603.04246v1). Almost<br />

recently, said Jean-Philippe<br />

immediately after, she teamed up<br />

Combe of the Bear Fight Institute with other researchers to prove that<br />

in Winthrop, Washington. “This a related arrangement called the<br />

area is possibly a cold trap where Leech lattice is best in 24 dimensions<br />

H 2<br />

0-rich materials could be<br />

(arxiv.org/abs/1603.06518v1).<br />

preserved for at least some time,” The fact that these dimensions<br />

he said.<br />

were next to fall is no coincidence.<br />

So where has this water<br />

For reasons we don’t understand,<br />

come from? Models of Ceres’s such lattices don’t show up in other<br />

formation, along with the<br />

dimensions. But they were suspected<br />

sightings of bright spots like the to be the most efficient arrangements<br />

ones at Occator, suggest the dwarf in the dimensions they apply to.<br />

planet has an icy sub-surface layer “These are unbelievably good<br />

that is mixed up with salt and packings,” says Henry Cohn at<br />

rock. The ice at Oxo could have Microsoft Research New England in<br />

been exposed by a landslide,<br />

Cambridge, Massachusetts. “The<br />

or dug up by a meteorite.<br />

spheres in these dimensions fit<br />

Dawn will continue to gather perfectly, in ways that don’t happen<br />

data about Ceres until August at in other dimensions.”<br />

least, and possibly into next year. Packing spheres in 24 dimensions<br />

But some questions about this isn’t just a mathematical game. The<br />

enigmatic world may not<br />

problem has applications in wireless<br />

be answered until a repeat visit. communication, and has been used to<br />

“It would be nice to land there, communicate with spacecraft in the<br />

wouldn’t it?” said Raymond. ■ distant solar system. Lisa Grossman ■<br />

12 | NewScientist | 2 April 2016


Cognitive Behavioral<br />

Therapy: Techniques for<br />

Retraining Your Brain<br />

Conquer Your Bad<br />

Thoughts and Habits<br />

70%<br />

LIMITED TIME OFFER<br />

off<br />

ORDER BY APRIL 12<br />

Why is it so hard to lose weight, stop smoking, or establish healthy<br />

habits? Why do couples argue about the same issues over and over? Why<br />

do so many people lie awake at night, stricken with worry and anxiety?<br />

The answers to these questions—and the path to lasting change in your<br />

life—lie in cognitive behavioral therapy (CBT). Developed on a proven<br />

foundation of neurological and behavioral research, CBT is a welltested<br />

collection of practical techniques for managing goal-oriented<br />

change. Build a toolkit of CBT techniques as you to take on the role of<br />

medical student, physician, psychologist, and patient, and learn how to<br />

create lasting change in your life.<br />

Offer expires 04/12/16<br />

<strong>THE</strong>GREATCOURSES.COM/4NSUSA<br />

1-800-832-2412<br />

Taught by Professor Jason M. Satterfield<br />

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO<br />

LECTURE TITLES<br />

1. Cognitive Behavioral Foundations<br />

2. Quantified Self-Assessment for Therapy<br />

3. Setting Therapeutic Goals<br />

4. Third-Wave Cognitive Behavioral Therapy<br />

5. Stress and Coping<br />

6. Anxiety and Fear<br />

7. Treating Depression<br />

8. Anger and Rage<br />

9. Advanced Cognitive Behavioral Therapy<br />

10. Positive Psychology<br />

11. Healing Traumatic Injuries<br />

12. Forgiveness and Letting Go<br />

13. Digging Deep and Finding Meaning<br />

14. Cognitive Behavioral<br />

Therapy and Medicine<br />

15. Staying on the Wagon<br />

16. Thinking Healthy: Weight and Nutrition<br />

17. Behavioral Therapy for<br />

Chemical Addictions<br />

18. Getting a Good Night’s Sleep<br />

19. Mastering Chronic Pain<br />

20. Building and Deepening Relationships<br />

21. Constructive Conflict and Fighting Fair<br />

22. Thriving at Work through<br />

Behavioral Health<br />

23. Developing Emotional Flexibility<br />

24. Finding the Best Help<br />

Cognitive Behavioral Therapy:<br />

Techniques for Retraining Your Brain<br />

Course no. 9631 | 24 lectures (30 minutes/lecture)<br />

SAVE UP TO $190<br />

DVD $269.95 NOW $79.95<br />

CD $199.95 NOW $59.95<br />

+$10 Shipping, Processing, and Lifetime Satisfaction Guarantee<br />

Priority Code: 127962<br />

For over 25 years, The Great Courses has brought<br />

the world’s foremost educators to millions who<br />

want to go deeper into the subjects that matter<br />

most. No exams. No homework. Just a world of<br />

knowledge available anytime, anywhere. Download<br />

or stream to your laptop or PC, or use our free<br />

mobile apps for iPad, iPhone, or Android. Over 550<br />

courses available at www.TheGreatCourses.com.


