January/February 2012 • Volume 10 • Issue 1 - SKINmed Journal

DIFFERIN ® (adapalene) LOTION, 0.1%—
THE ONLY RETINOID IN A LOTION FORMULATION
ON THE JOB
WITH GENTLE EFFICACY 1
RESULTS PATIENTS WANT IN A FORMULATION THAT DOES THE WORK—
PRESCRIBE DIFFERIN ® LOTION, 0.1% TODAY!
* A 12-week, multicenter, randomized, double-blind, parallel-group study of patients 12 to 18 years of age with acne vulgaris (N=1075).
† The most frequent adverse event reported was dryness. Erythema, stinging/burning, and scaling may also occur. 1
Important Safety Information
Differin ® Lotion, 0.1% is indicated for the topical treatment of acne vulgaris in patients 12 years and older. A thin fi lm of
Differin ® Lotion, 0.1% should be applied once per day to the face and other areas of the skin affected by acne. In clinical
trials, the most common adverse event (>1%) reported with use of Differin ® Lotion, 0.1% was mild to moderate skin dryness.
Erythema, scaling, stinging and burning may also occur. Excessive exposure to sunlight and sunlamps should be avoided
during treatment, and use of sunscreen products and protective clothing is recommended. Concomitant use of drying or
irritating topical products (like products containing resorcinol, salicylic acid or sulfur) should be used with caution. Instruct
patients to avoid the eyes, lips and mucous membranes when applying Differin ® Lotion, 0.1%, and not to apply to areas
that have been depilated with wax products. Differin ® Lotion, 0.1% has not been tested in pregnant or nursing women,
or with the elderly. Pregnancy Category C.
www.differin.com/HCP
Please see Brief Summary
of Prescribing Information
on adjacent page.
58.2% MEDIAN TOTAL LESION COUNT
REDUCTION BY WEEK 12 1 *
TOLERABILITY PROFILE SIMILAR TO
DIFFERIN ® (adapalene) CREAM, 0.1% 1†
AVAILABLE IN AN EASY-TO-USE
PUMP DISPENSER