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Post Polio Syndrome - Management & Treatment in Primary

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4 <strong>Post</strong> <strong>Polio</strong> <strong>Syndrome</strong><br />

least 15 years. The symptoms may <strong>in</strong>clude the follow<strong>in</strong>g:<br />

● New muscle weakness.<br />

● Fatigue.<br />

● Muscle and jo<strong>in</strong>t pa<strong>in</strong>.<br />

● Atrophy of muscle.<br />

● New difficulties <strong>in</strong> activities of daily liv<strong>in</strong>g, particularly<br />

mobility related activities.<br />

● Cold <strong>in</strong>tolerance.<br />

● Sleep impairment.<br />

● Speech difficulties.<br />

● Dysphagia.<br />

● Respiratory dysfunction.<br />

The card<strong>in</strong>al symptom is new weakness. 5<br />

There is no laboratory test for PPS and <strong>in</strong> mak<strong>in</strong>g a diagnosis all other<br />

causes of these symptoms must be excluded. Therefore careful cl<strong>in</strong>ical<br />

evaluation us<strong>in</strong>g history, observation and exam<strong>in</strong>ation are the diagnostic<br />

tools required to elim<strong>in</strong>ate other disease entities. These causes <strong>in</strong>clude:<br />

● Natural effects of age.<br />

● Bone or jo<strong>in</strong>t problems due to deformity or “wear and tear”.<br />

● Other neurological disease.<br />

● Medical disease such as hypothyroidism.<br />

● Depression.<br />

S<strong>in</strong>ce this is a diagnosis of exclusion, laboratory tests such as FBC and<br />

TFTs will be important. Diagnostic imag<strong>in</strong>g such as jo<strong>in</strong>t X Rays or MRI<br />

scans of sp<strong>in</strong>al cord may be useful <strong>in</strong> rul<strong>in</strong>g out other causes. 6<br />

Referral to a consultant neurologist is usually essential for EMG,<br />

confirmation of the diagnosis and exclusion of other neurological and<br />

muscle disorders.<br />

Causes of <strong>Post</strong> <strong>Polio</strong> <strong>Syndrome</strong><br />

There is no def<strong>in</strong>ite explanation for the new symptoms associated with<br />

PPS but the most widely accepted theory is that of neuron fatigue. In<br />

PPS Mngt and Treat.<strong>in</strong>db 4 02/07/2007 16:07:49

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