ISCAGUARD ® Preservatives for Personal Care - ISCA UK Ltd

13
Iscaguard ®
PPM
Iscaguard ®
PPM is an optimised blend of methylparaben
and propylparaben in phenoxyethanol giving the
advantages of broad-spectrum activity and ease of liquid
handling.
Iscaguard ®
PPM is compatible with most personal care
ingredients and the presence of phenoxyethanol reduces,
or overcomes the inactivation of parabens exhibited by
some nonionic emulsifiers when parabens are used
alone. In formulations with a high protein content,
it may be necessary to use a higher concentration of
Iscaguard ®
PPM compared with a similar formulation
with no protein present.
At typical use concentrations of 0.3 – 1.0%,
Iscaguard ®
PPM is non-irritant to skin, eyes and mucous
membranes.
Iscaguard ®
PPM has application in all categories of
personal care products and retains its activity over the
range pH 3 – 8.
Regulatory Status
Iscaguard ®
PPM is permitted for use in personal care
products in the European Union (maximum 1.39%),
the USA (safe as used) and Japan (maximum 1.39%).
INCI name: phenoxyethanol, methylparaben,
propylparaben.
Using Iscaguard ®
PPM
Iscaguard ®
PPM is soluble in water at approximately
0.5%, but may be incorporated at higher concentrations
into formulations containing surfactants, oils and waxes.
Prolonged heating at elevated temperatures is not
recommended, but Iscaguard ®
PPM may be added
immediately after emulsification in hot processes.
ISCA Iscaguard ®
Preservative Blends
Table 29
Solubility of Iscaguard ®
PPM (% w/w @ 25°C)
Water Approx. 0.5%
Propylene glycol Miscible
Butylene glycol Miscible
Isopropyl myristate Miscible
Table 30
Antimicrobial activity of Iscaguard ®
PPM
Microorganism Minimum inhibitory
concentration (%)
Pseudomonas aeruginosa 0.35
Escherichia coli 0.26
Proteus vulgaris 0.27
Staphylococcus aureus 0.29
Bacillus cereus 0.22
Enterococcus faecium 0.32
Candida albicans 0.16
Saccharomyces cerevisiae 0.12
Aspergillus niger 0.15