Impaired glucose-induced glucagon suppression after partial ...

Figure legends:
Figure 1: Plasma concentrations of glucose (a), insulin (b), glucagon (c), and C-peptide (d) in
36 patients (18 males, 18 females) examined before (filled symbols) and after partial
pancreatectomy (open symbols). At t = 0 min, an oral glucose load (75g) was ingested. Data
are presented as means ± SEM. P-values Statistics were carried-out using paired repeated
measures ANOVA and denote A: Overall differences between the experiments, B: differences
over the time course and AB: differences between the experiments over the time course.
Asterisks indicate significant (p < 0.05) differences at individual time points versus control
subjects (one-way ANOVA).
Figure 2: Changes (�) in glucagon concentrations (calculated as mean glucagon
concentrations from t = 15 to t = 240 min minus basal glucagon levels) after the oral ingestion
of 75 g glucose in 36 patients (18 males, 18 females) examined before (filled symbols) and
after partial pancreatectomy (open symbols). Statistics were carried-out using paired t-tests.
Figure 3: Linear regression analysis between the changes (�) in glucagon concentrations
(calculated as mean glucagon concentrations from t = 15 to t = 240 min minus basal glucagon
levels) and the respective changes in insulin (A) and C-peptide concentrations (B) after the
oral ingestion of 75 g glucose in 36 patients (18 males, 18 females) examined before (filled
symbols) and after partial pancreatectomy (open symbols). Dashed lines indicate the
respective upper and lower 95 % confidence intervals. r = correlation coefficient.
Figure 4: Plasma glucagon concentrations in 24 patients undergoing pancreatic head
resection (A) and 12 patients undergoing pancreatic tail resection (B) examined before (filled
symbols) and after surgery (open symbols). At t = 0 min, an oral glucose load (75g) was
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