Healthy RGV Issue 113
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HEALTHY LIFESTYLE · APRIL 2018<br />
drinking can’t kill brain cells as previously believed,<br />
but it does damage the dendrites. These are<br />
the branch-like ends of the brain cells. They<br />
are key components in passing messages from<br />
one neuron to another. Any degradation of<br />
the dendrites may cause significant cognitive<br />
impairment.<br />
The research also suggests that any<br />
dendrite damage may be reverse<br />
with specific, targeted therapies and<br />
training, but there are no guarantees<br />
that those treatments will work in every<br />
case. Differing levels have damage can<br />
result in different outcomes.<br />
FIVE NEW TYPES OF DIABETES<br />
Could Mean Targeted Treatment<br />
for Thousands of Patients<br />
For decades, diabetes has been classified as either Type 1 or Type 2 diabetes, but recently<br />
Swedish researchers have identified five distinct types of the disease and offers the<br />
possibility of targeted treatments for patients. Some of these five types can be more<br />
dangerous than the types of diabetes we’ve long known about. The study dug deeper to<br />
look for specific characteristics.<br />
Together, researchers have created a new<br />
classification system to help medical professionals<br />
identify those who would be at most risk for<br />
complications and may one day allow medical<br />
professionals to treat patients on a more<br />
personalized scale with much more effective<br />
treatments.<br />
From the researchers’ analysis, they were able<br />
to identify five distinct clusters of diabetes that<br />
have distinct characteristics. SIRD, Severe Insulin-<br />
Resistant Diabetes, involved the highest levels<br />
of insulin resistance and offered the highest risk<br />
of diabetic kidney disease. MOD, Mild Obesity-<br />
Related Diabetes, is the most benign of the new<br />
classifications of diabetes. MARD, Mild Age-Related<br />
Diabetes, is another benign form of diabetes.<br />
SIDD, Severe Insulin-Deficient Diabetes solely<br />
effects young adults with poor metabolic control.<br />
Finally, Severe Autoimmune Diabetes overlaps<br />
with what we currently know as Type 1 Diabetes.<br />
What these new classifications tell us is that it is<br />
possible to help identify those people at higher<br />
risk of complication and will give doctors a<br />
better guide for their treatment choice for their<br />
patients, especially for those suffering from the<br />
most severe forms of this disease – SIDD, Severe<br />
Insulin Deficient Diabetes, and SIRD, Severe<br />
Insulin-Resistant Diabetes. The risk of kidney<br />
complications is substantially increased with SIRD.<br />
With SIDD, the risk of diabetic retinopathy is<br />
higher. With this new-found knowledge, doctors<br />
could target individuals who fall into these<br />
categories and intensify their treatment regimes.<br />
In addition to those who meet the criteria for<br />
these classifications, a new classification system<br />
could benefit those who’ve suffered with diabetes<br />
1 or 2 for many years. It would allow doctors<br />
to specifically target certain segments of their<br />
disease and could give them a clearer path<br />
forward.<br />
This new classification system promotes the<br />
combination of different measurements to form<br />
a much more specific diagnosis and a targeted<br />
treatment plan by going beyond the simple<br />
glucose levels and looking at other factors. It is a<br />
precision oriented finding that could have lasting<br />
results for thousands of people around the world.<br />
In their opinion, this new system could represent<br />
a bold, new step in identifying and managing this<br />
deadly disease. The potential benefits for patients<br />
could be life-changing for patients worldwide.<br />
THE CORRELATION BETWEEN DRINKING<br />
HEAVILY AND BRAIN HEALTH (ALCOHOL<br />
AWARENESS MONTH):<br />
For years, research scientists and the medical<br />
community have known that there are negative<br />
long-term effects of heavy alcohol consumption,<br />
but until recently, they’d not yet studied with<br />
overconsumption of alcohol does to the brain<br />
long-term. Recent studies have pointed to<br />
significant brain damage as a result of heavy<br />
alcohol consumption. They’ve found that heavy<br />
Wernicke-Korsakoff Syndrome is another brain<br />
disorder that alcoholics could suffer from. In<br />
this condition, memory impairment, significant<br />
confusion, eye paralysis, and decreasing levels<br />
of muscle coordination significantly lessens the<br />
quality of life for those affected. In contrast to<br />
the previously discussed condition, this syndrome<br />
does not lead to brain cell death because it isn’t<br />
the result of the alcohol specifically. It occurs due<br />
to a thiamine deficiency.<br />
Thiamine, an important B vitamin, is crucial<br />
to neuron health. Consuming large quantities<br />
of alcohol leads to a thiamine deficiency<br />
by disrupting the body’s ability to absorb<br />
it. Alcoholics tend to drink more of their<br />
calories, thus, making them malnourished. That<br />
malnourishment adds to the depletion of thiamine<br />
reserves in the body.<br />
For years, we’ve been led to believe that brain cells<br />
are destroyed with high alcohol consumption.<br />
That’s a myth. There’s no evidence that moderate<br />
alcohol consumption kills brain cells or damages<br />
them in any way. In order to actually kill brain<br />
cells, one would have to consume a fatal amount<br />
of alcohol, thus, killing themselves in the process.<br />
While it’s now noted that there can be significant<br />
brain damage, none of the current evidence points<br />
to any actual brain cell damage. However, as noted<br />
previously, there is a strong correlation between<br />
consuming large quantities of alcohol and major<br />
impairments. There is also strong evidence that<br />
heavy consumption of alcohol leads to a vast array<br />
of social and socioeconomic problems.<br />
As with any potential harmful substance, there<br />
are risks that need to be considered. Follow the<br />
healthcare guidelines to avoid these complications.<br />
If you believe you might have an alcohol problem,<br />
seek help before it’s too late. Much of the damage<br />
done as a result of heavy drinking cannot be<br />
reversed. Be proactive in your healthcare and seek<br />
help when needed. Rampant alcohol consumption<br />
may be seen as a harmless norm, but healthcare<br />
professionals and those struck with significant<br />
impairments know all too well just how life-altering<br />
the seemingly harmless substance can be. For<br />
more information about alcohol and how it can<br />
affect you, seek counsel from your healthcare<br />
provider and get the answers and resources you<br />
need to live a long, full life.<br />
26 HEALTHY MAGAZINE