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Acne and Rosacea Charity Training Manual

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Topical retinoids<br />

Retinoids work by normalizing keratinocyte growth <strong>and</strong> are therefore used in conditions in which keratinocyte growth is abnormal. Systemic retinoids are use in<br />

psoriasis, the ichthyoses <strong>and</strong> acne. Topical retinoids are the agents generally used in acne.<br />

In the UK we have a limited number of topical retinoids <strong>and</strong> the majority of them are only available on prescription:<br />

0.1% isotretinoin – marketed as Isotrex gel or in combination with 2%erythromycin as Isotrexin<br />

gel.<br />

0.025% tretinoin – marketed with 4% erythromycin as Aknemycin plus lotion or with 1%<br />

clindamycin as Treclin gel. Retin A was discontinued some years ago but still can be<br />

purchased online.<br />

0.1%adapelene – marketed as Differin gel or cream or with 3% benzoyl peroxide marketed as<br />

Epiduo<br />

0.05% tretinoin is available on private prescriptions marketed Airol cream or Ketrel cream. Beware of on line products which may not have the same effect.

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