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3D Contact Coculture<br />

T47D human breast cancer cells +/- human bone marrow stromal cells (bmMSC*)<br />

T47D only<br />

0 Gy<br />

T47D<br />

+ bmMSC<br />

*<br />

d 7<br />

d 14 d 19<br />

T47D only<br />

Growth inhibition<br />

through irradiation<br />

is mitigated by<br />

presence of<br />

bmMSC<br />

2 Gy<br />

T47D<br />

+ bmMSC<br />

*<br />

bmMSC<br />

aggregates (*)<br />

decrease in size<br />

over time.<br />

12

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