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Báo cáo khoa học: Hydrogels as Drug Delivery Systems (Hệ dẫn truyền thuốc Hydogels)

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III. THE SYSTHESIS OF HYDROGELS, THE WAYS TO LOAD DRUGS INTO<br />

HYDROGELS AND THE RELEASE OF DRUGS FROM HYDROGELS<br />

3.2. Preparation of drug-loaded hydrogels<br />

• Powdered samples of Pc-poly(NaAAco-AAm),<br />

hydrogel (1 g ± 0.0001),<br />

were accurately weighted and<br />

immersed in an alkaline solution of<br />

ibuprofen (IBU, 0.54 g dissolved in 50<br />

mL distilled water) at 0˚C for 25 h.<br />

• The swollen hydrogels loaded with<br />

drug were placed in a vacuum oven and<br />

dried under vacuum at 37˚C.<br />

Ibuprofen (IBU)<br />

• Mohammad Sadeghi<br />

- Journal of Biomaterials and Nanobiotechnology, 2011, 2, 36-40. DOI:10.4236/jbnb.2011.21005<br />

33

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