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transmission [13]. A cholera outbreak occurred in Haiti in

2010 when UN peacekeepers introduced the disease to the

earthquake devastated country, taking upwards of 10,000

lives. In 2018, there were cholera outbreaks in Yemen and

Somalia. Additionally, costs of outbreaks were estimated

to be $38.9-$64.2 million in 2005 [14]. Through further

studying this synergistic effect of quorum quenchers on

decreasing biofilm formation in V. harveyi, the mortality

rates and economic costs due to infectious diseases including

cholera can decrease in the future.

6. Acknowledgments

This work would not have been possible without the

endless guidance and support of my mentor, Amy Sheck.

I would like to extend gratitude to Kimberly Monahan, as

well. Also, I would like to thank Nick Koberstein for help

with statistical analysis. Furthermore, I would like to thank

the Research in Biology Classes of 2019 and 2020 for their

friendship and advice. Lastly, I am highly indebted to the

Glaxo Endowment to the North Carolina School of Science

and Mathematics for providing the funding for this

project.

7. References

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and cost-effectiveness of a single dose oral vaccination

campaign in Lusaka, Zambia. PLOS One, 14(5), e0215972.

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24 | 2019-2020 | Broad Street Scientific BIOLOGY

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