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Healthy RGV Issue 113

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HEALTHY LIFESTYLE · APRIL 2018<br />

drinking can’t kill brain cells as previously believed,<br />

but it does damage the dendrites. These are<br />

the branch-like ends of the brain cells. They<br />

are key components in passing messages from<br />

one neuron to another. Any degradation of<br />

the dendrites may cause significant cognitive<br />

impairment.<br />

The research also suggests that any<br />

dendrite damage may be reverse<br />

with specific, targeted therapies and<br />

training, but there are no guarantees<br />

that those treatments will work in every<br />

case. Differing levels have damage can<br />

result in different outcomes.<br />

FIVE NEW TYPES OF DIABETES<br />

Could Mean Targeted Treatment<br />

for Thousands of Patients<br />

For decades, diabetes has been classified as either Type 1 or Type 2 diabetes, but recently<br />

Swedish researchers have identified five distinct types of the disease and offers the<br />

possibility of targeted treatments for patients. Some of these five types can be more<br />

dangerous than the types of diabetes we’ve long known about. The study dug deeper to<br />

look for specific characteristics.<br />

Together, researchers have created a new<br />

classification system to help medical professionals<br />

identify those who would be at most risk for<br />

complications and may one day allow medical<br />

professionals to treat patients on a more<br />

personalized scale with much more effective<br />

treatments.<br />

From the researchers’ analysis, they were able<br />

to identify five distinct clusters of diabetes that<br />

have distinct characteristics. SIRD, Severe Insulin-<br />

Resistant Diabetes, involved the highest levels<br />

of insulin resistance and offered the highest risk<br />

of diabetic kidney disease. MOD, Mild Obesity-<br />

Related Diabetes, is the most benign of the new<br />

classifications of diabetes. MARD, Mild Age-Related<br />

Diabetes, is another benign form of diabetes.<br />

SIDD, Severe Insulin-Deficient Diabetes solely<br />

effects young adults with poor metabolic control.<br />

Finally, Severe Autoimmune Diabetes overlaps<br />

with what we currently know as Type 1 Diabetes.<br />

What these new classifications tell us is that it is<br />

possible to help identify those people at higher<br />

risk of complication and will give doctors a<br />

better guide for their treatment choice for their<br />

patients, especially for those suffering from the<br />

most severe forms of this disease – SIDD, Severe<br />

Insulin Deficient Diabetes, and SIRD, Severe<br />

Insulin-Resistant Diabetes. The risk of kidney<br />

complications is substantially increased with SIRD.<br />

With SIDD, the risk of diabetic retinopathy is<br />

higher. With this new-found knowledge, doctors<br />

could target individuals who fall into these<br />

categories and intensify their treatment regimes.<br />

In addition to those who meet the criteria for<br />

these classifications, a new classification system<br />

could benefit those who’ve suffered with diabetes<br />

1 or 2 for many years. It would allow doctors<br />

to specifically target certain segments of their<br />

disease and could give them a clearer path<br />

forward.<br />

This new classification system promotes the<br />

combination of different measurements to form<br />

a much more specific diagnosis and a targeted<br />

treatment plan by going beyond the simple<br />

glucose levels and looking at other factors. It is a<br />

precision oriented finding that could have lasting<br />

results for thousands of people around the world.<br />

In their opinion, this new system could represent<br />

a bold, new step in identifying and managing this<br />

deadly disease. The potential benefits for patients<br />

could be life-changing for patients worldwide.<br />

THE CORRELATION BETWEEN DRINKING<br />

HEAVILY AND BRAIN HEALTH (ALCOHOL<br />

AWARENESS MONTH):<br />

For years, research scientists and the medical<br />

community have known that there are negative<br />

long-term effects of heavy alcohol consumption,<br />

but until recently, they’d not yet studied with<br />

overconsumption of alcohol does to the brain<br />

long-term. Recent studies have pointed to<br />

significant brain damage as a result of heavy<br />

alcohol consumption. They’ve found that heavy<br />

Wernicke-Korsakoff Syndrome is another brain<br />

disorder that alcoholics could suffer from. In<br />

this condition, memory impairment, significant<br />

confusion, eye paralysis, and decreasing levels<br />

of muscle coordination significantly lessens the<br />

quality of life for those affected. In contrast to<br />

the previously discussed condition, this syndrome<br />

does not lead to brain cell death because it isn’t<br />

the result of the alcohol specifically. It occurs due<br />

to a thiamine deficiency.<br />

Thiamine, an important B vitamin, is crucial<br />

to neuron health. Consuming large quantities<br />

of alcohol leads to a thiamine deficiency<br />

by disrupting the body’s ability to absorb<br />

it. Alcoholics tend to drink more of their<br />

calories, thus, making them malnourished. That<br />

malnourishment adds to the depletion of thiamine<br />

reserves in the body.<br />

For years, we’ve been led to believe that brain cells<br />

are destroyed with high alcohol consumption.<br />

That’s a myth. There’s no evidence that moderate<br />

alcohol consumption kills brain cells or damages<br />

them in any way. In order to actually kill brain<br />

cells, one would have to consume a fatal amount<br />

of alcohol, thus, killing themselves in the process.<br />

While it’s now noted that there can be significant<br />

brain damage, none of the current evidence points<br />

to any actual brain cell damage. However, as noted<br />

previously, there is a strong correlation between<br />

consuming large quantities of alcohol and major<br />

impairments. There is also strong evidence that<br />

heavy consumption of alcohol leads to a vast array<br />

of social and socioeconomic problems.<br />

As with any potential harmful substance, there<br />

are risks that need to be considered. Follow the<br />

healthcare guidelines to avoid these complications.<br />

If you believe you might have an alcohol problem,<br />

seek help before it’s too late. Much of the damage<br />

done as a result of heavy drinking cannot be<br />

reversed. Be proactive in your healthcare and seek<br />

help when needed. Rampant alcohol consumption<br />

may be seen as a harmless norm, but healthcare<br />

professionals and those struck with significant<br />

impairments know all too well just how life-altering<br />

the seemingly harmless substance can be. For<br />

more information about alcohol and how it can<br />

affect you, seek counsel from your healthcare<br />

provider and get the answers and resources you<br />

need to live a long, full life.<br />

26 HEALTHY MAGAZINE

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