LET YOUR LOVE LIFE LIFT OFF<br />

ON<br />

NEW SCIENTIST CONNECT<br />

Join now<br />

FOR<br />

FREE<br />

We all know it’s not rocket science trying to find that special<br />

someone with whom we connect, even though it sometimes feels<br />

that way. Which is why we’ve launched New Scientist Connect.<br />

Meet like-minded people who share similar interests to you –<br />

whether you’re looking for love, or just to meet someone on the<br />

same wavelength, no matter where you are in the world.<br />

Launch your search now at: http://dating.newscientist.com


IN BRIEF<br />

JOHN WATKINS/FLPA/CORBIS<br />

Migrating birds arrive in the<br />

UKearlierandleavelater<br />

SOME common migrating birds – including the blackcap,<br />

(pictured above) – are staying in the UK for two weeks<br />

or more longer than half a century ago. “We knew that<br />

birds were arriving earlier in spring, but this is the first<br />

study I know of in Europe that has also tracked when they<br />

leave in autumn,” says Stuart Newson of the British Trust<br />

for Ornithology.<br />

Newson has tapped into amateur observations of bird<br />

migrations collected over more than 50 years, starting<br />

with paper files in the 1960s and ending with 800,000<br />

records from BirdTrack, an internet-based volunteer<br />

Ghostgalaxiesarefullofdarkmatter<br />

<strong>THE</strong>RE’S more than meets the eye.<br />

A so-called ultra-diffuse galaxy<br />

has been found to consist of over<br />

99.96 per cent dark matter.<br />

An ultra-diffuse galaxy is a<br />

huge galaxy with relatively few<br />

stars widely spread out, so it looks<br />

ghostly and is hard to study.<br />

The fact that they hold their<br />

shape makes researchers think<br />

such galaxies must consist of at<br />

least 98 per cent dark matter – the<br />

stuff thought to make up about<br />

80 per cent of the mass in the<br />

universe overall. But no one<br />

had directly measured it.<br />

Now Michael Beasley at the<br />

Institute of Astrophysics of the<br />

Canary Islands, Spain, and his<br />

colleagues have “weighed” an<br />

ultra-diffuse galaxy in the<br />

Virgo cluster named VCC 1287.<br />

The team measured the speeds<br />

of seven globular star clusters<br />

observation network, to study 14 common migrating<br />

birds. He found that 11 species arrive earlier and four<br />

leave later (Ibis, doi.org/bdpr).<br />

Amateur data is best, he says. Professional<br />

ornithologists have mostly counted birds arriving at a<br />

handful of coastal observation points. And many previous<br />

studies concentrated on dating the first birds to arrive.<br />

Observations from citizen scientists avoid such biases,<br />

and cover leaving times too.<br />

One reason for late leaving could be that females are<br />

laying more than one clutch of eggs thanks to the longer<br />

breeding season, says Tim Sparks of Coventry University,<br />

UK. Indeed, the study also shows that birds taking most<br />

advantage of earlier springs and balmy late autumns,<br />

such as the blackcap, are increasing in number.<br />

orbiting the galaxy, a clue to how<br />

much mass it contains, and found<br />

that it must have about 80 billion<br />

times more mass than the sun<br />

and 3000 times more dark matter<br />

than stellar mass (Astrophysical<br />

Journal Letters, doi.org/bdpb).<br />

VCC 1287 was probably born<br />

with both dark matter and gas<br />

but lost the latter as it fell into<br />

the Virgo cluster. Without gas,<br />

it couldn’t create new stars, so it<br />

ended up with lots of dark matter<br />

but little light.<br />

Exercise keeps<br />

your brain younger<br />

YOUNG in body, young in mind.<br />

Older people who are physically<br />

active seem to stave off memory<br />

loss – but only if they start early.<br />

Clinton Wright at the University<br />

of Miami in Florida and his<br />

colleagues followed 876 people,<br />

starting at an average age of 71,<br />

over five years. At the end, the<br />

brains of non-exercisers looked<br />

10 years older than those who<br />

did moderate exercise. Those<br />

who exercised also showed<br />

less memory loss (Neurology,<br />

doi.org/bdpw).<br />

These effects are associated<br />

with better vascular health,<br />

suggesting that exercise helps<br />

the brain by keeping down blood<br />

pressure and preventing strokes.<br />

But the team’s results showed<br />

that physical activity can only<br />

delay memory loss if a person<br />

begins exercising before the<br />

onset of symptoms. “Once<br />

there’s damage, you can’t really<br />

reverse it,” says Wright.<br />

Why we have really<br />

big noses…<br />

IT’S an evolutionary mystery<br />

that’s literally as plain as the<br />

nose on your face. Why did our<br />

ancestors develop a prominent<br />

protruding nose when most<br />

primates have flat nasal openings?<br />

A new study suggests that our<br />

unusual nose may simply be a byproduct<br />

of other, more important<br />

changes in the structure of our<br />

face as our brains enlarged.<br />

Takeshi Nishimura at Kyoto<br />

University, Japan, and his team<br />

modelled the flow of inhaled air<br />

through the nasal passages of<br />

humans, chimpanzees and<br />

macaques. It turns out that our<br />

noses, unlike those of other<br />

primates, are poor at warming or<br />

cooling air that goes to the lungs<br />

(PLoS Computational Biology, DOI:<br />

10.1371/journal.pcbi.1004807).<br />

2 April 2016 | NewScientist | 15


IN BRIEF<br />

For new stories every day, visit newscientist.com/news<br />

E BRUN<br />

Leaded ink opens<br />

up ancient scrolls<br />

LEAD often gets a bad press. But its<br />

discovery in ancient Graeco-Roman<br />

ink could make it easier to read an<br />

early form of publishing – precious<br />

scrolls buried by the eruption of<br />

Mount Vesuvius in AD 79.<br />

Some 800 scrolls, part of the<br />

classical world’s best-surviving<br />

library, have tantalised scholars<br />

since they were unearthed in a<br />

villa in the ancient Roman city of<br />

Herculaneum in 1752. About 200<br />

are in such a delicate state that they<br />

have never been read. Unrolling the<br />

charred scrolls could destroy them,<br />

so people have been X-raying the<br />

bundles in the hopes of decoding<br />

the writing inside. But progress has<br />

been slow – it is difficult to detect<br />

the difference between the letters<br />

and the papyrus they are written on.<br />

Now physicist Vito Mocella of<br />

the Italian National Research Council<br />

and his colleagues have discovered<br />

lead in the ink on two Herculaneum<br />

papyri fragments held in the<br />

Institute of France in Paris. The<br />

presence of lead means that<br />

imaging techniques could be<br />

recalibrated to pick up the metal,<br />

something X-rays excel at (PNAS,<br />

doi.org/bdn5).<br />

“This really opens up the<br />

possibility of being able to read<br />

these scrolls,” says Graham Davis,<br />

at Queen Mary University of London.<br />

“If this is typical of this scroll or other<br />

scrolls, than that is very good news.”<br />

Violent pirouette spun off the moon’s water<br />

BALLET doesn’t suit everyone.<br />

Molten rock flowing beneath the<br />

moon’s crust billions of years ago<br />

shifted its spin axis by about six<br />

degrees. The pirouette could have<br />

cost the moon most of its water.<br />

We saw the first direct evidence<br />

of water on the moon in 2009,<br />

when a deliberately crashed<br />

satellite found hydrogen – a proxy<br />

for water – in a southern crater.<br />

There was more there than at the<br />

actual pole, a little more than five<br />

degrees away, says Matthew<br />

Siegler of the Planetary Science<br />

Institute in Tucson, Arizona.<br />

Fungi may help<br />

woodpeckers drill<br />

IF A red-cockaded woodpecker<br />

wants a home, it does more than<br />

just knock on wood – it takes some<br />

tiny helpers with it. It seems to<br />

carry spores of wood-rotting fungi<br />

to each new hole.<br />

Red-cockaded woodpeckers<br />

live in the pine forests of the<br />

south-eastern US, where they dig<br />

tree cavities to live in. Each family<br />

has cavities at different stages of<br />

construction. It’s no quick bodge<br />

job–aholecantakeyears to craft.<br />

Michelle Jusino of the US<br />

Forest Service Center for Forest<br />

Mycology Research in Wisconsin<br />

and her colleagues have found a<br />

wide range of fungal spores on the<br />

birds, including many that cause<br />

wood decay and are found in<br />

cavities that woodpeckers dig.<br />

To see whether the birds bring<br />

the fungi to the cavities, the team<br />

drilled holes in 60 trees, covering<br />

half with screens the woodpeckers<br />

can’t get through. After 26 months,<br />

accessible holes had fungal<br />

communities that were more<br />

similar to those found in natural<br />

woodpecker cavities than to<br />

inaccessible holes. This suggests<br />

the birds do disperse fungi,<br />

although any benefit to them is<br />

still unproven (Proceedings of the<br />

Royal Society B, doi.org/bdn7).<br />

While scrutinising maps of<br />

the lunar composition, Siegler<br />

noticed that the highest<br />

concentration of hydrogen at the<br />

north pole is also a few degrees<br />

away from the true pole, but in<br />

the opposite direction.<br />

“They are on exact opposite<br />

sides of the moon from each<br />

other. It’s as if you drew a line<br />

through the centre of the moon<br />

from those two points,” he says.<br />

This indicates that the moon’s<br />

polar axis used to follow that line,<br />

but shifted. Based on its direction,<br />

Siegler and his colleagues think<br />

Parasites, mew give me road rage<br />

CATS can make us angry. Scratching<br />

our furniture, waking us up – and<br />

giving us parasites that may cause<br />

explosive rage.<br />

Toxoplasma gondii is a parasite<br />

carried by cats that lives in the brains<br />

of as many as a third of all people<br />

worldwide. Now the parasite has<br />

been linked to a psychiatric condition<br />

involving disproportionate outbursts<br />

of aggression, like road rage.<br />

Emil Coccaro at the University of<br />

Chicago and his colleagues compared<br />

110 people with intermittent<br />

explosive disorder (IED) with people<br />

who have no psychiatric diagnosis.<br />

the shift was caused when lava<br />

flowing up from the lunar interior<br />

formed the Procellarum region.<br />

The volcanism would have<br />

changed the distribution of the<br />

moon’s mass, spinning it around<br />

(Nature, doi.org/bdn9).<br />

That pirouette could have cost<br />

the moon much of its water. When<br />

the poles shifted, frozen water<br />

would have been exposed to the<br />

sun and evaporated. That helps to<br />

explain why the moon is so dry,<br />

and suggests that much of the<br />

lunar water is leftover from early<br />

in its life.<br />

They found that people with IED<br />

were more than twice as likely to<br />

test positive for exposure to T. gondii.<br />

In both groups, those who tested<br />

positive tended to rank more highly<br />

in tests for aggression (Journal of<br />

Clinical Psychiatry, doi.org/bdpq).<br />

Coccaro thinks the parasite may<br />

be altering neurotransmitters in<br />

the brain. However, the correlation<br />

doesn’t necessarily mean that<br />

T. gondii is causing the explosive<br />

rage. Aggressive people may be<br />

less likely to wash their hands,<br />

making them more likely to catch<br />

the parasite, for example.<br />

NATALIE SHUTTLEWORTH/GETTY<br />

16 | NewScientist | 2 April 2016


See science<br />

everywhere<br />

Enjoy free sample<br />

issues within the app<br />

Download the<br />

New Scientist app today


TECHNOLOGY<br />

Getdeepinthegame<br />

After years of hype, the moment is finally here. Douglas Heaven introduces<br />

the games that will kick-start the VR revolution<br />

CHESNOT/GETTY<br />

WHEN a small company called<br />

Oculus announced that it was<br />

building a virtual reality headset<br />

in 2012, it sent expectations<br />

soaring. The hope was for a device<br />

that might finally deliver on<br />

the promise of VR – which had<br />

become the butt of jokes after a<br />

run of false starts in the 1980s and<br />

90s. The moment of truth will<br />

arrive this week, when the Oculus<br />

Rift launches – along with a few<br />

dozen games that aim to kick-start<br />

the VR gaming revolution.<br />

The line-up includes games that<br />

let you conquer Everest, repair an<br />

orbiting space station and even<br />

take part in a ballet. One, Job<br />

Simulator, even puts you in a<br />

world where robots have replaced<br />

human workers and simulations<br />

are the only way to experience a<br />

life of nine-to-five employment.<br />

The Rift, which launches on<br />

28 March, will be joined on 5 April<br />

by the Vive, made by HTC and<br />

Valve. Sony’s Playstation VR<br />

system is due in October. And<br />

earlier this month, Canadian<br />

start-up Sulon revealed yet another<br />

rival headset,coming this Spring.<br />

Few technologies have been so<br />

hotly anticipated. But what will<br />

people make of them? The success<br />

of VR rests on the types of<br />

experiences it will offer. Many<br />

are versions of existing games<br />

that have been adapted to VR.<br />

For example, the view from your<br />

cockpit when travelling between<br />

stars in Elite Dangerous will now<br />

be more overwhelming than ever.<br />

But it is the games developed<br />

specifically for VR that could<br />

change the way we play. As well as<br />

the headset, VR games often make<br />

use of controllers that track your<br />

movements. These let you treat<br />

a controller as a gun – pointing it<br />

to aim as you would a real one – or<br />

as a rope that you have to grip to<br />

climb a rock face, or a basketball<br />

you have to slam dunk. Motion<br />

controllers themselves are not<br />

new, but their greater sensitivity<br />

combined with the full<br />

immersion of a headset that<br />

covers your eyes and ears leads<br />

to extremely vivid experiences.<br />

It sounds obvious, but what<br />

virtual reality lets us do is make<br />

the virtual a reality, says VR<br />

developer Xárene Eskandar at the<br />

University of California, Santa<br />

Barbara. “You are present more<br />

than with any other medium.<br />

It has your full attention.”<br />

But a big challenge facing the VR<br />

“We’re actually a bit thrilled<br />

that The Brookhaven<br />

Experiment might be too<br />

scary for some players”<br />

industry is describing what that is<br />

like to those who have not tried it.<br />

“It is almost impossible to convey<br />

the experience through any<br />

medium other than VR,” says Alex<br />

Knoll, co-founder of game studio<br />

Stress Level Zero, based in LA.<br />

It’s like trying to sell a colour TV<br />

in a world where only black and<br />

white TVs exist, says Steve Bowler<br />

at Phosphor Games in Chicago,<br />

which has made VR horror game<br />

The Brookhaven Experiment.<br />

“We have to get you in the virtual<br />

world with the headset on your<br />

face before you believe us that<br />

it’s amazing.”<br />

Game makers have had to<br />

overcome more practical issues<br />

too. One is how to give players a<br />

sense of freedom and movement<br />

when playing in their living room.<br />

Tripping over furniture and<br />

bumping into walls in one reality<br />

while you are saving the world – or<br />

flipping burgers – in another can<br />

quickly break the spell. A<br />

wireframe showing where the<br />

edges of a room are can be<br />

superimposed over the virtual<br />

world to stop you hurting<br />

yourself. But most games also give<br />

you reasons not to move around<br />

too much. For example, in Stress<br />

Level Zero’s Hover Junkers, a game<br />

–Is it my turn yet?– where you fight on hovercraft,<br />

18 | NewScientist | 2 April 2016


For more technology stories, visit newscientist.com/technology<br />

players are advised to choose a<br />

ship that is roughly the same size<br />

as the room they’re playing in.<br />

In other games, players stand in<br />

one spot and move around in the<br />

game by teleporting, for example.<br />

This also partly addresses the<br />

problem of motion sickness that<br />

many people experienced with<br />

VR software. Games have several<br />

other tricks to deal with this too.<br />

In Hover Junkers, the ships hover<br />

so there is very little bouncing,<br />

creating less conflict between<br />

what you see in the virtual world<br />

and what you feel in the real one.<br />

The ships also do not turn unless<br />

the player twists their body.<br />

Even standing still, there is a lot<br />

of opportunity for visceral action.<br />

In The Brookhaven Experiment<br />

players stand their ground against<br />

waves of monsters. Because the<br />

experience is so realistic, players<br />

reflexively step backwards when<br />

confronted, turn away and shield<br />

their face when hit, or lash out<br />

with their hands in defence.<br />

A handful of players have<br />

stopped playing because it is too<br />

frightening. For Bowler this is a<br />

sign of success. “We’re actually a<br />

bit thrilled that The Brookhaven<br />

Experiment might be too scary for<br />

some players.”<br />

Although nascent, the potential<br />

of consumer VR is clear. The<br />

best experiences do not simply<br />

try to adapt the conventions<br />

of screen-based media, says<br />

Eskandar. Using VR just to display<br />

360° video is pointless, she says.<br />

“It’s just a flat screen wrapped<br />

around your head.”<br />

Eskandar is developing a<br />

VR puzzle game called The<br />

Clocksmith’s Labyrinth. She<br />

thinks that by separating us from<br />

the physical constraints of one<br />

reality, VR experiences could<br />

ultimately give us fresh ways of<br />

conceptualising things.<br />

“I’m curious to see how humans<br />

will evolve with this medium,” says<br />

Eskandar. “My dream is that 20 to<br />

30 years down the road, one of the<br />

kids who has played these games<br />

can solve a cosmological puzzle<br />

that finds the multiverse.” ■<br />

<strong>THE</strong> BROOKHAVEN EXPERIMENT<br />

A horror game in which you must survive an<br />

onslaught from hordes of monsters. Danger<br />

approaches from all sides, so you have to keep<br />

looking over your shoulder. Armed with a pistol<br />

and a limited supply of bullets, every shot counts.<br />

But as the tension mounts, your aim waivers.<br />

Unlike most games, you fire with a motion<br />

controller held like a gun, rather than a mouse or<br />

joystick. The experience is realistic enough that<br />

the developers say they can tell which players<br />

know how to use a real gun.<br />

JOB SIMULATOR<br />

Office job getting you down? Now you can<br />

escape into a simulation of a simulation of a<br />

different one. In this game, all jobs have been<br />

taken by robots. To keep themselves amused,<br />

humans have developed simulations of what<br />

it was like to be an employee in the good old<br />

days – cooking in a restaurant kitchen, sitting at<br />

a supermarket checkout, keeping busy in an office<br />

cubicle. Largely an excuse to have fun interacting<br />

with virtual versions of everyday objects, the<br />

game is a lot more enjoyable than it sounds.<br />

<strong>THE</strong> CLIMB<br />

A hundred metres up, the boats in the beautiful<br />

bay look like toys. Your eyes are fixed on the next<br />

ledge, however. You cling to the rock face by<br />

squeezing the triggers on two motion controllers<br />

held in each hand, and move to the next hand-hold<br />

by looking in its direction and reaching for it. As you<br />

climb, you also have to stop to reapply chalk as your<br />

character’s hands get sweaty. Sometimes the only<br />

way to proceed is to leap, which is guaranteed to<br />

get the heart pumping. Players compete for fastest<br />

ascents or can watch others tackle tricky climbs.<br />

TILT BRUSH<br />

When you’re done with role-playing and just feel<br />

like doodling, this game lets you sketch lines in the<br />

air around you. You can then walk around and view<br />

your creations from different angles. The extra<br />

dimension gives you lots of new ways to interact<br />

with them – you could draw a door and walk through<br />

it, for example. You create your pictures by using<br />

the motion controller as a paintbrush and you can<br />

then share them online. The big bold strokes make<br />

players look like Jackson Pollock. Indeed, we may<br />

soon see the first VR art gallery.<br />

GOOGLE CRYTEK OWLCHEMY LABS PHOSPHOR GAMES STUDIO LLC<br />

2 April 2016 | NewScientist | 19


TECHNOLOGY<br />

ONE PER CENT<br />

Fieldnotes Factory 2050<br />

Wait,I’llreconfigure<br />

Jacob Aron crosses the frontier into the factory of the future<br />

BOND BRYAN<br />

PLANES, trains, automobiles? Not<br />

quite yet: Factory 2050 in Sheffield,<br />

UK, isn’t building anything you can buy.<br />

Instead, the brains behind the project<br />

are rethinking the manufacturing<br />

process itself, aiming to change how<br />

we make everything from airplanes to<br />

nuclear power plants.<br />

Inside the factory, things are looking<br />

a little unfinished. It opened in January,<br />

and the team from the University of<br />

Sheffield’s Advanced Manufacturing<br />

Research Centre (AMRC) are still<br />

moving in. The place is sparkling clean,<br />

and smells like a newly furnished IKEA,<br />

but it’s gearing up to change the way<br />

whole industries work by applying<br />

virtual reality, robotics and bitcoin’s<br />

blockchain.<br />

A gaggle of orange robot arms<br />

catches my eye. Built by German firm<br />

KUKA for car manufacturing, these<br />

bots are sloppy when it comes to<br />

aerospace. Making planes is so<br />

complex that they need to be<br />

assembled with 20 times more<br />

accuracy than these arms can handle.<br />

Steve Bowles, an engineer on the<br />

project, is working to fix this. Laser<br />

tracking can ensure the robots deposit<br />

an exact amount of adhesive between<br />

two parts of a wing, for instance.<br />

Too much or too little could lead to a<br />

catastrophic failure when the plane<br />

takes off.<br />

Past the orange arms is the KUKA<br />

omniMove, a robot the size of a small,<br />

squashed car. Instead of tyres, each of<br />

its eight wheels is covered in diagonal<br />

rollers that let the bot move in any<br />

direction without turning. UK<br />

construction firm Laing O’Rourke has<br />

tasked AMRC with using the<br />

omniMove to study the pouring and<br />

moving of concrete floors. The plan is<br />

for the robots to churn out modular<br />

parts for buildings and assemble them<br />

on location.<br />

AMRC foresees a future in which<br />

robots take on the drudgery of<br />

–Give me a minute, I’m tooling up–<br />

manufacturing, leaving humans to<br />

plan and formulate strategies for<br />

guiding the machines. “You can have<br />

the humans concentrating on<br />

processes that require dexterous<br />

thoughts and hands,” says Bowles.<br />

“The idea is to assist the worker.”<br />

This automated factory will<br />

generate huge volumes of data.<br />

By linking together all the cameras,<br />

lasers and other sensors the team can<br />

create a digital twin of the building<br />

“The factory will physically<br />

rearrange itself to create<br />

thebestproductionline<br />

for the job”<br />

that will monitor every manufacturing<br />

process and perhaps individual<br />

components. This will help AMRC<br />

retool on the fly, digitally swapping out<br />

parts of the production line to model<br />

changes in the hunt for efficiency.<br />

Once an automated system has<br />

determined the best set of tools,<br />

the factory can physically rearrange<br />

itself to create the best production<br />

line for the job.<br />

AMRC has also recently become<br />

interested in the blockchain, the<br />

unfalsifiable ledger technology<br />

behind the bitcoin virtual currency.<br />

It would track and certify the path<br />

of raw materials all the way to the<br />

finished product, ensuring provenance<br />

and quality. “At every interaction,<br />

you would capture data around a<br />

given material or component,”<br />

says AMRC chief technical officer<br />

Sam Turner.<br />

Factory 2050 feels like a toy shop,<br />

but the researchers aren’t just<br />

tinkering. The goal is to get the ideas<br />

straight into industrial use, rather than<br />

letting them languish in the lab. “We’re<br />

looking at how to make manufacturing<br />

processes more efficient, more safe<br />

and more reliable,” says Bowles. ■<br />

Robot ripper<br />

Last week, Apple unveiled Liam,<br />

a robot built to rip apart old phones<br />

and pull out anything that can be<br />

recycled. Made up of 29 robotic<br />

arms, Liam starts by pulling off the<br />

screen, before moving on to the<br />

guts – battery, processor and even<br />

screws. At full clip, it takes apart a<br />

phone every 11 seconds. There is<br />

currently only one Liam, in<br />

California, but Apple is building<br />

another in Europe.<br />

“So fricken excited<br />

to meet you … like<br />

humans seem so<br />

awesome”<br />

Tay greets the world (23 March).<br />

Within hours, the Microsoft chatbot<br />

had been tricked into spewing racist<br />

comments on Twitter<br />

Global face-off<br />

How many people look just like<br />

you? FaceTopo’s software could let<br />

you find out by comparing your<br />

face with thousands of others<br />

around the world. After uploading<br />

a series of selfies, an app identifies<br />

key facial features and uses them<br />

to find lookalikes from around the<br />

world, or show you how similar<br />

your face is to those of family<br />

members in previous generations.<br />

Once FaceTopo has collected<br />

enough data, its developers hope<br />

to study the degree of variation<br />

across all human faces.<br />

APPLE<br />

20 | NewScientist | 2 April 2016


Entries for $250,000<br />

Ryman Prize now open<br />

The Ryman Prize is a unique international<br />

award aimed at encouraging the best<br />

and the brightest thinkers in the world to<br />

focus on ways to improve the health of<br />

older people.<br />

The world’s ageing population means<br />

that in some parts of the globe –<br />

including most of the Western world –<br />

the population aged 75+ is set to triple<br />

in the next 30 years.<br />

In order to stimulate fresh efforts in<br />

the field, the Ryman Foundation is<br />

offering a NZ$250,000 (US$165,000)<br />

annual prize for the world’s best<br />

discovery, development, advance or<br />

achievement that enhances quality of<br />

life for older people.<br />

The inaugural Ryman Prize was won by<br />

Gabi Hollows for her pioneering work<br />

to provide affordable eye surgery for<br />

people in developing countries.<br />

The Hollows Foundation has restored<br />

sight to more than 1 million people<br />

– an amazing achievement that has<br />

transformed lives.<br />

If you have a great idea, or have<br />

achieved something remarkable like<br />

Gabi, we’d love to hear from you!<br />

Go to www.rymanprize.com for more information<br />

Gabi Hollows and Nobel Laureate Dr Erwin Neher at the presentation of the inaugural Ryman Prize<br />

