L.B. Bohle Innovativ 01/2019 EN
The customer magazine of the special maschine builder L.B. Bohle from Ennigerloh/Germany is published twice a year.
The customer magazine of the special maschine builder L.B. Bohle from Ennigerloh/Germany is published twice a year.
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
The <strong>Bohle</strong> Uni Cone BUC ® is a specially slotted<br />
air distributor plate with a conical displacement<br />
cone. The design allows for completely fluidized<br />
particles.<br />
Since the fluidized particles or granules move tangentially<br />
at relatively low fluidization height, they do not require<br />
a high-volume expansion. This reduces the required<br />
installation height, saving costs and production space.<br />
Another advantage of the tangential design in plants<br />
from L.B. <strong>Bohle</strong> in Thorsten Wesselmann’s opinion is “that<br />
granulation, coating and drying can be carried out in a<br />
single system without altering the equipment setup.”<br />
L.B. <strong>Bohle</strong> developed the BFS fluid bed system with<br />
tangentially mounted spray nozzles and the patented<br />
<strong>Bohle</strong> Uni Cone BUC ® , a specially slotted air distributor<br />
plate with a conical displacement cone for batches of<br />
1 to 500 kg. Its pressure shock resistance of up<br />
to 12 bar makes the BFS the ideal choice for organic<br />
methods. Short product transfer times and efficient<br />
cleaning procedures offer additional potential savings<br />
in production time and cost. The geometrically similar<br />
structure simplifies scaling-up.<br />
A newly developed, protected multi-purpose valve<br />
directly above the distributor plate facilitates the dustfree<br />
suction and draining of the product container. The<br />
result for Wesselmann is “clear benefits with regards to<br />
ergonomics and cleaning that make the BFS stand out<br />
significantly from other fluid bed systems on the market.”<br />
Single-Pot Granulation<br />
Single-Pot granulation has been used in the pharmaceutical<br />
industry for many decades. With the VMA<br />
granulator, the mixing, high-shear wet granulation and<br />
drying (vacuum drying, carrier-gas drying, or drying by<br />
microwave heat) are all carried out in one container.<br />
Single-Pot granulators offer the following benefits:<br />
• Secure production within a closed container<br />
in a vacuum<br />
• High mixing and granulation efficiency (even<br />
for low doses of active agents at < 1%)<br />
• Drying at low temperatures<br />
• Small product contact surface for fast, easy<br />
cleaning and fast product changeover<br />
• Efficient solvent recovery through cooling water<br />
• Compact footprint for low space requirements<br />
The VMA product range includes classic mixer granulators<br />
with agitator and chopper units and a top-drive system.<br />
Two stirrers produce a shearing action and loosen the<br />
product. This helps to prevent clumping and ensures that<br />
the resulting granule is of optimum quality. According<br />
to Wesselmann, the GMP-compliant process tank with<br />
double jacket is “the heart of the VMA.” The main units<br />
are integrated in the granulation pot’s lid (Top-Drive). The<br />
process tank is emptied through a cone-shaped sieve<br />
(BTS 200) via the floor outlet into a container (IBC).<br />
Formula-controlled cleaning is carried out automatically.<br />
The VMA produces batch sizes from 20 to 960 litres and<br />
can be installed in potentially explosive environments.<br />
6 INNOVATIV 1 | 2<strong>01</strong>9