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New Orbit Magazine Online: Issue 03, June 2018

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though viable and in many ways a healthy and<br />

suitable child, is set aside for a chance at a<br />

genetically superior randomisation of traits.<br />

When we combine the inevitable trend of<br />

failing to conceive naturally, being unable to<br />

pay for indefinite rounds of fertility treatment,<br />

and opting to take their single publicly funded<br />

round of IVF, it is easy to see how the story in<br />

Forecast for April could soon become a<br />

relatively commonplace heartache.<br />

Unlike the more radical conceptions of<br />

designer babies, PGD does not involve directly<br />

altering the human genome; rather, it<br />

increases the probability of parents creating a<br />

more desirable combination of their own<br />

existing genes. PGD has generally been used<br />

to assist parents to have children with reduced<br />

risk of disease and other disorders that may<br />

affect quality of life, therefore helping to<br />

remove such hereditary afflictions from the<br />

genepool. As far as PGD goes, the use of the<br />

technology to address genetic disorders that<br />

would critically affect child health and<br />

wellbeing has generally been well received.<br />

The ethical line is most often drawn when<br />

gene screening and editing technology is used<br />

to change or enhance aesthetic or non-health<br />

related traits such as eye colour or intelligence,<br />

especially when the ability to do this is a<br />

commodity able to be bought and sold.<br />

In 1992, Monique and Scott Collins crossed<br />

this line when they used PGD not to reduce<br />

the risk of genetic disease in a child, but to<br />

ensure that their child was a female (as the<br />

couple’s first two children were boys). This<br />

represented a landmark instance where the<br />

genetic makeup of a child had been selected<br />

for a purely aesthetic purpose – a “balanced”<br />

family – rather than ensuring that a viable<br />

human embryo was devoid of any detrimental<br />

genetic conditions. While the ability to choose<br />

a child’s gender may not seem like a major<br />

issue on an individual level, there are some<br />

potential and ethical issues with the practice<br />

becoming commonplace. Parents often have<br />

preferences their unborn child’s gender,<br />

particularly in cultural contexts where the sex<br />

of a child comes with significant advantages or<br />

disadvantages. In many cultures, families may<br />

prefer to have a boy as a means of ensuring<br />

their own future wellbeing, financial security,<br />

or even the propagation of a last name. This<br />

being said, those societies that value baby boys<br />

higher than baby girls may and often do fall<br />

prey to significant shows of sexism throughout<br />

a person’s adulthood, as well as creating<br />

population difficulties; young girls are<br />

abandoned, adopted out of the country or<br />

leave as adults, creating a disproportionately<br />

large adult male population and making the<br />

maintenance of society in the following<br />

generation all the more difficult. On top of<br />

this, the Collins case set a precedent through<br />

which other, less socially acceptable forms of<br />

superficial gene editing may occur, for traits<br />

that are more luxury than necessity.<br />

Despite being a landmark event in both<br />

addressing the causes of genetic disease and<br />

the path towards designer babies, PGD does<br />

have its limitations. Embryos selected during<br />

PGD can only possess traits encoded for in the<br />

genes of one or both parents, as all genetic<br />

material originates in the parents, even if<br />

conception has occurred via IVF. This means<br />

that it would be immensely unlikely for two<br />

blue eyed parents to have a brown eyed<br />

offspring, even if they were able to select from<br />

a panel of embryos as per PGD. The PGD<br />

procedure is further morally contentious as it<br />

requires the fertilisation of a number of<br />

embryos so that one “optimal” individual may<br />

be selected for implantation, and the<br />

remainder discarded; a practise we also see in<br />

Forecast for April. This has attracted the<br />

condemnation of both secular and religious<br />

thinkers that consider human life to begin at<br />

conception, or who would consider the

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