www.rymanprize.com


APERTURE<br />

22 | NewScientist | 2 April 2016


Monstrous beauty<br />

HARD to believe that something so beautiful can<br />

have such a devastating effect. This is what the<br />

infamous Zika virus looks like – probably.<br />

Zika, now sweeping the Americas, was<br />

declared a global health emergency earlier this<br />

year because of the suspected link between the<br />

virus and babies born with microencephaly.<br />

Ivan Konstantinov from Visual Science and his<br />

team used their knowledge of related viruses,<br />

such as dengue, West Nile and yellow fever, to<br />

create an image of a Zika particle. “We applied<br />

the same techniques used in research and drug<br />

development to predict what it looks like,”<br />

says Konstantinov.<br />

Zika is part of the flavivirus family so its<br />

“virions” – infectious particles – are probably<br />

around 50 nanometres, less than half the size of<br />

HIV and flu. Different proteins are coloured blue,<br />

green and grey. In the top right image we can see<br />

a lipid membrane, including a protein, and in the<br />

picture below it is the virus’s RNA genome.<br />

Although the surface of the virus closely<br />

resembles dengue, says Konstantinov, it could<br />

work very differently. “It doesn’t mean that it<br />

behaves the same way in an infected organism.”<br />

Aside from microencephaly, Zika is implicated<br />

in other kinds of fetal damage, as well as in<br />

Guillain-Barré syndrome, which can cause<br />

paralysis.<br />

The team hopes to improve their model once<br />

they know how the virus’s genome organises<br />

itself inside the cell. Sandrine Ceurstemont<br />

Photographer<br />

© Visual Science, 2016<br />

2 April 2016 | NewScientist | 23


OPINION<br />

Critical moment<br />

Time for a serious rethink of the world’s biggest nuclear<br />

power project, says Paul Ekins<br />

FEW energy projects have been as<br />

racked with doubt as the nuclear<br />

power station due to be built at<br />

Hinkley Point in Somerset, UK.<br />

Fresh uncertainty followed the<br />

resignation of the chief finance<br />

director of EDF, the largely stateowned<br />

French company that<br />

would construct the plant, fearing<br />

EDF’s share of the £18 billion cost<br />

could ruin it.<br />

The backdrop is a UK<br />

government desperate for the<br />

plug not to be pulled. It cites<br />

energy security, jobs and cost of<br />

power. Nuclear plants can supply<br />

zero-carbon power continuously,<br />

and Hinkley will generate 7 per<br />

cent of current UK electricity<br />

demand for 60 years, at a rate<br />

that is now cheaper than that of<br />

power from offshore wind. Some<br />

25,000 jobs would be created.<br />

But how essential is Hinkley?<br />

That depends on electricity<br />

demand in decades to come,<br />

Bridging the gulf<br />

More US-Cuba scientific collaboration will<br />

help keep the peace, says Michael Clegg<br />

A HISTORIC visit to Cuba by<br />

Barack Obama – the first such<br />

gesture by a US president for<br />

88 years – reinforces the thaw in<br />

relations between the nations.<br />

It’s no surprise that Obama’s<br />

wish list included better scientific<br />

cooperation. He knows that this<br />

has long been a powerful means<br />

of bridge building. For instance,<br />

the US National Academy of<br />

Sciences runs workshops with<br />

scientists from Iran, and both<br />

governments seem to value this<br />

neutral channel of engagement.<br />

Similar links have been forged<br />

with China, India and Russia – and<br />

earlier with the Soviet Union.<br />

Science provides a context for<br />

dialogue when political tensions<br />

hinder other communication.<br />

What’s more, Cuba has strong<br />

capabilities in fields including<br />

biotechnology, oceanography,<br />

biodiversity, public health and<br />

disaster management. Its<br />

education system achieved nearly<br />

100 per cent literacy by the 1970s<br />

and its higher education and<br />

research sectors are impressive<br />

for a nation of just over 11 million.<br />

Obama had technology-based<br />

entrepreneurism and expanded<br />

access to the internet on his wish<br />

“One idea has suggested<br />

using the US base at<br />

Guantanamo Bay for<br />

biodiversity conservation”<br />

mainly dictated by how efficiently<br />

electricity is used and to what<br />

extent it replaces transport fuels<br />

and natural gas for heating.<br />

UK Energy Research Centre<br />

modelling suggested that demand<br />

in 2050 could be 30 per cent<br />

higher than in 2015, with greater<br />

nuclear capacity playing an<br />

important role combined with<br />

renewables and coal plus biofuels<br />

backed by carbon capture and<br />

storage (CCS). But the ground has<br />

shifted. UK CCS prospects have<br />

dimmed and the cost of electricity<br />

from renewables has fallen.<br />

By 2025, power from offshore<br />

wind is set to be cheaper than that<br />

from Hinkley. And being able to<br />

store a lot of electricity to smooth<br />

out intermittent supply from<br />

renewables is looking more likely.<br />

Lots of renewables, together<br />

with storage and a smart grid<br />

to better match generation to<br />

demand, could render obsolete<br />

list for Cuba, along with the chance<br />

to work with Cuban biotech<br />

efforts, in particular trials for<br />

new vaccines for lung cancer and<br />

other human and animal diseases.<br />

Shared environmental<br />

challenges, such as climateinduced<br />

sea level rise, preparing<br />

for hurricanes, and preserving<br />

marine resources and biodiversity<br />

suggest a cooperative approach.<br />

In this context, one visionary idea<br />

from the research community<br />

proposed using the US naval base<br />

at Guantanamo Bay as a dedicated<br />

area for biodiversity conservation<br />

(Science, doi.org/bdks).<br />

The path ahead has obstacles,<br />

not least opposition from some<br />

24 | NewScientist | 2 April 2016


For more opinion articles, visit newscientist.com/opinion<br />

the whole concept of a continuous<br />

supply of “baseload power”, which<br />

nuclear provides. Under this<br />

scenario, the mid-2020s, when<br />

Hinkley would come online, could<br />

see the UK locked into a 35-year<br />

commitment to an inflexible and<br />

expensive form of electricity illsuited<br />

to a new energy landscape.<br />

Alternatively, if Hinkley can be<br />

built without bankrupting EDF,<br />

deliver power at a predictable cost<br />

for 60 years, and if a more flexible<br />

grid proves unfeasible, then the<br />

enthusiasm may prove justified.<br />

On balance, though, the cost<br />

looks too high, and the current<br />

hiatus provides a chance to back<br />

off from Hinkley and rekindle<br />

investment in renewables, while<br />

building sufficient gas plants to<br />

act as back up in case mass storage<br />

of electricity fails to materialise.<br />

Ultimately, if EDF does pull<br />

out of Hinkley, the government<br />

will have to come back to<br />

renewables or CCS in a big way, or<br />

recognise that its carbon targets<br />

are a lost cause.<br />

The juggling act of getting<br />

secure, low-carbon power at the<br />

lowest cost is not called the energy<br />

policy “trilemma” for nothing. ■<br />

Paul Ekins is professor of resources<br />

and environmental policy at University<br />

College London, and deputy director<br />

of the UK Energy Research Centre<br />

Republicans hoping to contest<br />

the US presidential election.<br />

There are also US laws, such as<br />

an economic embargo, that still<br />

limit engagement, and changing<br />

these will require congressional<br />

action – unlikely in the short term.<br />

Despite this, collaborative<br />

research offers a valuable path<br />

to deeper ties. There are many<br />

opportunities for cooperation and<br />

each such initiative will amplify<br />

and encourage a new future<br />

between these two nations. ■<br />

Michael Clegg is co-chair of the Inter<br />

American Network of Academies of<br />

Science and emeritus professor of<br />

biology at University of California, Irvine<br />

FABRIZIO BENSCH / REUTERS<br />

INSIGHT Air pollution<br />

We need to be angrier<br />

about our toxic air<br />

Michael Le Page<br />

I WORRY about what working at New<br />

Scientist is doing to my health. Not<br />

because of the job itself, but because<br />

our office is located in one of the many<br />

parts of London where air pollution<br />

exceeds the set limits. My colleagues<br />

and I breathe in a lot more nitrogen<br />

dioxide than is good for us. And if you<br />

live or work near to a busy road, or<br />

travel on them, you probably do too.<br />

Rich countries like the UK have<br />

made a lot of progress when it comes<br />

to air pollution. We’ve gotten rid of<br />

the soot from industry that plagues<br />

countries like China and India, and<br />

more insidious threats such as lead<br />

from petrol. But we do have a big<br />

problem with nitrogen dioxide from<br />

traffic fumes. London’s Oxford Street<br />

has the highest recorded levels of<br />

nitrogen dioxide in the world.<br />

According to a European Union<br />

directive that came into force in 2010,<br />

nitrogen dioxide levels should average<br />

less than 40 micrograms per cubic<br />

metre a year and the hourly average<br />

shouldn’t exceed 200 micrograms on<br />

more than 18 occasions in a year.<br />

Parts of London sometimes breach<br />

this limit more than 18 times a week.<br />

That’s outrageous, yet there has<br />

been little outcry. ClientEarth, a group<br />

of activist lawyers, is trying to change<br />

that. It sued the UK government to<br />

force it to take action. The supreme<br />

court ruled in its favour last year.<br />

That meant the government had to<br />

come up with a new plan for reducing<br />

nitrogen dioxide. But that plan wasn’t<br />

much better than the old one: London<br />

would continue to breach the limits<br />

until at least 2025, for example. So<br />

last week ClientEarth announced it<br />

“Nitrogen dioxide is<br />

invisible. The lack of actual<br />

bodies makes it hard to<br />

mobilise public opinion”<br />

was again taking legal action to<br />

force the government to do better.<br />

The trouble is nitrogen dioxide is<br />

an invisible killer. A major report out<br />

last month concluded that air pollution<br />

causes around 40,000 deaths a year<br />

in the UK, of which nearly half are due<br />

to nitrogen dioxide.<br />

However, it isn’t possible to point<br />

to any one death and say that person<br />

was killed by nitrogen dioxide. Rather,<br />

–A big dose of nitrogen dioxide–<br />

some people are becoming ill and<br />

dying sooner than they should have<br />

done. “What we are talking about is a<br />

shortening of life,” says Ian Mudway<br />

of King’s College London. The headline<br />

figure of 40,000 deaths is a statistical<br />

way of representing this toll.<br />

The lack of actual bodies makes it<br />

hard to mobilise public opinion. And<br />

without an angry electorate, getting<br />

the government to take action is<br />

going to be an uphill struggle.<br />

Air pollution does seem to be<br />

moving up the agenda thanks to the<br />

efforts of ClientEarth and others. It<br />

has become an issue in the mayoral<br />

election for London and a recent<br />

YouGov poll on behalf of ClientEarth<br />

found that air pollution is the number<br />

one health concern for Londoners.<br />

Nitrogen dioxide pollution is an<br />

issue in many other traffic-clogged<br />

cities around the world too, but the<br />

problem is particularly bad in Europe<br />

because of efforts to reduce carbon<br />

emissions by encouraging people to<br />

buy diesel cars. Diesel vehicles emit<br />

lots of nitrogen dioxide and – as the<br />

Volkswagen scandal made clear – the<br />

systems meant to mop this up don’t<br />

work nearly as well as claimed.<br />

In the short term we need to get the<br />

most polluting vehicles off the road.<br />

And in the long term, we need to switch<br />

to hybrid or electric vehicles. If we<br />

power these with renewable energy,<br />

we can reduce carbon emissions at the<br />

same time – a win-win situation. But it<br />

won’t happen unless we demand it. ■<br />

2 April 2016 | NewScientist | 25


ASTELLAS INNOVATION DEBATE<br />

Supported by New Scientist<br />

PHOTOGRAPHY BY BEN PAGE<br />

Our Healthcare:<br />

Situation critical?<br />

Ageing populations, expanding waistlines and stricter<br />

budgets are making the future uncertain for healthcare<br />

systems. How should they prepare, ask a panel of experts<br />

at the Astellas Innovation Debate in London<br />

When Trish Greenhalgh<br />

broke a few bones in an<br />

unfortunate accident, she<br />

went to her local accident and<br />

emergency department. What she<br />

wasn’t expecting was a 6 hour wait<br />

on a hospital trolley to get the<br />

treatment she needed. As professor<br />

of primary care health sciences at<br />

the University of Oxford, she is no<br />

stranger to the trials and tribulations<br />

of the National Health Service but<br />

cites her experience as an example<br />

of a service undergoing a crisis.<br />

For her, the reasons for the delay<br />

are clear. “GPs are so stressed that<br />

they are taking time off, so patients<br />

go to accident and emergency<br />

instead,” she told an expert panel<br />

and an audience of invited guests<br />

Trish Greenhalgh says GP morale is low<br />

at the Astellas Innovation Debate<br />

2016 at the Royal Institution in<br />

London in February. “The whole<br />

system is at breaking point.”<br />

So what needs to be done? To<br />

address this question, the Astellas<br />

Innovation Debate drew together<br />

a wide range of healthcare experts<br />

to share their ideas.<br />

Norman Lamb, health<br />

spokesperson for the Liberal<br />

Democrats and a former minister<br />

of health in the UK, painted a stark<br />

picture. “I feel we are sleepwalking<br />

“While the UK spends<br />

£1 in every £12 on<br />

health, the US spends<br />

$1 in every $6”<br />

towards a crash in the healthcare<br />

system in this country,” he said in<br />

his keynote speech.<br />

But other health systems face<br />

similar challenges. “Across the<br />

developed world, costs are rising<br />

at about 4 per cent a year, and they<br />

have done throughout the postwar<br />

period,” he said.<br />

The reasons are many. For a<br />

start, we are living longer and with<br />

higher levels of chronic disease.<br />

“The number of people with three<br />

or more chronic conditions is<br />

projected to rise by 50 per cent by<br />

2019,” he said.<br />

SQUEEZED BUDGETS<br />

All this is set against a backdrop<br />

of ever tighter budgets, particularly<br />

in the UK, where the NHS is<br />

expected to have a funding deficit<br />

of £30 billion by 2020. Lamb says<br />

that only five OECD countries<br />

spend less per capita on health<br />

than the UK; all of them former<br />

Soviet bloc countries in Eastern<br />

Europe. “In terms of our spending<br />

on health, we’re way behind<br />

countries like Germany, France,<br />

the Netherlands and so on.”<br />

But simply spending more<br />

money is not the answer, says<br />

Lamb. Some healthcare systems<br />

26 | NewScientist | 2 April 2016


Clockwise from top left: the healthcare<br />

issues captured in cartoon form; guests<br />

mingle at the Royal Institution; panellists<br />

David Nicholson and Ab Klink; Katherine<br />

Murphy from the Patients Association<br />

questions the panel; the debate<br />

involved a wide range of healthcare<br />

experts; panellists Trish Greenhalgh<br />

and Martin Gaynor<br />

are more efficient than others.<br />

The world’s biggest healthcare<br />

spender is the US. While the UK<br />

spends about £1 in every £12 on<br />

health, the US spends $1 in every<br />

$6 – almost a fifth of the US<br />

economy. But Martin Gaynor,<br />

professor of economics and health<br />

policy at Carnegie Melon University<br />

in Pittsburgh, says this money isn’t<br />

always well spent.<br />

He points to the UK National<br />

Institute for Health and Care<br />

Excellence (NICE) which takes an<br />

Norman Lamb, former UK minister of<br />

health, painted a stark picture<br />

“We are sleepwalking<br />

towards a crash in the<br />

healthcare system in<br />

this country”<br />

evidence-based approach to<br />

healthcare value. “The US has no<br />

equivalent of NICE that<br />

distinguishes true value,” he says.<br />

“The UK and Europe do a much<br />

better job of that.”<br />

The Dutch healthcare system is<br />

a good example. In the 1990s, it<br />

had long waiting times that various<br />

specialists said could only be cut<br />

by throwing money at the problem.<br />

That turned out not to work, says<br />

Ab Klink, a former Dutch minister of<br />

health. There was little incentive to<br />

reduce waiting times and hospitals<br />

even found they could use long<br />

ones to attract extra government<br />

funding. So the Dutch turned to a<br />

system where health insurance is<br />

mandatory and insurers compete<br />

with one another. This immediately<br />

increased productivity and reduced<br />

waiting lists.<br />

But solving one dilemma created<br />

another. “The problem now is that<br />

cutting costs leads to specialists<br />

spending less time with patients<br />

and referring them to other<br />

specialists instead,” says Klink.<br />

The truth is that no healthcare<br />

system is perfect, says David<br />

Nicholson, who was chief executive<br />

of NHS England between 2011 and<br />

2014. He believes that the UK<br />

system has specific problems, for<br />

example in dealing with mental<br />

health issues and in managing its<br />

workforce. This last issue is likely to<br />

grow as emerging countries start to<br />

compete for UK staff.<br />

OVERSEAS THREAT<br />

Nicholson points out that India<br />

wants to recruit another 1 million<br />

doctors and China needs 3 million<br />

more. If just a tiny fraction of these<br />

come from the UK, that will have a<br />

big impact. “It’s going to really hit<br />

us,” he says.<br />

But the NHS is still able to punch<br />

above its weight, at least for now.<br />

“We can probably muddle through<br />

for another year or so,” he says.<br />

Greenhalgh is more worried. “I<br />

have been working as a doctor in<br />

the NHS for 33 years and have<br />

never seen morale so low.” But, she<br />

says, “you can’t just press a button<br />

and change the system, because of<br />

legacy”. Even if you could, there are<br />

some things that shouldn’t change.<br />

“Universal coverage is something<br />

we must maintain,” she says.<br />

Audience member Katherine<br />

Murphy agrees. As chief executive<br />

of the Patients Association, she<br />

believes patient needs are crucial<br />

but easily overlooked in the debate<br />

about the future of healthcare. “We<br />

need to ask patients what they<br />

want,” she says. But the absence<br />

of information available to<br />

patients about their treatments,<br />

possible outcomes, or the clinicians<br />

treating them, makes it hard for<br />

patients to make informed choices,<br />

she says.<br />

One potential solution is<br />

technology. Genetic tests, and the<br />

personalised treatments they allow,<br />

are widely believed to be on the<br />

verge of revolutionising healthcare.<br />

But the NHS hasn’t always been<br />

able to capitalise on new ideas<br />

quickly, says John Burn, professor<br />

of clinical genetics at Newcastle<br />

University and a founder of a<br />

company that makes gene chips.<br />

“It has been challenging to get gene<br />

chip technology into the NHS. The<br />

problem is inertia in the system.”<br />

Whatever the solution, it won’t be<br />

easy to implement. For the<br />

foreseeable future, problems like<br />

Greenhalgh’s 6-hour wait for<br />

treatment may be only the tip of<br />

the iceberg. ■<br />

2 April 2016 | NewScientist | 27


OPINION INTERVIEW<br />

Robot rescue?<br />

We’re ready to roll<br />

From lifeguards to reconnaissance drones, robots are already helping<br />

save lives. It’s time they took their place in the rescuer’s toolbox,<br />

argues Robin Murphy<br />

What motivated you to get into rescue robotics?<br />

The Oklahoma City bombing in 1995. At the<br />

time, robots were being made very small and<br />

agile, but rescue robots were golf-cart-sized<br />

devices or things developed for the nuclear<br />

industry that weighed tonnes. They could only<br />

go on top of the rubble, not into it. But there<br />

might be people trapped deep inside that you<br />

could save if you could just get to them within<br />

48 hours. Small robots, the size of a suitcase or<br />

lunch box, would clearly have been of benefit.<br />

Two decades on, what’s your approach?<br />

At the Center for Robot-Assisted Search and<br />

Rescue, our Roboticists Without Borders<br />

programme finds robot-makers willing to<br />

donate their robots and expertise to us. We<br />

essentially audition the robots, large or small,<br />

for a spot on our team. We develop potential<br />

uses for the machines we select, making them<br />

smarter and adaptable for a variety of disaster<br />

scenarios. Right now we have about 20 types of<br />

ground, air and sea robots, many at my lab in<br />

storage cases, ready for deployment when<br />

something bad happens.<br />

Have you deployed a rescue robot recently?<br />

Yes. When we heard about refugees drowning<br />

off the coast of Greece we called Tony<br />

Mulligan, CEO of a company called<br />

Hydronalix, which makes remote-controlled<br />

lifeguarding marine robots called EMILYs. He<br />

said, “I will take two experts and two EMILYs<br />

to Greece.” I met him out there in January.<br />

He donated the robots, one to the Hellenic<br />

Coast Guard and one to the Hellenic Red Cross.<br />

Why is it dangerous for refugees to land boats<br />

on Greek shores?<br />

They have bad motors and bad boats that are<br />

overloaded, and the wind conditions in that<br />

channel can suddenly change. The shores are<br />

also very rocky. If you find a good beach, great,<br />

but if you hit a bad stretch of shore, there’s no<br />

way to get off the boat or for anyone to come<br />

and rescue you from the rocks, so you are<br />

trapped. Roughly 600 people died last year.<br />

How does a marine robot help?<br />

One way is to get the refugee boats to follow<br />

an EMILY to a better shore. These robots have<br />

cameras and two-way radios to allow rescue<br />

boats to communicate with the people in peril.<br />

The robot can also deploy a flotation device if<br />

the boat goes down. Finally, if a boat gets stuck<br />

on a rocky piece of coast, EMILY can run a line<br />

out so they can clip it in tight around their<br />

boat and let one of the bigger boats pull them<br />

back out to safety – we saw that a lot. In short,<br />

