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L.B. Bohle Innovativ 01/2019 EN

The customer magazine of the special maschine builder L.B. Bohle from Ennigerloh/Germany is published twice a year.

The customer magazine of the special maschine builder L.B. Bohle from Ennigerloh/Germany is published twice a year.

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The <strong>Bohle</strong> Uni Cone BUC ® is a specially slotted<br />

air distributor plate with a conical displacement<br />

cone. The design allows for completely fluidized<br />

particles.<br />

Since the fluidized particles or granules move tangentially<br />

at relatively low fluidization height, they do not require<br />

a high-volume expansion. This reduces the required<br />

installation height, saving costs and production space.<br />

Another advantage of the tangential design in plants<br />

from L.B. <strong>Bohle</strong> in Thorsten Wesselmann’s opinion is “that<br />

granulation, coating and drying can be carried out in a<br />

single system without altering the equipment setup.”<br />

L.B. <strong>Bohle</strong> developed the BFS fluid bed system with<br />

tangentially mounted spray nozzles and the patented<br />

<strong>Bohle</strong> Uni Cone BUC ® , a specially slotted air distributor<br />

plate with a conical displacement cone for batches of<br />

1 to 500 kg. Its pressure shock resistance of up<br />

to 12 bar makes the BFS the ideal choice for organic<br />

methods. Short product transfer times and efficient<br />

cleaning procedures offer additional potential savings<br />

in production time and cost. The geometrically similar<br />

structure simplifies scaling-up.<br />

A newly developed, protected multi-purpose valve<br />

directly above the distributor plate facilitates the dustfree<br />

suction and draining of the product container. The<br />

result for Wesselmann is “clear benefits with regards to<br />

ergonomics and cleaning that make the BFS stand out<br />

significantly from other fluid bed systems on the market.”<br />

Single-Pot Granulation<br />

Single-Pot granulation has been used in the pharmaceutical<br />

industry for many decades. With the VMA<br />

granulator, the mixing, high-shear wet granulation and<br />

drying (vacuum drying, carrier-gas drying, or drying by<br />

microwave heat) are all carried out in one container.<br />

Single-Pot granulators offer the following benefits:<br />

• Secure production within a closed container<br />

in a vacuum<br />

• High mixing and granulation efficiency (even<br />

for low doses of active agents at < 1%)<br />

• Drying at low temperatures<br />

• Small product contact surface for fast, easy<br />

cleaning and fast product changeover<br />

• Efficient solvent recovery through cooling water<br />

• Compact footprint for low space requirements<br />

The VMA product range includes classic mixer granulators<br />

with agitator and chopper units and a top-drive system.<br />

Two stirrers produce a shearing action and loosen the<br />

product. This helps to prevent clumping and ensures that<br />

the resulting granule is of optimum quality. According<br />

to Wesselmann, the GMP-compliant process tank with<br />

double jacket is “the heart of the VMA.” The main units<br />

are integrated in the granulation pot’s lid (Top-Drive). The<br />

process tank is emptied through a cone-shaped sieve<br />

(BTS 200) via the floor outlet into a container (IBC).<br />

Formula-controlled cleaning is carried out automatically.<br />

The VMA produces batch sizes from 20 to 960 litres and<br />

can be installed in potentially explosive environments.<br />

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