2017 Annual Report
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RESEARCH<br />
Viviane Labrie<br />
Viviane Labrie, Ph.D., studies<br />
the dynamic interplay between<br />
the human genome and<br />
its control system — the<br />
epigenome — to understand how<br />
neurodegenerative diseases start<br />
and progress in an effort to develop improved diagnostics<br />
and treatments. Labrie’s scientific pursuits have deepened<br />
understanding of conditions including Parkinson's,<br />
Alzheimer's, schizophrenia and lactose intolerance.<br />
She has also developed new methods for epigenome<br />
analysis. She is an assistant professor in the Center for<br />
Neurodegenerative Science.<br />
Jiyan Ma<br />
Jiyan Ma, Ph.D., studies<br />
abnormal proteins that cause<br />
neurodegenerative diseases,<br />
including Parkinson’s disease and<br />
prion diseases in humans and<br />
animals. His lab has developed<br />
new ways to understand how these proteins spread and<br />
cause diseases in humans and animals. The lab is also<br />
developing new approaches to diagnose and treat these<br />
devastating disorders. Ma is a professor in the Center for<br />
Neurodegenerative Science.<br />
Darren Moore<br />
Darren Moore, Ph.D., seeks<br />
new diagnostic and treatment<br />
approaches for Parkinson’s by<br />
investigating the inherited form of<br />
the disease, which accounts for 5<br />
to 10 percent of cases. He aims to<br />
translate the understanding of these genetic mutations<br />
into better treatments and new diagnostic tools for<br />
Parkinson’s, both inherited and non-inherited. Discoveries<br />
in Moore’s lab routinely elucidate the faulty molecular<br />
interactions that transform healthy, functioning neurons<br />
into diseased ones. Moore is a professor in the Center for<br />
Neurodegenerative Science.<br />
An award-winning year<br />
In <strong>2017</strong>, we celebrated the election of two of our<br />
own into prestigious societies, reflecting a lifetime of<br />
scientific achievement and reinforcing the Institute’s<br />
growing reputation as a home for innovative and<br />
impactful research.<br />
Dr. Peter Jones<br />
Chief Scientific Officer<br />
In addition to being awarded a 7-year, $7.8 million<br />
Outstanding Investigator Award from the National<br />
Institutes of Health, Dr. Jones was inducted into the<br />
American Academy of Arts & Sciences, an elite group that<br />
includes more than 250 Nobel laureates and 60 Pulitzer<br />
Prize winners. His election comes a year after he was<br />
named to the National Academy of Sciences.<br />
Dr. Stephen Baylin<br />
Director’s Scholar, VARI<br />
Co-Head of Cancer Biology, Johns Hopkins University<br />
Sidney Kimmel Comprehensive Cancer Center<br />
In May <strong>2017</strong>, Dr. Baylin became the third VARI-affiliated<br />
scientist to be elected to the prestigious National Academy<br />
of Sciences, which was founded in 1863 to advise the<br />
country on matters of science and technology. He joins<br />
Chief Scientific Officer Dr. Peter Jones and Dr. George<br />
Vande Woude, the Institute’s founding research director<br />
and distinguished scientific fellow, emeritus, among the<br />
society's storied ranks.<br />
With the elections of Drs. Jones and Baylin,<br />
VARI is now home to:<br />
3 members of the National Academy of Sciences<br />
3 members of the American Association for the<br />
Advancement of Science<br />
3 fellows of the American Association for Cancer Research<br />
2 members of the American Academy of Arts & Sciences<br />
VAN ANDEL INSTITUTE ANNUAL REPORT <strong>2017</strong> | 13