we are preventing drownings.<br />

Are you working on any developments to these<br />

lifesaving robots?<br />

Yes, more automation. EMILYs are remotecontrolled,<br />

but what we would like to be able<br />

to do is have a lifeguard look at the video feed<br />

from EMILY’s onboard camera and say, “Over<br />

there, that’s the cluster of people I want you<br />

to assist”, just by circling on the screen.<br />

What other rescue situations have you<br />

attended with robots?<br />

We helped after mudslides engulfed a rural<br />

community in Oso, Washington, killing more<br />

than 40 people in 2014. In one day we went<br />

out and flew a reconnaissance drone over<br />

the mudslides to get high-resolution images<br />

from angles that crewed helicopters and<br />

satellites could not. We flew above the area for<br />

48 minutes and processed the data on a laptop<br />

PROFILE<br />

Robin Murphy is director<br />

of the Centre for Robot-<br />

Assisted Search and<br />

Rescue at Texas A&M<br />

University in College<br />

Station, where she is<br />

Raytheon professor of<br />

computer science and<br />

engineering<br />

Standing by:<br />

Murphy and an<br />

iRobot ground vehicle<br />

while we were driving back to the incident<br />

command centre. We were able to give them<br />

a high-resolution 3D representation of the<br />

entire area fast. As a result, it became obvious<br />

to the hydrologist where the river had shifted<br />

to, where the lowest points were and where<br />

was the best place to create a flood-bypass<br />

channel to prevent further catastrophe.<br />

What technological advancements with rescue<br />

robots are you most anticipating?<br />

So far everything’s been focused on what<br />

robots see, but what they feel is important to<br />

us as well, so I’m looking forward to robots<br />

with a sense of touch. It’s really hard to clean<br />

the dirt off a trapped survivor in order to start<br />

using infrared techniques to see their blood<br />

28 | NewScientist | 2 April 2016


For more opinion articles, visit newscientist.com/opinion<br />

Photographed for New Scientist by Jeff Wilson<br />

vessels and check their pulse. And if I touch<br />

them I need haptic feedback so I don’t hurt<br />

or scare the bejeezus out of them.<br />

And the newer types of mobility are exciting<br />

too, particularly snake-like robots that are able<br />

to burrow into rubble, for example. Big robots<br />

can only access big spaces, so smaller,<br />

burrowing robots are a big deal.<br />

Have your robots saved a life?<br />

No saved life has been directly attributed to<br />

one of our robots, but that would be like saying<br />

a fire truck or a search camera has saved<br />

someone’s life. They are important tools of the<br />

teams that saved lives, but at the end of the<br />

day it’s the emergency responders who do it.<br />

They are the heroes.<br />

What’s holding back the rise of the rescue bots?<br />

Right now the barriers tend to be lack of<br />

accurate knowledge about what they can do.<br />

That’s why we want them used as much as<br />

possible – seeing is believing if you want<br />

people to adopt this technology. The second<br />

thing is regulations on what government<br />

agencies can spend money on.<br />

Aren’t these machines costly?<br />

Most of our robots cost less than a fire truck;<br />

less than the fire chief’s SUV. They certainly<br />

don’t cost millions of dollars – even if you<br />

factor in training people to use them and<br />

other associated costs. The important thing<br />

is, if you reduce the physical recovery time<br />

of a disaster by just a few days you can take<br />

years off of the economic recovery time.<br />

That’s what robots allow you to do.<br />

You have said it’s unethical not to use rescue<br />

robots – why?<br />

We have now reached the point at which these<br />

technologies are proven. Not every robot is<br />

perfect and not every robot is ready, but in<br />

general these are hardened technologies that<br />

have been used in 50 disasters in 15 countries<br />

since 2001. It’s not like we suddenly came up<br />

with something out of nowhere. It was the<br />

same scenario with vaccines – at some point<br />

you just have to pony up the money and<br />

commit to it. ■<br />

Interview by Chris Baraniuk<br />

2 April 2016 | NewScientist | 29


COVER STORY<br />

SMASH<br />

AND GRAB<br />

The Milky Way’s dwarf satellites were violently<br />

acquired – and that spells trouble for established<br />

ideas of gravity, says Stuart Clark<br />

<strong>THE</strong> end of the Milky Way is already<br />

scheduled, and will be marked with<br />

fireworks. Some 4 billion years from<br />

now, the night skies will be lit by the glow of<br />

hundreds of billions of stars as the nearby<br />

Andromeda galaxy bears down on us. The<br />

two celestial giants will become one and stars,<br />

planets and gas clouds will be hurled into<br />

intergalactic space by titanic gravitational<br />

forces. Surviving stars and planets will be<br />

pitched into a jumbled cloud flaring up with<br />

new stars – floating into a long future not<br />

in the Milky Way, nor Andromeda, but a<br />

monstrous “Milkomeda” galaxy.<br />

It’s a well-established picture of our galaxy’s<br />

cataclysmic future. More controversially,<br />

it might also be a vision of its past.<br />

Observations indicate that the eviscerated<br />

remains of a past encounter between two<br />

celestial giants encircle our galaxy’s<br />

neighbourhood. Forbidden alignments of<br />

satellite galaxies, globular clusters and<br />

streams of stars trailing in our galactic wake<br />

all hint that our local cosmic history needs<br />

a rewrite. And not only that: to explain what<br />

our telescopes are telling us, we may need to<br />

rethink that most mysterious of substances,<br />

dark matter – and perhaps our entire<br />

conception of how gravity works, too.<br />

Like many big problems, this one started<br />

out small: in a strange configuration of tiny<br />

dwarf galaxies surrounding the Milky Way.<br />

In 2012, astronomer Marcel Pawlowski, then<br />

of the University of Bonn in Germany, dubbed<br />

it the “vast polar structure”. This was for the<br />

way the dwarfs line up in a ring that circles the<br />

galaxy at right angles to the main disc of stars,<br />

which contains our sun and everything else.<br />

But he was by no means the first to see it.<br />

That was Donald Lyndon-Bell of the University<br />

of Cambridge, who in 1976 pointed out that<br />

the satellite galaxies surrounding the Milky<br />

Way are not scattered randomly, but look as if<br />

something has corralled them into a distinct<br />

alignment. “They thought it could be the<br />

break-up of a larger galaxy, making it some<br />

form of debris stream,” says Pawlowski,<br />

“There was an open discussion at the time,<br />

but then the topic became unpopular.”<br />

The thing that made it unpopular was<br />

the rise of dark matter. Dark matter became<br />

30 | NewScientist | 2 April 2016


TATIANA PLAKHOVA<br />

“<strong>THE</strong> ALIGNMENT IS<br />

EXACTLYWHATYOU<br />

WOULDEXPECTIF<br />

<strong>THE</strong> TWO GALAXIES<br />

HAD INTERACTED<br />

IN <strong>THE</strong> PAST”<br />

a fixture in the 1970s to explain a glaring<br />

discrepancy between our standard<br />

cosmological models, rooted in the<br />

picture of gravity teased out by Newton and<br />

Einstein, and observations of reality. When<br />

astronomers measured the speed at which<br />

distant galaxies were rotating, they found<br />

these celestial bodies to be whirling round so<br />

fast they would fly apart if they relied only on<br />

visible matter’s gravity to hold them together.<br />

This frenzied rotation could be explained if<br />

there were more to the galaxies than met the<br />

eye – if most of their matter were not made of<br />

conventional atoms, but of particles that did<br />

not interact with light and so were invisible.<br />

Dark matter fitted ideas being floated by<br />

physicists studying the universe’s<br />

rambunctious early years, before stars and<br />

galaxies formed. In this searing environment,<br />

a panoply of new particles would have popped<br />

up to carry forces and energy. As the universe<br />

expanded and its temperature dropped,<br />

these particles would have lost their potency<br />

and become an inert, invisible soup.<br />

No one has ever detected or fabricated so<br />

much as a single particle of dark matter, yet<br />

its popularity has grown and grown. Our<br />

current standard model of cosmology has it<br />

outweighing normal matter by five to one.<br />

Existing in such quantities, dark matter<br />

not only explains galactic rotation, but also<br />

seems to be just the thing to allow galaxies<br />

such as the Milky Way to form. Tiny<br />

irregularities in the initial density of dark ><br />

2 April 2016 | NewScientist | 31


matter caused pockets of the stuff, unimpeded<br />

by interactions with anything else, to begin to<br />

collapse under their own weight. This pulled<br />

in normal matter, which collapsed down into<br />

flat, spinning discs of matter – galaxies.<br />

Simulations of this reproduce the observed<br />

form of galaxies like the Milky Way perfectly.<br />

Hot and cold spots we see in the cosmic<br />

microwave background, light sent pinging<br />

around the cosmos when it was just<br />

380,000 years old, are interpreted as<br />

indicating the seeds of this process. And so we<br />

believe that galaxies today are surrounded by<br />

a cosseting “halo” of dark matter that<br />

generates gravity and keeps everything<br />

together.<br />

Those same simulations show how, as dark<br />

matter collapses to form a galaxy halo, parts<br />

of it fragment, trapping in-falling normal<br />

matter and giving rise to a population of<br />

dwarf galaxies randomly scattered around<br />

the larger parent galaxy. So it is a bit of a<br />

problem that the Milky Way’s dwarf satellites<br />

are by no means randomly scattered.<br />

The huge success of the dark matter model<br />

meant most astronomers were content to<br />

turn a blind eye to this small embarrassment:<br />

the thought was we had simply not yet seen<br />

all the Milky Way’s accompanying dwarfs. But<br />

in 2005, Pavel Kroupa, also at the University<br />

of Bonn, reanalysed the satellite galaxy data<br />

and confirmed the striking mismatch with<br />

dark matter theory.<br />

Pawlowski, Kroupa’s doctoral student, then<br />

went further. He studied the alignment of other<br />

objects in the halo of the Milky Way – spherical<br />

collections of stars much smaller than dwarf<br />

galaxies known as globular clusters, and long<br />

wispy trails of stars thought to form when<br />

dwarf galaxies break up. He found them<br />

marshalled just like the dwarf galaxies.<br />

To explain it all, Pawlowski channelled<br />

Lyndon-Bell’s original suggestion that it<br />

could be the debris of an intergalactic collision<br />

and looked to see what the fallout of such a<br />

collision might be. He investigated whether<br />

dwarf galaxies could indeed form from the<br />

stuff left behind when two galaxies interacted.<br />

Astronomers see quite a few such galactic<br />

dances throughout the universe throwing<br />

out huge tails of stars and gas into space.<br />

Pawlowski’s simulations confirmed that the<br />

Milky Way’s dwarf galaxies could indeed form<br />

in their observed positions following such an<br />

encounter (see “When galaxies collide”, left).<br />

But what was it that danced with us?<br />

There was no obvious candidate until 2013,<br />

when Rodrigo Ibata of the Observatory of<br />

Strasbourg in France and his colleagues<br />

When galaxies collide<br />

An earlier encounter between two galaxies could be<br />

responsible for the strange ring of dwarf galaxies<br />

around the Milky Way<br />

The close encounter of two<br />

galaxies rips off huge tails of gas<br />

These tails coalesce to form dwarf galaxies<br />

in a ring at right angles to the main disc<br />

published observations that showed a similar<br />

polar structure of dwarf galaxies exists around<br />

Andromeda, our nearest galactic neighbour<br />

some 2.5 million light years away. The dwarfs<br />

above the plane of Andromeda are moving<br />

away from us, while those at the bottom are<br />

heading towards us – convincing evidence<br />

that the disc is not a chance alignment, but<br />

a coherent, rotating structure. Andromeda’s<br />

satellite disc is also rotating in the same sense<br />

as ours, and pointing at the Milky Way, albeit<br />

with a slight misalignment of about 35 degrees<br />

from our galaxy’s polar structure. It is all<br />

exactly what you would expect if the two<br />

galaxies had interacted in the past.<br />

Except they couldn’t have done. Even<br />

counting their presumed dark matter haloes,<br />

Andromeda and the Milky Way simply don’t<br />

have enough mass, and thus mutual gravity,<br />

to have pulled them into a collision in the time<br />

available since the big bang.<br />

So it’s a stalemate. Unless, that is, something<br />

is up with gravity. Newton’s and Einstein’s<br />

theories assume that gravity is a force whose<br />

strength declines with the square of the<br />

distance between two massive objects.<br />

That indeed seems to be the case on scales<br />

up to that of our solar system – the orbit<br />

of a body as far out as Pluto conforms to<br />

expectations. But it is an assumption we’ve<br />

never been able to test on larger scales.<br />

The heretical idea that gravity’s strength is<br />

not the same everywhere was proposed back<br />

in the 1980s as an alternative to dark matter.<br />

Known as MOND for “modified Newtonian<br />

dynamics”, the idea was floated by Mordechai<br />

Milgrom, then at Princeton University in<br />

New Jersey. He found that the rotation of<br />

galaxies could be almost perfectly described<br />

if, in situations where the gravitational<br />

field is comparatively weak, its strength<br />

did not continue to decline with the square<br />

of distance, but flattens out. In such<br />

environments, for example in the outer<br />

reaches of galaxies, gravity will be stronger<br />

than expected (see diagram, below right).<br />

In 2014, Hongsheng Zhao of the University<br />

of St Andrews, UK, working with Kroupa and<br />

others, showed that such a subtle change<br />

allowed for an interaction between the Milky<br />

Way and Andromeda between 7 and 11 billion<br />

years ago. “Simply speaking, MONDian<br />

dynamics demands that there was a past<br />

interaction between the two,” says Pawlowski.<br />

Superfluid epiphany<br />

But MOND is not exactly flavour of the month<br />

among physicists. Even though the strength<br />

of gravity has never been tested in very weak<br />

fields, the idea that a force of nature should<br />

change its strength so readily is unpalatable<br />

to most. And MOND runs into problems when<br />

the scales get extremely large. In clusters of<br />

many galaxies, dark matter is still needed<br />

to hold everything together. And those hot<br />

and cold spots in the cosmic microwave<br />

background are very hard to explain without<br />

some form of dark matter assisting the<br />

collapse of normal matter into galaxies.<br />

All of this gave Pawlowski pause for<br />

thought, wondering whether the MOND idea<br />

might itself be modified not just to explain<br />

a past collision between the Milky Way<br />

and Andromeda, but also to fit all other<br />

observations. “Maybe MOND is telling us<br />

something about gravity,” he says. “Or maybe<br />

it is telling us something about dark matter.”<br />

Enter Justin Khoury with the self-same<br />

question – and perhaps an answer. A<br />

theoretical physicist at the University of<br />

Pennsylvania in Philadelphia, Khoury has long<br />

been fascinated by the success of MOND in<br />

32 | NewScientist | 2 April 2016


of two models previously regarded as<br />

implacably opposed. For this hybrid model<br />

to work, his calculations suggest that the<br />

dark matter itself is a billion times lighter<br />

than current models indicate.<br />

TATIANA PLAKHOVA<br />

“ <strong>THE</strong> SUPERFLUID WOULD<br />

REPLICATE DARK MATTER ON<br />

SOME SCALES, AND MODIFY<br />

GRAVITY ON O<strong>THE</strong>RS”<br />

describing cosmic dynamics up to the scale of<br />

galaxies – and its failure with anything bigger.<br />

“You need the component that modifies gravity<br />

on galaxy scales to go quiet on cosmological<br />

scales,” he says. “How do you accommodate<br />

that?” His answer: with superfluids.<br />

Khoury’s epiphany involves a superfluid<br />

state known as a Bose-Einstein condensate,<br />

which kicks in among some types of normal<br />

matter atoms once they drop below a certain<br />

temperature. In this state, the constituent<br />

particles begin to behave as one single,<br />

coherent mass that has no viscosity and<br />

flows without impediment. When the<br />

temperature rises again, they snap back<br />

out into a normal, viscous fluid state.<br />

If dark matter particles could enter a Bose-<br />

Einstein state, Khoury reasoned, that would<br />

be just the thing to replicate MOND on certain<br />

scales, and ordinary dark matter on others.<br />

In the relatively weak gravitational fields of<br />

galaxies, dark matter would be slow-moving<br />

and have a low effective temperature. It would<br />

slip into a Bose-Einstein state whose energy<br />

would be spread uniformly across its extent,<br />

curving space and creating a MOND-like<br />

additional gravitational force. But in stronger<br />

gravitational fields, as found in galaxy<br />

clusters, the coherence would break and the<br />

matter would behave just like ordinary dark<br />

matter, contributing its own minuscule force<br />

of gravity particle by particle.<br />

This would also explain why we see no<br />

MONDian behaviour on the scale of our solar<br />

system. With our sun, we have a very strong<br />

local source of gravity, so the condensate<br />

would break down on this local level. The same<br />

would be true of each of the Milky Way’s stars,<br />

which would behave like impurities in the<br />

condensate. But because our galaxy, like all<br />

galaxies, is mainly empty space, the overall<br />

galactic condensate would still dominate.<br />

Khoury is not the first to suggest dark<br />

matter dynamics would naturally mimic<br />

those of a Bose-Einstein condensate, but he<br />

is the first to suggest it would lead to MONDlike<br />

variations in gravity, thus unifying bits<br />

Gravity assist<br />

Modified Newtonian dynamics provides a boost<br />

togravity’s strength at largedistances<br />

Strength<br />

of gravity<br />

Modified gravity<br />

Standard inversesquare<br />

gravity<br />

Distance from centre of gravity<br />

Stark mismatch<br />

Khoury is currently developing computer<br />

models to see how superfluid dark-matter<br />

haloes would affect how galaxies merge, and<br />

so see if there are any observations he could<br />

make to test the idea. He is also collaborating<br />

with a condensed-matter physicist colleague<br />

at the University of Pennsylvania, Tom<br />

Lubensky, to see if there is any supercooled<br />

atomic fluid known to create exactly the<br />

predicted effect. “If so, then perhaps we can<br />

use cold atom gases to simulate galaxies<br />

and mergers in the laboratory,” he says.<br />

Some regard talk of superfluid dark matter<br />

modifying gravity as an unnecessary and<br />

unwelcome complication – a big disruption<br />

to explain the relatively small problem of<br />

strangely aligned dwarf galaxies. Ed Shaya<br />

of the University of Maryland in College<br />

Park, for instance, thinks that the mismatch<br />

between simulations and the reality of the<br />

dwarf galaxies is down to a lack of computing<br />

power, which limits the resolution of<br />

simulations. He believes that there are still<br />

solutions invoking ordinary physics and<br />

ordinary dark matter. “It is not yet time to<br />

give up on the standard model,” he says.<br />

The distance between simulation and<br />

reality is stark for now. The vast polar<br />

structure’s ring shape is about 500,000 light<br />

years in diameter, yet no more than 50,000<br />

light years wide. Although some standard<br />

galaxy formation simulations can be rigged<br />

to produce similar alignments, they never<br />

produce rings less than a million light years<br />

in width. For Pawlowski, this mismatch is a<br />

big deal. “There are a number of problems<br />

that the standard model has on the scale of<br />

galaxies, but this is the biggest.”<br />

None of this will affect our ultimate fate,<br />

as we serenely spiral towards the giant<br />

firework show at the end of our galaxy. But<br />

will that shock and awe display be a repeat<br />

performance? Who knows – and if we have<br />

to modify our ideas of gravity and dark<br />

matter, we can’t pencil the next date into<br />

our diaries with much certainty, either.<br />

The fireworks could be going off a fair bit<br />

earlier than expected. ■<br />

Stuart Clark is a consultant for New Scientist and<br />

author of The Unknown Universe (Head of Zeus)<br />

2 April 2016 | NewScientist | 33


SERGE PICARD/AGENCE VU/CAMERAPRESS<br />

Getting the<br />

word out<br />

Often thought of as a psychological<br />

disorder, stammering could have a very<br />

different cause, finds Norman Miller<br />

IPRAY every day that no one will ask my name.<br />

That’s not because “Norman” is so terrible<br />

(it’s bad, but not that bad), but because I<br />

stammer. The thing we get asked most often<br />

in life is nearly impossible for me to get out.<br />

I’m far from alone. Also called stuttering,<br />

stammering affects around 70 million people<br />

worldwide, and every language has a word<br />

for it. Despite this, it is an enigma, often<br />

ending up the subject of humour, pity or<br />

jibes rather than serious research. And until<br />

recently, any research that did occur focused<br />

on psychological causes of a condition many<br />

linked to mental trauma or anxiety.<br />

Now, with developments in brain imaging<br />

and genetic techniques, a new picture of<br />

the condition is emerging, one that suggests<br />

a more tangible explanation. “There is<br />

something fundamentally different about<br />

the brains of people who stutter,” says Scott<br />

34 | NewScientist | 2 April 2016


Grafton, a neuroscientist at the University of<br />

California, Santa Barbara. And the hope is that<br />

a better grasp of the physiological basis of<br />

stammering could lead to better treatments.<br />

For much of history, stammerers have<br />

been subjected to often misguided “cures”.<br />

One old belief blamed abnormalities of the<br />

tongue, leading to barbaric cutting of the<br />

“offending” body part. The Greek philosopher<br />

Demosthenes worked to boost his fluency by<br />

shouting at the sea with pebbles in his mouth.<br />

