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Acne and Rosacea Charity Training Manual

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Scientific studies have shown that the NLite laser has no effects on bacterial numbers in the skin <strong>and</strong> no effect on sebum production. A single treatment,<br />

however, increases local production of transforming growth factor (TGF)by 1500%.<br />

TGF has three main biological effects:<br />

• Down regulates inflammatory cytokine in the skin<br />

• Up-regulates collagen production by fibroblasts<br />

• Induces regulatory T cells<br />

Increase in TGF at 3 <strong>and</strong> 24 hours after a single<br />

treatment with NLite laser<br />

It thus reduces inflammation, can increase collagen production, which would help scarring <strong>and</strong> could eventually induce regulatory T cell which could lead<br />

to tolerisation of the antigens that are causing the acne <strong>and</strong> result in resolution of the acne.

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