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West Newsmagazine 4-5-17

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50 I MATURE FOCUS I<br />

April 5, 20<strong>17</strong><br />

WEST NEWSMAGAZINE<br />

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MATURE FOCUS, from page 48<br />

benefits against other risks – such as those<br />

for cancer and blood clots – when deciding<br />

whether to use the therapy.<br />

@WESTNEWSMAG<br />

WESTNEWSMAGAZINE.COM<br />

Multiple medication risks<br />

The many chronic health conditions<br />

people face as they age often means they are<br />

prescribed multiple medications. When older<br />

adults take five or more medicines, which<br />

is called “polypharmacy” by health experts,<br />

the risk for harmful side effects increases. A<br />

recent analysis of a large German study of<br />

older adults found that polypharmacy was<br />

linked to increased frailty – characterized<br />

by weakness, decreased endurance and<br />

decreased ability to function. Frailty can,<br />

in turn, increase the risk for falls, disability<br />

and even death.<br />

The researchers examined information<br />

from nearly 2,000 older adults in Germany<br />

who participated in the ESTHER study,<br />

which began in 2000. People in the study<br />

were between 50 and 75 years old when<br />

it began, and follow-ups occurred after<br />

two, five, eight and 11 years. At the eightyear<br />

mark, doctors visited the participants<br />

at their homes for a geriatric assessment,<br />

which included a look at all the medications<br />

participants were taking – both prescription<br />

and over the counter. Based on those assessments,<br />

they placed participants into three<br />

groups:<br />

• People who took from zero to four medicines<br />

[non-polypharmacy]<br />

• People who took five to nine medicines<br />

[polypharmacy]<br />

• People who took 10 or more medicines<br />

[hyper-polypharmacy]<br />

After adjusting for differences in patients’<br />

histories, including illnesses, and excluding<br />

medicines and supplements not known to<br />

cause side effects, the research team found<br />

that seniors at risk for frailty, as well as those<br />

who were already frail, were more likely to be<br />

in the polypharmacy or hyper-polypharmacy<br />

groups. Those who took between five and<br />

nine medicines were 1.5 times more likely<br />

to become frail within three years compared<br />

with people who took fewer than five. People<br />

taking more than 10 medicines had twice the<br />

risk of near-term frailty compared to the nonpolypharmacy<br />

group.<br />

The researchers concluded that when<br />

possible, reducing multiple prescriptions<br />

for older adults is a promising approach<br />

to lessen the risks for frailty. “In a perfect<br />

world, your physician would talk about your<br />

medications with a pharmacist and a geriatrician.<br />

This might help to reduce avoidable<br />

multiple drug prescriptions and possibly<br />

also lessen medication-induced risks for<br />

See MATURE FOCUS, page 52<br />

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April 27<br />

20<strong>17</strong><br />

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Be thankful for your life, spend time in nature, breathe deeply, let go of your worries, forgive<br />

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