In the 1920s, scientific investigation<br />

of stammering began, with a focus on<br />

psychological theories. One notable early idea<br />

was that it was caused by negative reactions<br />

by overanxious parents to children’s normal<br />

speech hesitancies – an idea still around when<br />

I was being sent to speech therapists in the<br />

1970s, despite a lack of clinical evidence.<br />

The riddles that stammering presents don’t<br />

help. Around 5 per cent of children aged 2 to<br />

5 years old will stammer at some point, but<br />

most grow out of it. And many who do stammer<br />

into adulthood can experience occasions when<br />

their speech stops stumbling – for instance,<br />

when singing or putting on a foreign accent.<br />

The fact that some people acquire a stammer<br />

as a result of brain trauma hinted there could<br />

be a neurological basis. But it was only with the<br />

advent of neuroimaging that we could finally<br />

peer at the brain in action as people stammer.<br />

Speech is produced via a series of precisely<br />

coordinated muscle movements involving<br />

breathing, phonation – or voice production –<br />

and the movement of the throat, palate,<br />

tongue and lips, known as articulation.<br />

This sequence requires sophisticated<br />

coordination of several brain areas. Brainimaging<br />

studies in people who stammer are<br />

pointing to neurological differences leading<br />

to a breakdown in this highly coordinated<br />

planning and execution process.<br />

One implicated area is the arcuate fasciculus,<br />

a bundle of nerve fibres that transmits signals<br />

to parts of the brain known to be involved in<br />

speech production. Last year, Grafton’s team<br />

scanned the brains of people who stammer<br />

and found striking differences in this area.<br />

“In the vast majority of the stutterers we<br />

scanned, there seems to be a missing branch<br />

of neural connections,” he says. This suggests<br />

that the signals involved in speech production<br />

could be getting lost. The idea is backed up by<br />

studies carried out by Kate Watkins and her<br />

colleagues at the University of Oxford, who<br />

found connectivity problems in the arcuate<br />

fasciculus of both adult and child stammerers.<br />

Other implicated regions are Broca’s<br />

area, which is involved in directing muscle<br />

movement of the mouth when you form<br />

words, and the striatum, a part of the brain<br />

located in the basal ganglia, which play a<br />

key part in facilitating voluntary movement.<br />

NIALL O’LEARY/MILLENNIUM IMAGES<br />

But studies that show stammering is related<br />

to connection faults in the speech-producing<br />

networks of the brain raise a question: why<br />

do some people overcome the condition? To<br />

find out, Christian Kell at the Brain Imaging<br />

Center in Frankfurt, Germany, has been<br />

comparing the brain function of stammerers<br />

with that of these recovered stammerers.<br />

We know that among fluent speakers,<br />

the left hemisphere of the brain takes the<br />

dominant role in speech production. In<br />

stammerers, the right hemisphere activates<br />

more strongly when speaking, even if they<br />

aren’t stammering. Kell thinks their brains are<br />

attempting to compensate for malfunctions in<br />

speech areas of the left hemisphere. “To some<br />

degree, this could reduce symptoms – but only<br />

partly, because the right hemisphere usually is<br />

not specialised in speaking,” he says.<br />

Among recovered stammerers, however, Kell<br />

found that some left-hemisphere networks<br />

TYPES OF STAMMER<br />

DEVELOPMENTAL: The most common form,<br />

appearing from childhood and probably linked to<br />

differences in brain structure (see main story)<br />

NEUROGENIC: develops as a result of<br />

strokes or other brain trauma<br />

PSYCHOGENIC: a rare form that arises after<br />

severe emotional trauma<br />

were working again – in particular Brodmann<br />

Area 47, or BA47. This is known to be involved<br />

in various speech mechanisms. In persistent<br />

stutterers, scans show BA47 as one of the areas<br />

that doesn’t activate properly, but among<br />

recovered stammerers it appears to work.<br />

So what causes these brain differences<br />

in the first place? It isn’t clear yet whether<br />

they cause the stutter or whether disfluencies<br />

in early childhood create the anomalies as<br />

the brain is developing, says Watkins. “The<br />

differences are there in young children close<br />

to the time that stammering starts, but most<br />

of the data acquired has been from adults<br />

who have stammered all their lives,” she<br />

says. The best way to solve this mystery will<br />

be studies that follow children who stammer<br />

over years or decades.<br />

Other clues come from genetics – studies<br />

using twins, for instance, show a strong<br />

genetic element. In the hunt for stammering<br />

genes, Dennis Drayna at the National<br />

Institutes of Health in Bethesda, Maryland,<br />

is focusing on families with multiple<br />

stammerers – including one extended<br />

Cameroonian family with more than 40.<br />

Finding a voice<br />

In one analysis of nearly 400 people who<br />

stammer, Drayna found three gene mutations<br />

that appeared repeatedly among them, but<br />

not in a control group. As these genes encode<br />

an enzyme that recycles cellular components,<br />

Drayna believes that these mutations could<br />

prevent the recycling of cells in brain areas<br />

related to speech processing, resulting in the<br />

sort of anomalies – such as missing neural<br />

connections – seen in scans.<br />

Even so, these types of genetic changes<br />

will only be responsible for some cases<br />

of stammering. There is now a growing<br />

understanding that stammering probably<br />

takes on different forms, each with a different<br />

cause (see “Types of stammer”, left).<br />

For those whose stammer is linked to<br />

brain changes, the discoveries are offering a<br />

glimmer of hope for the ultimate treatment –<br />

a pill to make a stammer disappear.<br />

Efforts are homing in on drugs that block<br />

the brain chemical dopamine, following the<br />

curious discovery that people given dopamine<br />

boosters to treat other conditions acquired a<br />

stutter. “Every study completed of a dopamine<br />

blocker [in stammerers] has shown positive<br />

benefit,” says neuroscientist and lifelong<br />

stammerer Gerald Maguire of the School<br />

of Medicine at the University of California,<br />

Riverside. “Dopamine medications result<br />

in a more natural speech by improving<br />

the function of the striatum. We become<br />

fluent when we sing because we bypass<br />

the defective striatum.”<br />

His money is on asenapine – a dopamine<br />

blocker that is approved to treat bipolar<br />

disorder and schizophrenia. In a small study<br />

of stammerers, Maguire found it improved<br />

fluency by between 60 and 75 per cent. Side<br />

effects were minor, so I for one am keeping<br />

my fingers firmly crossed that it makes it<br />

onto the stammering prescription list soon.<br />

Not everyone is as confident. “I think the<br />

scientific theories that implicate dopamine<br />

are persuasive,” says Watkins, “but the<br />

evidence from brain-imaging studies is not<br />

particularly clear.” Part of the problem is that<br />

studies have only been done on small groups.<br />

Still, I can take some comfort in the fact<br />

that stammering is finally getting the serious<br />

research it deserves. And that perhaps one day I<br />

will be able to say my name with confidence. ■<br />

Norman Miller is a freelance writer in Brighton, UK<br />

2 April 2016 | NewScientist | 35


36 | NewScientist | 2 April 2016


To make computers better, we need to make<br />

them worse, says Paul Marks<br />

Let’s cut them<br />

some slack<br />

KRISHNA PALEM’S computers won’t win<br />

any awards for accuracy. Most of the time<br />

they can’t even add up correctly. For<br />

them, 2 + 2 might as well be 5. But don’t be<br />

fooled by the wobbly arithmetic. Palem is<br />

making machines that could represent a new<br />

dawn for computing.<br />

Inaccuracy is not something we typically<br />

associate with computers. Since Alan Turing<br />

laid down their ground rules in the 1930s,<br />

computers have been sticklers for precision,<br />

built on the principle of following step-by-step<br />

instructions in an exact and reproducible<br />

manner. They should not make errors.<br />

But maybe we should cut them some slack.<br />

Letting computers make mistakes could be the<br />

best way to unlock the next wave of smart<br />

devices and prevent high-performance<br />

computing hitting a wall. It would allow us to<br />

run complex simulations that are beyond<br />

today’s supercomputers – models that better<br />

predict climate change, help us design more<br />

efficient cars and aircraft, and reveal the<br />

secrets of galaxy formation. They may even<br />

unlock the biggest mystery of all, by letting us<br />

simulate the human brain.<br />

Until now, we have had to accept a trade-off<br />

between performance and energy efficiency:<br />

a computer can be either fast or low-powered,<br />

but not both. This not only means that more<br />

powerful smartphones need better batteries,<br />

but also that supercomputers are energy<br />

guzzlers. Next-generation “exaflop” machines,<br />

which are capable of 10 18 operations a second,<br />

could consume as much as 100 megawatts, the<br />

output of a small power station. So the race is<br />

on to make computers do more with less.<br />

One way is simply to reduce the amount of<br />

time spent executing code – the less time<br />

taken, the less power used. For programmers,<br />

SPENCER WILSON<br />

this means looking for ways to get the desired<br />

result more quickly. Take the classic travellingsalesman<br />

problem of finding the shortest<br />

route around a group of cities. It’s notoriously<br />

tough to solve, given that the number of<br />

possible routes shoots up exponentially with<br />

the number of cities. Palem, a computer<br />

scientist at Rice University in Houston, Texas,<br />

says that coders often settle for a route that<br />

they estimate to be about half as good as the<br />

best, because to do better would use up too<br />

much computer time. A more recent version<br />

of this approach is to use a machine-learning<br />

algorithm to arrive at an approximate result for<br />

a given piece of code. This rough answer – like<br />

a back-of-the-envelope calculation – can then<br />

be used each time the program runs instead of<br />

executing the original section of code itself.<br />

But saving energy by cutting corners in<br />

software only goes so far. To really save<br />

power, you need to change the way the<br />

hardware works. Computers can save vast<br />

amounts of energy simply by not operating<br />

all their transistors at full power all the time,<br />

but as we’ll soon see, this means sacrificing<br />

accuracy. Palem’s team is hobbling computers<br />

so that they get their sums wrong in an<br />

acceptable way. “What we are proposing is to<br />

alter the computer itself to give you cheaper<br />

but slightly less accurate answers,” says Palem.<br />

Take any algorithm that you think does a good<br />

job, and he will solve it inexactly with a<br />

different physical system under the hood.<br />

Standard computer chips use a sliver of<br />

silicon called a channel to act as a switch<br />

that can flip between on (1) and off (0). The<br />

switching is controlled by a gate that stops a<br />

current flowing through the channel until you<br />

apply a voltage. Then the gate opens like a<br />

sluice in a dam, letting current through.<br />

><br />

2 April 2016 | NewScientist | 37


But it’s finicky. This complementary metaloxide<br />

semiconductor (CMOS) technology only<br />

works well when it has a reliable 5-volt power<br />

supply. Start to lower that and the channel<br />

becomes unstable – sometimes switching,<br />

sometimes not.<br />

In 2003, Palem, then at the Georgia Institute<br />

of Technology in Atlanta, saw trouble coming.<br />

It was clear that the ability of the electronics<br />

industry to continue doubling the number of<br />

transistors on a chip every 18 to 24 months – a<br />

miniaturisation trend known as Moore’s law –<br />

was coming to an end. Miniaturisation was<br />

introducing errors at the chip level. This was<br />

largely due to overheating and interference,<br />

or crosstalk, between the densely packed<br />

transistors. “It was quite likely ultra-small<br />

devices would become quite unstable,” says<br />

Palem. Power was now the critical issue.<br />

What if you could harness instabilities in<br />

some way that would also save energy?<br />

Palem’s answer was to design a probabilistic<br />

version of CMOS technology that was<br />

deliberately unstable. His team built digital<br />

MISSING BITS<br />

Krishna Palem is building an inexact<br />

computer that saves power by<br />

relaxing its precision. With this set-up,<br />

8 + 5 could equal a range of values.<br />

Here’s why: in Palem’s system,<br />

transistors representing the least<br />

significant digits in a number are<br />

deliberately run at a lower than ideal<br />

voltage. This makes them unstable,<br />

prone to flipping from 1 to 0 or 0 to 1.<br />

In a 16-bit number, the eight least<br />

significant bits could be incorrect.<br />

“As many as half the bits can be<br />

flipping,” says Palem.<br />

As a simplified example, consider<br />

adding two 4-bit numbers. In binary,<br />

8 is 1000 and 5 is 0101, and adding<br />

them should give 1101, or 13. But if<br />

the two least significant – rightmost –<br />

bits can flip, then the result<br />

could become 1100 (which is 12), 1110<br />

(14) or 1111 (15). It is possible that the<br />

inputs, 8 and 5, might get corrupted<br />

too: 1000 (8) could turn into 1001 (9),<br />

1010 (10) or 1011 (11); and 0101 (5)<br />

into 0100 (4), 0110 (6) or 0111 (7).<br />

Finally, the result of adding any two of<br />

these numbers could become<br />

corrupted as well, leading to a range<br />

of inexact answers.<br />

Modelling the crucial role of clouds in climate<br />

change is too costly with today’s computers<br />

circuits in which the most significant bits –<br />

those representing values that need to be<br />

accurate – get a regular 5-volt supply, but the<br />

least significant bits get 1 volt. “The significant<br />

bits are running at a proper, well-behaved<br />

voltage, but the least significant get really<br />

slack,” says Palem. As many as half the bits<br />

representing a number can be hobbled like this.<br />

This means that Palem’s version of an adder,<br />

a common logic circuit that simply adds two<br />

numbers, doesn’t work with the usual<br />

precision (see “Missing bits”, below). “When<br />

it adds two numbers, it gives an answer that is<br />

reasonably good but not exact,” he says. “But<br />

it is much cheaper in terms of energy use.”<br />

Spread that over billions of transistors and<br />

you have a significant power saving. The trick<br />

is to choose applications for which the least<br />

significant bits don’t matter too much: for<br />

example, using a large range of numbers<br />

to represent the colour of a pixel. In one<br />

experiment, Palem and his colleagues built<br />

a digital video decoder that interpreted the<br />

least significant bits in an imprecise way<br />

when converting pixel data into screen<br />

colours. They found that human viewers<br />

perceived very little loss in image quality.<br />

“The human eye averages a lot of things out,”<br />

says Palem. “Think about how we see illusions.<br />

The brain does a lot of work to compensate.”<br />

Encouraged by that success, the Rice<br />

University researchers have moved on to<br />

another application involving the senses:<br />

hearing aids. Their initial tests show that<br />

inexact digital processing in a hearing aid<br />

can halve power consumption while reducing<br />

intelligibility by only 5 per cent. The results<br />

suggest that we could use such techniques<br />

to slash the power used by smartphones and<br />

personal computers, given that these are<br />

basically audiovisual devices.<br />

Tim Palmer, a climate physicist at the<br />

University of Oxford, sees even greater<br />

potential. He thinks that computers based<br />

on Palem’s ideas could be the answer to what<br />

is presently an intractable problem: how to<br />

improve the accuracy of climate predictions<br />

for the next century without waiting years<br />

for a new generation of supercomputers.<br />

“The crucial question about climate change<br />

centres on the role of clouds,” says Palmer, in<br />

terms of whether they amplify or dampen<br />

the effects of global warming. “You can’t<br />

really answer that question with any great<br />

confidence unless you can simulate cloud<br />

systems directly.” And right now, it’s not<br />

NGMART/NATIONALGEOGRAPHICCREATIVE<br />

clear how to do that.<br />

Today’s supercomputers don’t have the<br />

brawn to do it, and their successors, expected<br />

in the next decade or so, will just be too<br />

energy-hungry. “Based on current estimates,<br />

the amount of power needed for such a<br />

machine is going to be around 100 megawatts,”<br />

says Palmer, five to 10 times what today’s<br />

top supercomputers use. Assuming they<br />

don’t just melt, running them could prove<br />

prohibitively costly.<br />

“Doing 20 calculations<br />

inexactly may be more<br />

useful than 10 done exactly”<br />

Supercomputers burn so much power<br />

because they are generally optimised for<br />

computing with 64-bit-long numbers. In<br />

principle, this gives greater accuracy. But<br />

climate models involve millions of variables,<br />

simulating complex interacting factors such<br />

as winds, convection, temperatures, air<br />

pressures, ocean temperatures and salinity.<br />

The result, says Palmer, is that they have too<br />

much power-draining data to crunch. What’s<br />

needed, he says, is for different variables to be<br />

38 | NewScientist | 2 April 2016


individual clouds.<br />

“Doing 20 calculations inexactly could be<br />

much more useful than 10 done exactly,” says<br />

Palmer. This is because at 100-kilometre scales,<br />

the simulation is a crude reflection of reality.<br />

The computations may be accurate, but the<br />

model is not. Cutting precision to get a finergrained<br />

model would actually give you greater<br />

accuracy overall. “It is more valuable to have<br />

an inexact answer to an exact equation than<br />

an exact answer to an inexact equation,” he<br />

says. “With the exact equation, I’m really<br />

describing the physics of clouds.”<br />

Power hungry<br />

Despite huge advances in performance, conventional<br />

computers are no match for the human brain when<br />

it comes to efficiency<br />

represented in data strings of varying length,<br />

depending on their importance to the model.<br />

Chipmakers are starting to accommodate<br />

such needs. Nvidia has launched a graphics<br />

processor unit, the TX1, that is capable of<br />

“mixed-precision” processing, allowing<br />

software to switch between 16 and 32-bit<br />

operation as it runs. But Palmer wants to see<br />

Palem’s inexact chips adopted too. “If we can<br />

reduce the number of bits that you need to do<br />

calculations, that would have an enormous<br />

impact on energy consumption,” he says.<br />

Palmer and his colleagues are talking to<br />

supercomputer makers like IBM and Cray<br />

about developing a new breed of energyefficient<br />

hybrid machines that allow varying<br />

levels of accuracy, and that may even adopt<br />

Palem’s strategy. And Palem’s team is working<br />

on mixed-precision computing with the US<br />

government’s Argonne National Laboratory in<br />

Illinois and the European Centre for Medium-<br />

Range Weather Forecasts in Reading, UK.<br />

The pay-offs could be huge. Today’s climate<br />

models tackle Earth’s atmosphere by breaking<br />

it into regions roughly 100 kilometres square<br />

and a kilometre high. Palmer thinks inexact<br />

computing would get this down to cubes a<br />

kilometre across – detailed enough to model<br />

Degrees of accuracy<br />

You can’t just give up on accuracy across the<br />

board, of course. “There is no doubt that if you<br />

represent all of the variables in the climate<br />

model with just 16 bits rather than 64 bits it<br />

would be a disaster: it would fail very quickly,”<br />

says Palmer. The challenge is choosing which<br />

parts can be treated more crudely than others.<br />

Researchers are attacking the problem<br />

from several different angles. Mostly, it comes<br />

down to devising ways to specify thresholds<br />

of accuracy in code so that programmers can<br />

say when and where errors are acceptable.<br />

The software then computes inexactly only in<br />

parts that have been designated safe.<br />

Approximation is not the answer for<br />

everyone, however. Rashid Mansoor is a<br />

London-based computer scientist and<br />

entrepreneur who invented Adbrain, an<br />

algorithm that tracks millions of web users as<br />

they move between devices. He is now looking<br />

at ways to speed up computing done in the<br />

cloud. But Mansoor sees inexactness as a last<br />

resort. “We don’t yield approximate results for<br />

the sake of speeding up computation,” he says.<br />

“We’d consider it to be cheating.”<br />

Even so, Stan Posey, who heads Nvidia’s highperformance<br />

computing team in Santa Clara,<br />

California, sees a host of applications for which<br />

inexact computing will make a big difference,<br />

including accident investigations. After the<br />

Columbia space-shuttle disaster of 2003,<br />

caused by a chunk of insulating foam breaking<br />

off and making a hole in a wing, Posey and his<br />

colleagues spent countless hours simulating<br />

scenarios that could have led to this happening.<br />

He thinks inexact computing would now allow<br />

a number of simulations an order of magnitude<br />

higher within the same time frame. Scenarios<br />

that are worth looking into more closely can<br />

then be pursued with higher accuracy.<br />

Some think inexact simulations could<br />

ultimately help us understand the brain.<br />

Supercomputers like IBM’s Blue Gene are<br />

Smartphone<br />

Desktop PC<br />

Next-generation supercomputer<br />

Human brain<br />

being used to model neurological functions in<br />

the Human Brain Project, for example. But<br />

there is a huge discrepancy in power<br />

consumption between the brain and a<br />

supercomputer, says Palmer (see “Power<br />

hungry”). “A supercomputer needs megawatts<br />

of power, yet a human brain runs on the power<br />

of a light bulb.” What could account for this?<br />

Palmer and colleagues at the University of<br />

Sussex in Brighton, UK, are exploring whether<br />

