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LimsLinkCDS - Vialis

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Case Study 112<br />

International Customer Creates Sequences in<br />

LimsLink CDS Instead of ChemStation and<br />

Reduces Setup Time<br />

Challenge<br />

An international pharmaceutical company was<br />

implementing both a new LIMS, Applied Biosystems<br />

SQL*LIMS ® , and a new CDS, ChemStation Plus ® .<br />

They wanted to have an interface between these two<br />

applications that would transfer sample results being<br />

run in a lab at one location to their main LIMS server<br />

which was running at another location, in another<br />

country. A Wide Area Network (WAN) connects the two<br />

locations.<br />

As they were already introducing two new applications<br />

in the lab, they wanted a solution that did not require<br />

the user having to learn and operate another piece of<br />

software. To keep the interface as simple as possible<br />

they wanted to have the analysts build their sequences<br />

in ChemStation Plus.<br />

Solution<br />

IDM-LimsLink CDS from Applied Biosystems was chosen<br />

to create the interface between SQL*LIMS and the<br />

ChemStation Plus Chromatography Data System. An<br />

Application Specialist from Labtronics visited the<br />

customer’s site to review their interface requirements<br />

and to install a prototype interface.<br />

Although the original intention was to continue creating<br />

sequences in ChemStation Plus, as soon as the<br />

customer saw the prototype, they quickly realized that<br />

IDM-LimsLink CDS could easily automate sequence<br />

creation in a way that would save the analysts a lot of<br />

time.<br />

IDM-LimsLink CDS includes a configurable ChemStation<br />

Plus interface that makes automation of sequence<br />

creation easy to set up and easy for the analysts to<br />

use.<br />

To set up the interface, a template with a series of<br />

check boxes and drop down menus is used to<br />

configure the ChemStation Plus parameters such as<br />

DSN Name, Instrument Method, Calibration Method,<br />

Sequence Parameters, etc. that are used to create the<br />

sequence. The template is designed to reflect the look<br />

and feel of ChemStation Plus and to use the same<br />

terminology as the CDS. For anyone who is familiar<br />

with ChemStation Plus, setup of the automated<br />

sequence creation is a very clear and straightforward<br />

process.<br />

At run time, the interface that the analyst uses to<br />

create the sequence also uses the ChemStation Plus<br />

look and feel and terminology, allowing the analyst to<br />

use the interface with minimal training. The automated<br />

process queries SQL*LIMS for a worklist of samples<br />

that are scheduled to be run for a test. The IDM-<br />

LimsLink CDS Expansion Function then takes that<br />

sample worklist, automatically adds in standards, and<br />

the complete sequence is transferred directly to<br />

ChemStation Plus.<br />

Using IDM-LimsLink CDS to automate sequence creation<br />

was clearly going to reduce the amount of time that the<br />

analysts spent manually building sequences in<br />

ChemStation Plus, without making the interface<br />

complex or difficult to work with.<br />

Case Study 112 1


International Customer Creates Sequences in LimsLink CDS Instead of ChemStation and Reduces Setup Time<br />

Using IDM-LimsLink CDS to report ChemStore results to<br />

a LIMS does not require any intervention at all on the<br />

part of the analyst. Working in the background IDM-<br />

LimsLink CDS automatically polls the ChemStore Oracle<br />

database at set time intervals. Any results that have<br />

been approved since the last query are automatically<br />

reported directly to LIMS. The whole process is<br />

automatic. Within minutes of approving results, they<br />

are available in the LIMS.<br />

Through their evaluation of the prototype interface, the<br />

company realized that IDM-LimsLink CDS would be able<br />

to provide them with an interface between<br />

ChemStation Plus and SQL*LIMS that not only met but<br />

exceeded their original expectations.<br />

Not only would they be able to automatically report<br />

results to LIMS without any intervention by the<br />

analysts, they would also benefit from the time saved<br />

by automating sequence creation. Because the<br />

interface incorporates the look and feel of<br />

ChemStation Plus, analysts would be very comfortable<br />

using it with minimal training.<br />

Based on the success of the prototype interface, IDM-<br />

LimsLink CDS interface was put into production.<br />

2<br />

Results<br />

IDM-LimsLink CDS is now automatically creating<br />

sequences and collecting results generated by 15 GCs<br />

that are continually running samples, 8 hours per day.<br />

The approved results are automatically collected and<br />

transferred over the Wide Area Network (WAN) to the<br />

main SQL*LIMS server. Sample results show up in the<br />

LIMS within minutes of being approved in ChemStation<br />

Plus.<br />

Benefits<br />

• Analysts can use the interface with minimal training<br />

• Automated sequence creation saves analysts setup<br />

time<br />

• Sample results are automatically reported to LIMS<br />

within minutes of being approved<br />

North America • Labtronics Inc. • Tel: (519) 767-1061 • Fax: (519) 836-4431 • E-mail: info@labtronics.com<br />

Europe • Labtronics B.V. • Tel: + 31 (0) 182 551243 • Fax: + 31 (0) 182 551270 • E-mail: EuroInfo@labtronics.com<br />

www.labtronics.com<br />

Case Study 112

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