random electrical fluctuations might provide<br />

probabilistic signals in the brain. His theory is<br />

that this is what lets it do so much with so little<br />

power. Indeed, the brain could be the perfect<br />

example of inexact computing, shaped by<br />

pressure to keep energy consumption down.<br />

What’s clear is that to make computers<br />

better, we need to make them worse. Palmer is<br />

convinced that partly abandoning Turing’s<br />

concept of how a computer should work is the<br />

way forward if we are to discover the true risks<br />

we face from global warming. “It could be the<br />

difference between climate change being a<br />

relatively manageable problem and one that<br />

will be an existential problem for humanity.”<br />

And if approximate computing seems a<br />

shaky foundation on which to build the future<br />

of computing, it’s worth remembering that<br />

computers are always dealing with the<br />

abstract. “All computing is approximation,”<br />

says Posey. Some are just more approximate<br />

than others. ■<br />

Paul Marks is a technology journalist based in London<br />

2 April 2016 | NewScientist | 39


YOU<br />

SWINE!<br />

Feral pigs are wreaking<br />

havoc across the globe.<br />

But it isn’t easy to outwit<br />

these brainy beasts,<br />

says Stephen Ornes<br />

RODNEY WOODSON never set out to be a<br />

pig trapper. He joined the Tennessee<br />

Wildlife Resources Agency because he<br />

was passionate about conserving water birds.<br />

But that was before the hogs rocked up, with<br />

their high libidos and low cunning.<br />

Across the world, and especially in the<br />

southern US, feral pigs are a problem.<br />

Marauding hordes of swine are destroying<br />

crops and sensitive natural environments,<br />

causing traffic accidents and spreading<br />

disease and parasites. They have even dug up<br />

cemeteries. The US Department of Agriculture<br />

estimates the damage at $1.5 billion a year.<br />

As so often with invasive species, this is a<br />

problem of our own making. Wild pigs were<br />

introduced to the US by Spanish settlers<br />

hundreds of years ago, but weren’t a cause of<br />

widespread concern until the 1990s, says<br />

zoologist Jack Mayer at the Savannah River<br />

National Laboratory in South Carolina, when<br />

cable TV ads began promoting the animals as<br />

an exotic alternative hunting target to turkeys<br />

and deer. In 1999, Tennessee established a hog<br />

hunting season, and soon enterprising<br />

landowners were stocking up. That ushered in<br />

“an explosion of new hog populations” across<br />

the state, says Chuck Yoest, coordinator of the<br />

Tennessee Wild Hog Eradication Action Team,<br />

part of the agency that Woodson works for. In<br />

2011, the state reclassified pigs from big game<br />

to destructive pests.<br />

The pigs’ supercharged reproduction rate<br />

isn’t helping. A sow may produce two or more<br />

litters of typically five or six pigs every year,<br />

making it nearly impossible to cull all the<br />

NEW YORK STATE DEPARTMENT OF ENV/EYEVINE RODNEY WOODSON<br />

individuals in an area at once. Pig population<br />

models show that clearing an area requires<br />

removing 70 per cent of the animals “year<br />

after year after year, until you drive that<br />

population to extinction”, says Mayer.<br />

In Texas, some landowners now offer<br />

wealthy customers the opportunity to<br />

machine-gun pigs from a helicopter for as<br />

much as $1000 an hour. Other communities<br />

have called in teams of sharp shooters. But<br />

critics say that these methods of pig control<br />

are not just inhumane, but ineffective. For a<br />

start swine are fast: they can run at up to<br />

50 kilometres an hour. They can also respond<br />

to hunting pressure in surprising ways, for<br />

example switching between nocturnal and<br />

diurnal living patterns. “They’re a pain in the<br />

backside, but they are interesting critters,”<br />

says Mayer.<br />

Traps of the sort Woodson lays are generally<br />

thought to be the least bad option in dealing<br />

with the pigs. But porcine intelligence makes<br />

trapping a full time job. Pigs have been shown<br />

to beat chimps when it comes to IQ, are<br />

whizzes at navigating complex mazes and can<br />

manipulate cursors on a screen by controlling<br />

a joystick with their snout. It means in simple<br />

traps they soon work out how to jump over<br />

short fences and climb taller ones, for example<br />

by gaining purchase at a corner.<br />

Boar busting<br />

Woodson’s first tactic was to play the long<br />

game and put the pigs under surveillance. He<br />

installed cameras near baited traps, so pest<br />

control officers could examine pictures to see<br />

how many animals came by, and when. Once<br />

they knew which traps were frequented by the<br />

hogs, they could stake them out, hiding near a<br />

40 | NewScientist | 2 April 2016


Hog hordes<br />

Problem pigs are popping<br />

up across the globe<br />

UK Wild pigs went extinct in the UK<br />

300 years ago but now they are back<br />

thanks to leaky farms. Last year, a<br />

survey from the Forestry Commission<br />

estimated there were over 1000 in the<br />

Forest of Dean, on the England-Wales<br />

border, alone.<br />

Italy Last year swine in Tuscany<br />

snaffled enough Chianti grapes to<br />

fill 130,000 bottles of wine, leading<br />

wine-makers to call for mass<br />

extermination.<br />

Germany Berlin is home to thousands<br />

of wild hogs that pick through rubbish,<br />

spreading it around neighbourhoods,<br />

and sporadically attack people.<br />

Australia So-called “grunter hunters”<br />

have a huge problem on their hands:<br />

according to official estimates there<br />

are 23 million feral pigs in Australia –<br />

more than humans.<br />

trap and triggering its gate at the right moment.<br />

This was by no means a perfect strategy. It<br />

took lots of time and people, and although<br />

pigs can’t see well, they have a keen sense of<br />

smell. If they picked up the scent of a human,<br />

the pigs wouldn’t approach a trap.<br />

So in his latest iteration Woodson has<br />

gone wireless, using solar-powered cameras<br />

overlooking a circular enclosure with<br />

1.4-metre-high fences – high enough for pigs<br />

to have trouble climbing them, and with no<br />

corners to aid escape. When a motion sensor<br />

detects a pig-sized animal, it sends Woodson<br />

an email. From his own home, he can watch a<br />

real-time feed of the trap and at the right<br />

moment flip a switch to drop the gate.<br />

This human check is critical, Woodson says.<br />

If even one pig from a group is left uncaught,<br />

it may learn to avoid similar traps. Though<br />

maternal education in pigs hasn’t been<br />

studied rigorously, Woodson’s experience<br />

suggests that if it’s a sow, it may train its<br />

offspring to do the same.<br />

His creative trapping is bearing fruit: the<br />

record for one of the traps is 52 swine at once.<br />

And the wireless approach is generally<br />

becoming more popular. Landowners can buy<br />

commercial versions of remotely operated<br />

traps, including the $6000 Australian model<br />

known as the “Boar Buster”.<br />

But the story is far from over. Eager for<br />

more game, a few unscrupulous landowners<br />

are still trafficking pigs to Tennessee from<br />

neighbouring states, creating fresh pockets<br />

of infestation. Longer-term, climate change<br />

may also exacerbate things, at least in Europe.<br />

Last year, researchers at the University of<br />

Veterinary Medicine in Vienna, Austria,<br />

predicted that feral pig numbers there will<br />

surge during mild winters, as more food<br />

US A pair of pigs straying onto the<br />

runway at Florida’s Jacksonville<br />

International Airport in 1988 caused<br />

an F-16 fighter to crash and the pilot<br />

to eject. According to an Associated<br />

Press report at the time: “The pigs<br />

were killed. The pilot was bruised.<br />

The $16-million jet was destroyed.”<br />

becomes available.<br />

So others are thinking beyond traps. There<br />

is the “Judas pig” method, in which, when a<br />

group of pigs is culled, a sow is left alive and<br />

tagged with a GPS collar. She then does the<br />

hard work of finding another, doomed, tribe –<br />

at which point shooters are sent in. Then there<br />

are chemical approaches such as hog-specific<br />

poison or contraceptives. Later this month,<br />

trappers and conservationists will brainstorm<br />

new ideas in Myrtle Beach, South Carolina, at<br />

the international Wild Pig Conference.<br />

Meanwhile Woodson can’t stand idle. His<br />

latest trap has an oblong pen with two gates<br />

directly opposite each other, giving the pigs<br />

the illusion of a safe passage. The hogs in his<br />

patch are wise. It is a brutal business, and<br />

there’s no time for complacency. ■<br />

Stephen Ornes is a journalist in Nashville, Tennessee<br />

2 April 2016 | NewScientist | 41


CULTURELAB<br />

Animal crackers<br />

Pretending to be other creatures is a very human game, says Paul Cobley<br />

Being a Beast by Charles Foster,<br />

Profile Books, £14.99<br />

GoatMan: How I took a holiday from<br />

being human by Thomas Thwaites,<br />

Princeton Architectural Press,<br />

$24.95/£14.99<br />

WHO hasn’t wondered what life<br />

would be like as a (non-human)<br />

animal – flying, leaping,<br />

burrowing and doing all manner<br />

of everyday things that feral<br />

animals do? Such conjectures<br />

are universal. But who would<br />

actually go so far as to attempt to<br />

“become” a specific animal? Two<br />

new books, GoatMan and Being<br />

a Beast, offer engaging answers<br />

to this last question, even if they<br />

never quite manage to get to grips<br />

with the substance of what it is<br />

like to be another kind of creature.<br />

Both volumes veer into the<br />

territory of the classic essay by<br />

philosopher Thomas Nagel, who<br />

asked in 1974 “What is it like to be<br />

a bat?” He concluded that the core<br />

of the problem was consciousness.<br />

In the end, the consciousness of<br />

the bat would be inaccessible to<br />

us, no matter what measures we<br />

took to put ourselves in its place.<br />

“It will not help,” he writes,<br />

“to try to imagine that one has<br />

webbing on one’s arms, which<br />

enables one to fly around at dusk<br />

and dawn catching insects in<br />

one’s mouth; that one has very<br />

poor vision, and perceives the<br />

surrounding world by a system<br />

of reflected high-frequency sound<br />

signals; and that one spends the<br />

day hanging upside down by one’s<br />

feet in an attic.” Such measures<br />

would only enable one to behave<br />

as a bat seems to behave; what it<br />

is to be a bat would be another<br />

matter altogether.<br />

These books take a different<br />

view – or at least try to sidestep<br />

FELICITY MCCABE / <strong>THE</strong> GUARDIAN<br />

the problem. Recounting how,<br />

after winning a grant from the<br />

Wellcome Trust, he prepared<br />

to live like a goat, Thwaites is<br />

childishly defiant: “Well screw<br />

you, Nagel! I’m going to try<br />

anyway.” Meanwhile Foster – a<br />

traveller who sees himself in a<br />

tradition of nature writing –<br />

takes on some of the behaviours<br />

of badgers, urban foxes, otters,<br />

red deer and swifts. He takes<br />

“Beyond the entertainment<br />

afforded by the efforts<br />

of the authors, is there<br />

much to learn here?”<br />

Nagel’s suggestion for a new<br />

phenomenology to describe<br />

animal worlds as a cue for<br />

poesy or a vague reorientation<br />

of language.<br />

The projects described by each<br />

writer consist of fairly limited<br />

attempts to behave like certain<br />

animals. In terms of value for<br />

money, then, the reader can<br />

choose: at roughly the same<br />

length, one book reveals very little<br />

about one species, the other reveals<br />

very little about five species.<br />

Foster’s approach is, in some<br />

ways, allied to recent work in<br />

animal studies – a burgeoning<br />

Joining the smart sett: Charles<br />

Foster camped out as a badger<br />

field in the humanities – in the<br />

way it takes a tissue of human<br />

perspectives as its starting point<br />

and tries to transcend them.<br />

Foster camps out in a badger sett<br />

in Wales with his 8-year-old son,<br />

and prostrates himself in east<br />

London so as to gain a fox’s-eye<br />

view. Following an introductory<br />

chapter, the book is organised<br />

sequentially around highly<br />

personalised discussions of<br />

his five chosen species.<br />

Thwaites’s approach in<br />

42 | NewScientist | 2 April 2016


For more books and arts coverage, visit newscientist.com/culturelab<br />

GoatMan (out in May) is more<br />

focused. Originally wanting<br />

to live as an elephant, he takes<br />

the advice of a Scandinavian<br />

shaman and tries to “become”<br />

a goat. His chapters are devoted<br />

to “Soul”, “Mind”, “Body”, “Guts”<br />

and “Goat Life”.<br />

Despite the liberal use of irony<br />

and bathos, as well as a generally<br />

jokey tone in both books,<br />

Thwaites’s descriptions of his<br />

consultations with experts do<br />

threaten to illuminate the world<br />

of a non-human animal. In<br />

particular, his attempts – and<br />

initial failures – to replicate goat<br />

physiology are probably the most<br />

rewarding passages of either book.<br />

Blood will out<br />

Still, the reader is left<br />

wondering whether, beyond the<br />

entertainment afforded by the<br />

efforts of the authors, there is<br />

much to learn here. After the<br />

elaborate build-up in GoatMan,<br />

not to mention the enticing<br />

cover image – like the book, both<br />

comical and intriguing – it is<br />

disappointing that Thwaites<br />

seems to spend so little time<br />

among his chosen species. (He<br />

does, however, find a way to eat<br />

grass.) Foster, by contrast, has a<br />

friend bring meals to him in the<br />

badger sett.<br />

Inevitably, the reader is going to<br />

feel short-changed. It is as if both<br />

of these projects had involved<br />

the authors “becoming” me and,<br />

out of all my characteristics,<br />

had chosen drinking tea as more<br />

representative than my enduring<br />

the Northern Line, suffering<br />

athlete’s foot, carrying the<br />

consequences of an inability<br />

to afford a dental bridge, etc.<br />

Nevertheless, we can now<br />

confirm who would go so far as to<br />

try to find out what it is like to be a<br />

non-human animal – and that is<br />

the gentleman explorer, alive and<br />

kicking with his gentility intact. ■<br />

Paul Cobley is a semiotician and<br />

professor in language and media<br />

at Middlesex University, UK<br />

A drug to make us good?<br />

Jonathon Keats looks for morality in a neuroscientific mess<br />

The Myth of the Moral Brain: The<br />

limits of moral enhancement by Harris<br />

Wiseman, MIT Press, $38/£26.95<br />

IN 2007, Paul Zak<br />

gathered 68 young<br />

men to play a<br />

game. Pairing<br />

them at random,<br />

he gave $10 to one<br />

person in each<br />

pair, which the<br />

recipient was instructed to split<br />

with his partner. The former could<br />

choose how much to offer. If the<br />

latter accepted, both men kept the<br />

cash. If not, they had to return it.<br />

This is the ultimatum game, a<br />

standard economics experiment.<br />

But Zak, a neuroeconomist, gave it<br />

a twist by dosing half his subjects<br />

with oxytocin. The difference was<br />

dramatic. Those who took a dose<br />

of the hormone were 80 per cent<br />

more generous than those who<br />

didn’t. On the strength of this and<br />

In the real world, our actions and<br />

motivations have complex roots<br />

other studies linking oxytocin<br />

with trust, oxytocin has been<br />

lauded as the “moral” chemical.<br />

Harris Wiseman is sceptical.<br />

He’s also wary of morality claims<br />

for serotonin, dopamine and TMS,<br />

in which electricity is used to<br />

stimulate areas of the brain. In<br />

The Myth of the Moral Brain, he<br />

argues compellingly against<br />

“neuroprimacy” in ethics. “Moral<br />

functioning is travestied when<br />

approached primarily through<br />

biological lenses,” he writes.<br />

Through his thoughtful critique<br />

of neuroscientific reductionism,<br />

he provides a foundation for<br />

understanding the complexities<br />

of moral action.<br />

Wiseman objects to Zak’s<br />

experiments. Real life, he argues, is<br />

nothing like psychological studies,<br />

which require that participants<br />

make simple decisions in<br />

controlled conditions. To attain<br />

statistical significance, the<br />

experiments sacrifice relevance.<br />

Even more damning, Wiseman<br />

observes that the results reveal<br />

TIM O’LEARY/ MILLENNIUM IMAGES<br />

nothing about motivation. In the<br />

ultimatum game, oxytocin may<br />

make the subjects more generous,<br />

or, equally plausibly, it may make<br />

them more risk adverse – which<br />

has nothing to do with morality.<br />

As a result of these serious<br />

limitations, Wiseman thinks<br />

that neuroscience is largely<br />

counterproductive when it comes<br />

to understanding ethics. “Such<br />

studies have given us the illusion<br />

that our understanding has been<br />

deepened,” he writes, “when,<br />

arguably, the superficiality of<br />

the methods, combined with<br />

the authority the domain<br />

carries with it, have served to<br />

undermine and in fact reduce<br />

our understanding of the real-life<br />

phenomena [they] are supposed<br />

to be representing.”<br />

On one level, The Myth of the<br />

Moral Brain is a cautionary tale<br />

of overconfidence in easy fixes<br />

for deep flaws. On another level,<br />

Wiseman uses the inadequacies<br />

of neuroprimacy to stress that<br />

morality emerges not only from<br />

biology, but also from<br />

psychological, political, socialenvironmental,<br />

economic and<br />

religious influences. In such a<br />

quagmire, no drug can be<br />

expected to effectively target<br />

evil. Instead, “virtues require<br />

practice”, he writes.<br />

In this conclusion, Wiseman is<br />

convincing. The challenge is to get<br />

people to practise morally salient<br />

traits such as trust and generosity.<br />

Ironically, chemicals may help.<br />

If we believe that oxytocin<br />

makes us behave morally, we<br />

might yet be enhanced by an<br />

ethical placebo effect. ■<br />

Jonathon Keats is the author of<br />

You Belong To The Universe:<br />

Buckminster Fuller and the future<br />

2 April 2016 | NewScientist | 43


Collaboration<br />

Sara Cherry first met<br />

Carolyn Coyne when she was<br />

interviewing for her position at<br />

the University of Pennsylvania,<br />

where Coyne was a postdoc.<br />

What began as a casual<br />

collaboration quickly grew<br />

into something more. When<br />

Coyne moved to take a job<br />

at the University of Pittsburgh<br />

and found her laboratory<br />

wasn’t ready, Cherry offered<br />

her space in her lab and in her<br />

home. They worked together to<br />

identify host genes that can help<br />

viruses like those that cause<br />

meningitis cross the blood-brain<br />

barrier. The collaboration was<br />

hugely successful, resulting in a<br />

publication in a top tier journal and<br />

a strong friendship that lasts to this<br />

day.<br />

The two infectious disease<br />

researchers have talked regularly<br />

over the last ten years, as much<br />

about their husbands and kids as<br />

about their science. But then the<br />

Zika virus began to spread across the<br />

Americas, leaving devastating birth<br />

defects in its wake, and the phone<br />

calls became a daily occurrence.<br />

3 Tips on<br />

How to Have a<br />

Successful Collaboration<br />

1. Be open and honest. There is no<br />

such thing as a perfect collaboration<br />

(or relationship), says Coyne, but<br />

open and direct communication is<br />

absolutely necessary to establish<br />

the mutual trust needed for a<br />

successful partnership.<br />

2. Take the long view. When you are<br />

¿UVWVWDUWLQJ\RXUODELWLVHDV\<br />

to focus on authorship or other<br />

accolades. Recognize that if you<br />

behave respectably and share credit<br />

appropriately, then everyone will<br />

EHQH¿W<br />

3. Have fun. It is important to like<br />

and want to spend time with<br />

your collaborators, Cherry says,<br />

otherwise the work is no fun. The<br />

same characteristics that make a<br />

good friend can also make a good<br />

collaborator.<br />

specialized cells that reside in the<br />

blood-brain barrier and the placenta<br />

that can protect from infection. Cherry<br />

has expertise in screening strategies<br />

to identify new genes and pathways<br />

in viral replication. Together, they are<br />

searching for FDA-approved compounds<br />

that can block Zika infection in placental<br />

cells. The duo already found a handful<br />

of promising candidates, which will<br />

need to survive several more rounds of<br />

rigorous testing before they could ever<br />

be used in the clinic. Cherry says that<br />

such collaborations can only succeed<br />

when people share mutual trust and<br />

respect for each other, and each play<br />

their part.<br />

“We can’t all be an expert at<br />

everything,” said Cherry. “There are<br />

very few labs and few people who<br />

can do everything well and want to<br />

do all these different things well. We<br />

all have our own personal interests<br />

and excitement. As the world gets<br />

more and more sophisticated,<br />

the assays, the technology, the<br />

biology, I think it benefits us to<br />

take advantage of expertise more<br />

broadly.”<br />

“It was pretty clear that we should work<br />

together to understand and combat this<br />

virus,” said Cherry. “We keep each other<br />

informed about all the experiments we<br />

have going on in the lab, and that way<br />

we can share any assays or tricks that<br />

we find. It is helpful to have that kind of<br />

relationship. We are friends, and we know<br />

that we wouldn’t do anything to compete<br />

with each other. We know exactly what<br />

each we can contribute, because we have<br />

overlapping but different skill sets.”<br />

Coyne has expertise in barrier cells, the<br />

To read the complete article provided to New Scientist by Burroughs Wellcome Fund visit:<br />

http://www.bwfund.org/grant-programs/career-guidance


Incorporating ScienceJobs.com<br />

To apply online visit newscientistjobs.com<br />

East Coast Office, 50 Hampshire Street, Cambridge, MA 02142<br />

Email NSSales@NewScientist.com Phone 781 734 8770<br />

Calls may be monitored or recorded for staff training purposes<br />

MS in Bioinformatics<br />

at Boston University<br />

A post-doctoral position is available in the Said Lab at Department of Cancer Biology,<br />

Wake Forest University School of Medicine. Our laboratory is involved in translational<br />

UHVHDUFK WR VWXG\ WXPRU PLFURHQYLURQPHQW LQÀXHQFHV RQ FDQFHU LQLWLDWLRQ SURJUHVVLRQ<br />

and metastasis. We seek individuals with a strong background in cell and molecular<br />

biology, and a strong understanding of cancer biology. We use functional proteomics,<br />

genomics and metabolomics approaches to identify novel and key regulators of tumor<br />

JURZWK DQG PHWDVWDVLV DQG WUDQVODWH RXU ¿QGLQJV LQWR WKHUDSHXWLFV 7KH VXFFHVVIXO<br />

candidate will be highly motivated and organized, who think independently but enjoy<br />

working as part of a dynamic, collaborative and multidisciplinary team. Excellent verbal<br />

and written communication skills are essential.<br />

Successful applicants will have:<br />

• A recent PhD and/or MD degree (0 - 3 years of Post-Doctoral experience is preferred).<br />

• Experience working with murine models, and mouse genetics<br />

• Background in cell biology, biochemistry and molecular biology skills<br />

• Biostatistics and bioinformatics background preferred<br />

$WOHDVW ¿UVW DXWKRU SXEOLFDWLRQ<br />

Applications for this position should include CV, name and contact information of three<br />

references, and should be sent to Dr. Neveen Said (nsaid@wakehealth.edu).<br />

One of the first programs of its kind,<br />

the Bioinformatics Graduate Program<br />

offers unique interdisciplinary training<br />

in the science, engineering, medicine<br />

and ethics of twenty-first century cell<br />

biology.<br />

Now awarding MS Merit Scholarships,<br />

providing tuition assistance to full-time<br />

students on a competitive basis<br />

The Master’s degree requires a total of 32<br />

credits.Completetheprograminjustone<br />

year or enroll part-time for a schedule<br />

that fits your lifestyle. BU Bioinformatics<br />

offers an MS degree in Bioinformatics,<br />

or an MS in Bioinformatics with a focus<br />

on Translational Medicine<br />

Application Deadlines:<br />

July1forfall|December15forspring<br />

bu.edu/bioinformatics/<br />

2S@QSAXƥMCHMFXNTQODQEDBSQNKD<br />

6HSGGTMCQDCRLNQDINARONRSDC@SNew Scientist Jobs,<br />

SGDQDŗRMDUDQADDM@ADSSDQSHLDSNƥMC@MDWBHSHMFMDVQNKD<br />

Visit jobs.newscientist.com<br />

and start your search today!<br />

2 April 2016 | NewScientist | 45


www.NewScientistJobs.com<br />

Faculty Position<br />

Department of Bioinformatics and Genomics<br />

College of Computing and Informatics<br />

University of North Carolina at Charlotte<br />

SUMMER PREVIEW<br />

June 23-24, 2016<br />

Ann Arbor, Michigan<br />

Apply online: March 1 - April 12, 2016<br />

medicine.umich.edu/postdoc<br />

The University of Michigan Medical School<br />

Postdoc Preview will introduce graduate<br />

students in the biomedical sciences to the<br />

extensive research and training opportunities<br />

at Michigan. During a fully-funded visit,<br />

recruits will interview with prospective<br />

mentors and network with current postdocs.<br />

Eligibility:<br />

Applicants must be U.S. citizens, permanent<br />

residents or currently enrolled in a U.S.<br />

graduate institution.<br />

Bioinformatics<br />

Biological Chemistry<br />

Biophysics<br />

Cancer Biology<br />

Cell Biology<br />

Computational Biology<br />

Developmental Biology<br />

Research Areas:<br />

Human Genetics<br />

Immunology<br />

Microbiology<br />

Molecular Pathology<br />

Molecular Physiology<br />

Neuroscience<br />

Pharmacology<br />

The University of North Carolina at Charlotte invites applications for faculty<br />

at the Assistant or Associate level in the Department of Bioinformatics and<br />

Genomics in the College of Computing and Informatics. The Department<br />

seeks candidates with a proven research record in Computational Systems<br />

Biology, directed toward the theoretical modeling and simulation of complex<br />

biological systems, alone or in combination with experimental approaches.<br />

The successful candidate should have an earned doctorate and be eligible<br />

for appointment at the rank of Assistant or Associate professor. We seek<br />

applicants with a commitment to excellence in graduate and undergraduate<br />

teaching and mentorship who have exceptional computational/analytic skills to<br />

meet teaching requirements in one or more of the following areas: Statistics,<br />

Programming, Structural Biology, Big Data Analytics as applied to biological<br />

datasets, Machine Learning, and Integrative Systems Biology.<br />

Research areas of interest include the development and application of data<br />

analytic and theoretical methods, mathematical modeling, and simulation<br />

techniques. Research should address important biological data analysis needs<br />

such as structural and functional modeling of biomolecules and molecular<br />

interactions, or integration of heterogeneous data sets into models of complex<br />

systems, to address issues of health, agricultural productivity, and the<br />

environment.<br />

We offer a collegial environment, excellent facilities, a competitive start-up<br />

package, and a competitive nine-month salary commensurate with experience.<br />

Applications must be made electronically at https://jobs.uncc.edu (position<br />

#1732) and must include a CV, contact information for 4 references, and<br />

statements on research and teaching. Preliminary inquiries may be addressed<br />

to Dr. Cynthia Gibas (cgibas@uncc.edu). The University of North Carolina at<br />

Charlotte is an EOE/AA employer and an NSF ADVANCE Institution.<br />

For additional information, please visit our website at<br />

http://bioinformatics.uncc.edu.<br />

Faculty Position<br />

Computational Genomics<br />

Department of Bioinformatics and Genomics<br />

College of Computing and Informatics<br />

University of North Carolina at Charlotte<br />

The Department of Bioinformatics and Genomics at the University of North<br />

Carolina at Charlotte seeks a tenure-track professor at any career stage<br />

to work at our location in the North Carolina Research Campus (NCRC) in<br />

Kannapolis. The NCRC is a public-private partnership between corporations,<br />

universities and healthcare organizations advancing science at the<br />

intersection of human health, nutrition and agriculture.<br />

The NCRC hosts,UNC Charlotte, six other UNC system universities as well<br />

as Duke University. UNC Charlotte has a leadership position at the NCRC in<br />

bioinformatics. We seek applicants wishing to develop a research program in<br />

bioinformatics, computational biology and/or computational genomics. This<br />

position is part of a larger university-wide research initiative in Data Science<br />

and Analytics. The successful applicant will have an earned doctorate with<br />

an exceptional record of achievement and will be expected to maintain<br />

an externally funded research program that will catalyze a larger group<br />

of interdisciplinary scientists. The responsibilities of the position include<br />

teaching quantitative skills such as programming and statistical modeling at<br />

the graduate and undergraduate level.<br />

We offer a collegial environment, excellent facilities, a competitive start<br />

up package, and a competitive nine-month salary commensurate with<br />

experience.<br />

Preliminary inquiries about the position can be made to Dan Janies via<br />

email djanies@uncc.edu. However, formal applications must be made<br />

electronically at https://jobs.uncc.edu (position #1074) and must include<br />

a CV, contact information for 4 references, and statements on research<br />

and teaching. The University of North Carolina at Charlotte is an EOE/AA<br />

employer and an NSF ADVANCE institution.<br />

For additional information, please visit our websites at<br />

http://bioinformatics.uncc.edu and http://transforming-science.com.<br />

48 | NewScientist | 2 April 2016


Cancer<br />

Research Jobs<br />

With hundreds more jobs posted on New Scientist Jobs,<br />

there’s never been a better time to find an exciting<br />

new role!<br />

Search the latest Cancer & Oncology jobs at<br />

jobs.newscientist.com<br />

Facebook/NewScientistJobs<br />

Twitter @Science_Jobs


www.NewScientistJobs.com<br />

Professional Development Tools to<br />

Empower you and Skyrocket your Career<br />

Elsevier’s books are available online via ScienceDirect, eBook, or in print format!<br />

Visit store.elsevier.com/professional-development for more information!<br />

IN SEARCH OF<br />

REMARKABLE SCIENTISTS<br />

Molecular Technologist, Houston, Texas<br />

Do you have a PhD in microbiology or biochemistry with a<br />

strong desire to change the world to biofuels? Then we’d like<br />

you to help us pilot an exciting new project.<br />

Joining our in-house microbial biofuels team, you’ll be<br />

working with transformable host organisms to efficiently<br />

produce different biofuel components at both lab and pilot<br />

scale. You’ll need experience in one or more of the following<br />

areas: metabolic pathway improvement via transformation,<br />

microbial/pathway evolution, transformation of non-standard<br />

hosts, solid or liquid fermentation (batch or continuous flow<br />

at pilot scale).<br />

Find out more and apply online at www.shell.com/careers.<br />

In the “Students and Graduates” section, click on “Shell<br />

Recruitment Day” and then create an account. When entering<br />

your contact details, select “Other” in response to “Where<br />

you found out about this Shell opportunity,” click “Next” and<br />

then type in “Biofuels.”<br />

DISCOVER WHAT YOU CAN ACHIEVE AT SHELL<br />

Head of Research, Belfer Center<br />

for Applied Cancer Science<br />

The Belfer Center for Applied Cancer Science at the<br />

Dana-Farber Cancer Institute is seeking a highly motivated<br />

individual for Head of Research. The successful candidate will<br />

provide leadership, scientific and translational research vision<br />

and expertise, and lead a group of over 40 research scientists<br />

and associates. The Belfer Center is dedicated to improving<br />

drug development in oncology through collaborative efforts<br />

with both industrial partners and academic investigators.<br />

A major focus of the Belfer Center is on translational research<br />

studies including target validation, tumor profiling, the<br />

generation and evaluation of patient derived xenografts, and on<br />

studies of cell free DNA. Position requires a Ph.D. and/or M.D.<br />

with an outstanding record (10+ years) of academic and/or<br />

industry achievements in cancer biology, translational research<br />

and drug development.<br />

Forconsideration,pleasesubmityourCVandcoverletterto<br />

our career site (Job ID #27726).<br />

Dana-Farber.org/Careers<br />

Minority, Female, Disabled and Veteran EEO/AA Employer.<br />

Dana-Farber Cancer Institute is an Affirmative<br />

Action/Equal Opportunity Employer.<br />

50 | NewScientist | 2 April 2016


www.NewScientistJobs.com<br />

2 April 2016 | NewScientist | 51


LETTERS<br />

letters@newscientist.com @newscientist newscientist<br />

EDITOR’S PICK<br />

Theory proposes,<br />

the world disposes<br />

From Michael Duff<br />

I take issue with the critique of the<br />

role of experiment in theoretical<br />

physics by Jim Baggott and Daniel<br />

Cossins (27 February, p 38). May<br />

a physicist be allowed to set the<br />

record straight? The concept of<br />

supersymmetry was not<br />

“conceived as an elegant way to<br />

plug holes in the standard model”<br />

of particle physics. It was first<br />

noted by string theorists and then<br />

applied to supergravity. Had Albert<br />

Einstein not discovered relativity,<br />

then supersymmetry would force<br />

us to invent it.<br />

Most string theorists share<br />

the view that in the long term<br />

the test of a good theory is<br />

experiment. The jury is still out<br />

on the multiverse, for example.<br />

It is those who claim already<br />

to know whether or not our<br />

universe is unique who are being<br />

unscientific – as are those who<br />

claim to know what can and can’t<br />

one day be tested.<br />

Baggott and Cossins write that<br />

“theoretical physicists have grown<br />

increasingly comfortable plucking<br />

theories out of thin air… The Higgs<br />

boson is a case in point.” But the<br />

Higgs was proposed in 1964 and<br />

discovered in 2012, in one of<br />

theory’s greatest triumphs. And<br />

let’s not forget gravitational<br />

waves, first proposed in 1916,<br />

whose discovery 100 years later<br />

confirmed the existence of black<br />

holes – which were proposed by<br />

John Michell in 1783.<br />

London, UK<br />

Social intelligence<br />

all the way down<br />

From Duncan Butlin<br />

Aviva Rutkin focuses on the<br />

wrong sort of human behaviour<br />

when comparing human and<br />

artificial intelligence (19 March,<br />

p 20). The human brain is not<br />

designed to be good at chess,<br />

Jeopardy or Go.<br />

Even object manipulation is not<br />

one of our fortes. It is the things<br />

we do socially that a machine will<br />

find very hard to match. Making<br />

sure granny is offered the last<br />

cucumber sandwich at a tea party,<br />

or ceasing to discipline a child<br />

when you sense you may go too<br />

far, for example. When machines<br />

can model human behaviour<br />

in groups, in all its recursive<br />

splendour, only then will we have<br />

a real challenge on our hands.<br />

Chichester, West Sussex, UK<br />

Ingredient-free<br />

marketing works<br />

From Richard Nissen<br />

Shannon Fischer’s description<br />

of the power of placebos is<br />

fascinating (12 March, p 32). It<br />

chimes with my having heard<br />

the marketing manager for a bigbrand<br />

painkiller saying that the<br />

more you advertise the stronger<br />

the drug becomes – and that its<br />

effects kick in within 5 minutes,<br />

which is pharmacologically<br />

impossible.<br />

London, UK<br />

How would loyalty<br />

cancel a stench?<br />

From Garry Trethewey<br />

You report a finding that body<br />

odour produces less disgust<br />

when attributed to a member<br />

of the smeller’s group, and<br />

Stephen Reicher’s comment that<br />

because loyalties can affect a core<br />

biological response that shows<br />

how powerful and malleable<br />

group identities can be<br />

(27 February, p 20). I find it more<br />

interesting that a “core biological<br />

response” can be affected by<br />

psychosocial events. I wonder<br />

whether this is a basis for the<br />

placebo effect.<br />

Cherryville, South Australia<br />

Is doping partly<br />

mind over matter?<br />

From Alastair Monro<br />

In recurrent furores over doping<br />

in sports, I have not noticed any<br />

consideration of the role of the<br />

brain in performance as outlined<br />

in James Witts’s informative<br />

article (30 January, p 38). Could<br />

any improved performance of<br />

an athlete on a performanceenhancing<br />

drug not be due, at<br />

least in part, to a mental change?<br />

Having worked on many<br />

clinical trials, I propose one for<br />

athletes in which half of the test<br />

group is on the real drug and half<br />

on a placebo, no one knowing<br />

which. Sadly, I find it difficult to<br />

imagine top athletes agreeing to<br />

participate in such a study.<br />

Sandwich, Kent, UK<br />

A bump passing in<br />

the quantum night<br />

From Alan Wilson<br />

I am as excited as anyone about<br />

the possibility of a new particle<br />

being discovered that would<br />

shake up our understanding of<br />

the universe (5 March, p 30). But<br />

I am a little alarmed that it turns<br />

up at exactly six times the mass<br />

of the Higgs boson.<br />

To me it seems more likely<br />

that it is an artefact of statistical<br />

analysis, and might turn out to be,<br />

to put it in musical instrument<br />

terms, a harmonic of the Higgs.<br />

I fear that it will just fade away<br />

like the Cheshire Cat, leaving<br />

nothing behind but an enigmatic,<br />

vanishing smile. Of course, the<br />

idea of a harmonic might just<br />

be plausible if we visualise it in<br />

terms of string theory.<br />

Colmworth, Bedfordshire, UK<br />

Fusion reactors<br />

are all difficult<br />

From Alessandro Tesini<br />

David Hambling mentions a new<br />

breed of leaner, meaner nuclear<br />

fusion reactor, including the<br />

“affordable, robust, compact”<br />

ARC device (30 January, p 34). But<br />

the claims for ARC include rapid<br />

dismantling and re-assembly of<br />

the lining and the shell of the<br />

“doughnut” in which fusion takes<br />

place. These need to be replaced<br />

as the flux of neutrons from the<br />

reaction makes them radioactive<br />

and thus weakens them.<br />

I can report from experience<br />

that this replacement will require<br />

a very big “hot cell” containing<br />

complex equipment for remote<br />

handling of the radioactive parts.<br />

The ARC designers propose<br />

including a tank of molten<br />

fluorine-lithium-beryllium salt<br />

(FLiBe) in the shell. This will<br />

involve solving the problem of<br />

welding replacement segments of<br />

the tank to irradiated metal in the<br />

adjacent segments. And there are<br />

issues of toxicity and long-lasting<br />

radioactive contamination of the<br />

FLiBe. ARC’s claimed “plug-andplay”<br />

flexible configuration is<br />

only theoretical: the more<br />

radioactive it becomes, the more<br />

difficult it will be to reconfigure<br />

it to the extent claimed.<br />

Luynes, France<br />

How to detect an<br />

absent neutrino<br />

From Dieter Gold<br />

Matthew Chalmers describes the<br />

neutronless double beta decay<br />

and the difficulty of detecting it<br />

(13 February, p 30). It is already<br />

very difficult to detect the<br />

presence of a neutrino.<br />

52 | NewScientist | 2 April 2016


“Until the poachers come through and kill<br />

them. Will they have some sort of protection?”<br />

Sara Mains Palkovich is sceptical about plans to<br />

reintroduce extinct species to Europe (26 March, p 8)<br />

So how can we be sure we<br />

have detected the absence of a<br />

neutrino? How can researchers<br />

be sure that they have observed<br />

a double beta decay without a<br />

neutrino, instead of one with two<br />

of them? Can there be sufficiently<br />

precise measurement of the<br />

momentum of the detected<br />

particles to be sure that no<br />

momentum is carried away by<br />

the neutrinos of an ordinary<br />

double beta decay?<br />

Voiron, France<br />

From Lindsay Coker<br />

An intriguing cover line: “Once in<br />

100 trillion trillion years – we’re<br />

about to see the rarest event in the<br />

universe” (13 February), though<br />

the article (p 30) says it may<br />

happen every 10 25 years.<br />

Mornington, Victoria, Australia<br />

The editor writes:<br />

■ Neutrinoless double beta decay<br />

(NDBD) does emit electrons,<br />

whose energies and directions<br />

of motion can be measured<br />

accurately enough to discriminate<br />

it from other decays. And the<br />

article reported the lower limit<br />

on NDBD half-life, established as<br />

TOM GAULD<br />

10 25 years, though the full range<br />

now being investigated stretches<br />

up to 10 27 years.<br />

Nudge theory and<br />

regulation practice<br />

From Hugh Robertson,<br />

Senior Policy Officer, Trades<br />

Union Congress<br />

Your leader “A nudge too far?”<br />

makes some interesting points<br />

but perpetuates the idea that<br />

the work of the UK Behavioural<br />

Insights Team uses a solely<br />

“evidence-based” approach<br />

(12 March, p 5). As you rightly<br />

point out, nudges are seen as a<br />

replacement for legislation. It<br />

would therefore be appropriate<br />

to compare the outcome of a<br />

“nudge” with the likely outcome<br />

of regulation.<br />

That is not what the trials<br />

do. The biggest nudge in the<br />

UK was the Responsibility Deal<br />

which attempted a voluntary<br />

approach to health issues around<br />

food, alcohol and the workplace<br />

by getting pledges from<br />

manufacturers, retailers and<br />

employers. These were viewed<br />

by most public health experts<br />

as totally ineffective. Instead,<br />

there have been calls for the<br />

government to introduce<br />

regulation such as compulsory<br />

labelling and minimum<br />

alcohol pricing. The deals have<br />

all now been abandoned by the<br />

government and a sugar tax has<br />

been announced.<br />

Nudge theory has its place, but<br />

to state that it is evidence-based<br />

is a stretch when, in the UK, its<br />

application is underpinned by<br />

an ideological assumption that<br />

regulation is inherently negative.<br />

The evidence is that regulation<br />

can be far more effective than<br />

behavioural interventions, as<br />

shown by a range of public safety<br />

and health laws, from seat-belt<br />

use to workplace smoking.<br />

London, UK<br />

Shocking timing<br />

in obedience trial<br />

From Chris Wilkinson<br />

Andy Coghlan reports a modified<br />

version of the infamous Milgram<br />

experiment on obeying orders, in<br />

which participants were asked to<br />

estimate the time lapse between<br />

pressing a key and hearing a tone,<br />

in milliseconds (27 February, p 14).<br />

My estimate is that the best that<br />

I could do would be to report to<br />

the nearest 250 milliseconds. Did<br />

some reported estimates really<br />

go to three significant digits?<br />

Turramurra, New South Wales,<br />

Australia<br />

The editor writes:<br />

■ The experiment built on earlier<br />

work showing that the perceived<br />

time delay (not necessarily the<br />

actual delay) correlates with a<br />

sense of agency or control.<br />

Participants were indeed asked to<br />

make use of all possible numbers<br />

between 0 and 1000 milliseconds.<br />

For the record<br />

■ This one is far away: it was Mike<br />

Brown of the California Institute of<br />

Technology who observed that, seen<br />

from the Oort cloud, the sun appears<br />

so small that you could completely<br />

block it out with the head of a pin<br />

(19 March, p 30).<br />

■ Delila Gasi-Tandefelt and her<br />

colleagues are taking blood samples<br />

from men with advanced prostate<br />

cancer in sequence, not at fixed<br />

intervals (19 March, p 38). And Bert<br />

Vogelstein and colleagues make<br />

strands of DNA that mirror their<br />

target mutation, and tag these with<br />

a fluorescent marker so that they can<br />

detect any bits of mutated DNA that<br />

stick to their bait.<br />

■ A bass-ic mistake: the song of<br />

lonely Whale 52 has recently<br />

deepened from 52 Hz to 47 Hz<br />

(19 March, p 30).<br />

Letters should be sent to:<br />

Letters to the Editor, New Scientist,<br />

110 High Holborn, London WC1V 6EU<br />

Email: letters@newscientist.com<br />

Include your full postal address and telephone<br />

number, and a reference (issue, page number, title)<br />

to articles. We reserve the right to edit letters.<br />

Reed Business Information reserves the right to<br />

use any submissions sent to the letters column of<br />

New Scientist magazine, in any other format.<br />

2 April 2016 | NewScientist | 53


We are<br />

recruiting<br />

600 of the<br />

world’s best<br />

research<br />

minds to join<br />

us in Sydney<br />

unsw.edu.au/apply


UNSW Australia is a world top 50 university* with<br />

55,000 students from over 120 countries.<br />

A global recruitment drive for the world’s best research minds is<br />

being launched with unprecedented investment made to recruit<br />

up to 130 new world-leading researchers and rising stars as well<br />

as 500 new PhD scholars.<br />

UNSW is finding innovative solutions to some of the world’s grand<br />

challenges including climate change, human migration, energy<br />

and population ageing. Our University is committed to addressing<br />

these global issues drawing from the areas of Art & Design, Arts<br />

& Social Sciences, Built Environment, Business, Engineering, Law,<br />

Medicine and Science.<br />

Help us make a difference to people’s lives at<br />

Australia’s Global University.<br />

unsw.edu.au/apply<br />

* 2015 QS World University Rankings


FEEDBACK<br />

For more feedback, visit newscientist.com/feedback<br />

PAUL MCDEVITT<br />

WHEN is a drug not a drug? The<br />

UK government’s Psychoactive<br />

Substances bill seeks to prohibit the<br />

sale of consumables that affect a<br />

person’s mental state. Previously,<br />

the minister in charge of the bill, Mike<br />

Penning, insisted “We will ensure that<br />

we insert what we want to insert,<br />

while at the same time having a<br />

blanket ban” (14 November, 2015).<br />

Now we learn what he meant as,<br />

in addition to the government’s own<br />

lengthy list of exempted inebriants<br />

such as alcohol and nicotine, the<br />

Advisory Council on the Misuse of<br />

Drugs (ACMD) has been tasked with<br />

finding a way to exclude alkyl nitrites.<br />

Otherwise known as poppers,<br />

this recreational drug is a popular<br />

sex aid because of its muscle-relaxing<br />

effects, as well as its instant high.<br />

Following an investigation, the ACMD<br />

reported that although poppers<br />

increase blood flow to the brain, they<br />

don’t cross the blood-brain barrier.<br />

The ACMD concludes that any<br />

psychoactivity is a peripheral effect,<br />

and poppers do not directly stimulate<br />

the central nervous system – even<br />

though users feel a high. The circle<br />

deftly squared, another popular drug<br />

falls outside the UK’s increasingly<br />

threadbare blanket ban on drugs.<br />

FUR<strong>THE</strong>R to observations on the<br />

quantum superposition of USB<br />

cables (5 March), Sue McDonald<br />

comes unstuck over another case<br />

of strange geometries.<br />

“I was trying to find the end<br />

of the sticky tape on its roll,” she<br />

writes. “Assuming the roll is a<br />

circle with an infinite number of<br />

sides, I’ve experienced infinity + 1,<br />

which is the number of sides of<br />

the sticky tape roll I have to<br />

investigate before finding the<br />

end of the tape.”<br />

Feedback thinks this is a serious<br />

underestimate – we have to rotate<br />

a roll of sticky tape through at<br />

least 720 degrees before finding<br />

the end.<br />

SWISS army equipper Victorinox<br />

have been pricked by criticism after<br />

a customer noticed the online store<br />

had 51 “neutral” pocket knives and<br />

“Daylight Saving Time is A Reminder to Change<br />

Clocks” – Andrew Doble receives some timely<br />

advice from Florida’s Village Daily Sun<br />

one “female” model – which was,<br />

predictably, pink. Feedback pauses<br />

here to spare a thought for all the<br />

women who have been toiling with<br />

unsuitably gendered knives until now.<br />

Taken to task, the company<br />

quickly announced that the offending<br />

classification would be cut from<br />

their website.<br />

IAN WITHAM writes in with a<br />

money-saving tip. “Those herbal<br />

remedies that contain none of<br />

the advertised herbs will not be<br />

wasted,” (12 March) he says. “They<br />

can be relabelled and sold as<br />

homoeopathic remedies.”<br />

WHAT mires lie in wait for scientists<br />

who stray from their field of expertise.<br />

Famed astrophysicist Neil deGrasse<br />

Tyson got bogged down earlier this<br />

month when he tweeted: “If there<br />

were ever a species for whom sex<br />

hurt, it surely went extinct long ago.”<br />

Biologists quickly directed the<br />

space scientist to the many examples<br />

of painful sex, from barbed penises to<br />

traumatic insemination. In the face of<br />

many angry ornithologists shouting<br />

about duck vaginas, Tyson dialled<br />

back on his first tweet and offered an<br />

olive branch to the life sciences with<br />

another aphorism: “If you have a gene<br />

for celibacy, you didn’t inherit it.”<br />

Oh dear. May Feedback offer one in<br />

reply: “It’s better for an astrophysicist<br />

to remain silent on the subject of<br />

biology and be thought a fool, than to<br />

open his mouth and remove all doubt.”<br />

A PRESS flyer from Alan Dolan,<br />

Lanzarote-based respiratory guru<br />

to the stars, invites Feedback’s<br />

colleague to his next breathing<br />

retreat, “a powerful and intensive<br />

five days in which to relax”, by,<br />

err, breathing.<br />

But no ordinary breathing<br />

of course, this is Conscious<br />

Breathing, “a powerful and<br />

safe way to infuse the body with<br />

oxygen”. By wresting control of<br />

respiration from your brainstem –<br />

which Feedback notes has been<br />

managing it competently and<br />

continuously since the day you<br />

were born – Alan says you will<br />

enjoy a bingo card of vaguely<br />

worded benefits, such as higher<br />

levels of consciousness, reenergised<br />

systems, and a detox<br />

for every level of your being.<br />

“I’m sceptical,” admits our<br />

colleague, “but I think I need to be<br />

sent to Lanzarote to investigate.”<br />

<strong>THE</strong> apple doesn’t fall far from the<br />

tree: “Your mention of Lucy de la<br />

Pasture (5 March) reminds me of the<br />

novelist Mrs Henry de la Pasture,”<br />

writes Griselda Mussett. “Her<br />

daughter Esmée was also a novelist,<br />

and chose the name Delafield to mark<br />

the distinction between them.”<br />

A DENTAL firm is offering Glyn<br />

Williams “new ways to replace<br />

your teeth with digital<br />

technology”. Aside from this<br />

sounding very uncomfortable,<br />

Feedback thinks it would be a<br />

chore having to upgrade your<br />

mouth every two years.<br />

IN CONTRAST to the UK, drug<br />

law reform in the US is of a more<br />

permissive kind, fuelling a<br />

commodities market in cannabis, but<br />

so far, possession is still illegal in Ohio.<br />

However, you could be forgiven<br />

for wondering if the state’s leading<br />

gardening supplies manufacturer,<br />

The Scott’s Miracle Gro Company,<br />

is planning to diversify its business<br />

portfolio. A recent online advert for<br />

the company’s lawn seed ran with the<br />

tagline “Grass: it smells good. It feels<br />

good. It looks good. It is good.”<br />

You can send stories to Feedback by<br />

email at feedback@newscientist.com.<br />

Please include your home address.<br />

This week’s and past Feedbacks can<br />

be seen on our website.<br />

56 | NewScientist | 2 April 2016


<strong>THE</strong> LAST <strong>WORD</strong><br />

Last words past and present at newscientist.com/lastword<br />

Atomic bonds<br />

On an atomic level, how do Post-it<br />

notes stick to things?<br />

Post-it notes are a classic<br />

application of polymer chemistry.<br />

Funnily enough, the stickiness in<br />

question was discovered when<br />

Spencer Silver was trying to<br />

produce an incredibly strong<br />

adhesive in 1968. Instead, he<br />

produced an incredibly weak<br />

one, but most discoveries are<br />

accidents, so who is going<br />

to complain? Perhaps just<br />

students like myself as we<br />

stick up reminders of our<br />

exam dates and assignments.<br />

The glue used in Post-it notes<br />

is a pressure-sensitive adhesive.<br />

This means you only need to<br />

apply light pressure to stick the<br />

“The adhesive in Post-it<br />

notes was discovered<br />

when trying to produce an<br />

incredibly strong adhesive”<br />

note to something. The bond<br />

between the note and the surface<br />

is formed through a fine balance<br />

between flow and resistance to<br />

it. The adhesive can flow just<br />

enough to fill tiny crevices on<br />

the surface, but will resist flow<br />

enough to remain there. This<br />

produces the bond between the<br />

note and the surface.<br />

If we zoom in further, we can<br />

see that on a molecular level, the<br />

biggest contributors to the bond<br />

strength are van der Waals forces.<br />

These are created when a molecule<br />

has more of its electrons on one<br />

side than the other, producing a<br />

dipole (like a tiny magnet). This<br />

induces the opposite dipole in<br />

another molecule nearby and the<br />

two stick to each other. Van der<br />

Waals forces are normally weak,<br />

but they increase in strength as<br />

the size of the molecules grows.<br />

Bradley Clarke<br />

Brighton, East Sussex, UK<br />

Post-it adhesive sticks in<br />

much the same way as any<br />

other pressure-sensitive contact<br />

adhesive: through a combination<br />

of van der Waals forces, a decent<br />

balance of cohesion (the glue<br />

molecules sticking to each other)<br />

and adhesion (sticking to<br />

everything else), and good contact<br />

with the microscopic topography<br />

of the target surface.<br />

The more interesting<br />

question is how the notes peel off<br />

harmlessly. In practice, peeling<br />

leaves microscopic traces of<br />

Post-it glue on the target surface,<br />

but those are generally too small<br />

to cause visible damage. The<br />

secret is the molecular structure<br />

of the polymer, which forms a<br />

delicate network that links<br />

relatively large lumps together.<br />

Imagine it as being like a tennis<br />

net with sticky balls attached at<br />

intervals over most of its surface.<br />

The Post-it paper soaks up and<br />

holds powerfully onto one full<br />

surface of the adhesive mass (the<br />

tennis ball), but only one cheek of<br />

each sphere (or ball) sticks out,<br />

just touching the other surface.<br />

This has two important effects:<br />

ensuring that cohesive forces<br />

greatly exceed adhesive ones, and<br />

that peeling the paper off the<br />

target pulls on only the next ball<br />

in line – each requiring only a<br />

small force at a concentrated<br />

point, almost like undoing a zip<br />

tooth by tooth. Strong contact<br />

adhesives are different in that<br />

they spread the peeling forces<br />

over as wide an area as possible.<br />

They make it hard to pull any<br />

point free without fighting all<br />

the neighbouring adhesive<br />

material at the same time.<br />

Jon Richfield,<br />

Somerset West, South Africa<br />

Liquid gold<br />

I recently saw vodka in the<br />

supermarket with real gold leaf flakes<br />

in it. What caught my eye was that the<br />

gold flakes were distributed uniformly<br />

throughout the bottle. Gold is much<br />

denser than water, so why don’t they<br />

sink to the bottom?<br />

(Continued)<br />

One product that displays the<br />

behaviour described is Smirnoff<br />

Gold Cinnamon Flavoured<br />

Liqueur. If a bottle of this is rotated<br />

gently through about 45 degrees<br />

clockwise, the gold flakes follow<br />

the clockwise motion, but will<br />

then “rebound” anticlockwise<br />

when you stop. You can often<br />

observe similar rebounding if you<br />

stir a bowl of soup. This is not the<br />

behaviour of a Newtonian fluid,<br />

so the bottle probably contains<br />

something other than the usual<br />

constituents – perhaps some<br />

gelling agent.<br />

The gelatinous motion of the<br />

bottle’s contents is more<br />

reminiscent of a weak Bingham<br />

plastic, a material that remains<br />

rigid until it experiences a<br />

sufficient level of shear stress<br />

to start behaving as a viscous fluid<br />

(for example, mayonnaise).<br />

This can be confirmed by<br />

shaking the bottle and observing<br />

the motion of the air bubbles:<br />

as they rise, you can clearly see<br />

that they are threading their way<br />

through an invisible solid matrix,<br />

and some bubbles even become<br />

trapped in it.<br />

Terry Collins<br />

Harrogate, North Yorkshire, UK<br />

This week’s<br />

questions<br />

CASE LAW<br />

Do neatly folded clothes take<br />

up less luggage space? Logic<br />

suggests that just stuffing<br />

them in – which is my favoured<br />

approach – would take up the<br />

same space, or perhaps even<br />

less if you use a bit of pressure.<br />

Practice suggests otherwise.<br />

Ben Calascione<br />

London, UK<br />

SURF’S UP<br />

Surfers are often heard to say, on<br />

a day of meagre waves, that one<br />

should wait for the tide to turn<br />

because the waves will get bigger<br />

when the tide is “on the push”. Is<br />

there any reason to believe that<br />

waves will increase in height with<br />

an incoming tide?<br />

Colin Risner<br />

St Austell, Cornwall, UK<br />

The writers of answers that are published<br />

in the magazine will receive a cheque for<br />

£25 (or US$ equivalent). Answers should<br />

be concise. We reserve the right to edit<br />

items for clarity and style. Please include a<br />

daytime telephone number and an email<br />

address if you have one. New Scientist<br />

retains total editorial control over the<br />

published content.<br />

Reed Business Information Ltd<br />

reserves all rights to reuse all question<br />

and answer material that has been<br />

submitted by readers in any medium<br />

or in any format and at any time in the<br />

future.<br />

Send questions and answers to<br />

The Last Word, New Scientist, 110 High<br />

Holborn, London WC1V 6EU, UK, by email<br />

to lastword@newscientist.com or visit<br />

www.newscientist.com/topic/lastword<br />

(please include a postal address in order<br />

to receive payment for answers).<br />

Unanswered questions can also be found<br />

at this URL.<br />

Question<br />

Everything<br />

The latest book of science<br />

questions: unpredictable<br />

and entertaining. Expect<br />

the unexpected<br />

Available from booksellers and at<br />

newscientist.com/questioneverything


Professor Dame Carol Robinson<br />

2015 Laureate for United Kingdom<br />

By Brigitte Lacombe<br />

Science<br />

needs<br />

women<br />

Dame Carol Robinson, Professor of Chemistry at Oxford University, invented a ground-breaking<br />

L’ORÉAL<br />

UNESCO<br />

AWARDS<br />

method for studying how membrane proteins function, which play a critical role in the human body.<br />

Throughout the world, exceptional women are at the heart of major scientific advances.<br />

For 17 years, L’Oréal has been running the L’Oréal-UNESCO For Women In Science programme,<br />

honouring exceptional women from around the world. Over 2000 women from over 100 countries<br />

have received our support to continue to move science forward and inspire future generations.<br />

JOIN US ON FACEBOOK.COM/FORWOMENINSCIENCE

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!