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2017 Annual Report

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A Letter from David Van Andel<br />

Dear Friends,<br />

This has been a year of extraordinary progress. Your<br />

generous support has helped us expand collaborations,<br />

achieve record levels of grant funding, publish more<br />

scientific advances than ever before and move closer to<br />

solving the mysteries surrounding some of humanity’s<br />

most devastating diseases.<br />

Our collaborations with researchers, educators and worldclass<br />

organizations have united us all with a common<br />

goal — to conquer diseases like cancer and Parkinson’s as<br />

quickly as possible. In Grand Rapids, we are discovering<br />

new ways to work together and build a critical mass of<br />

talent in the region. At the same time, we’re reaching<br />

out across the world, expanding collaborations with an<br />

impressive list of leading organizations, scientists and<br />

physicians.<br />

External recognition for the work we do has reached<br />

an all-time high and is reflected in the 37 new funding<br />

awards our scientists earned in <strong>2017</strong> totaling $27.7<br />

million, including $23.6 million in federal grants. We also<br />

broke another Van Andel Institute record in <strong>2017</strong>, with<br />

publications of scientific discoveries reaching an all-time<br />

high — 145 scientific papers, 132 of them peer-reviewed.<br />

Many of these studies were published in prestigious<br />

journals, such as Nature and Proceedings of the National<br />

Academy of Sciences, which reinforces the real-world impact<br />

of our work.<br />

Discoveries at VAI are providing important clues to better<br />

understand how our bodies function in health and disease.<br />

To aid in this endeavor, we installed one of the world’s most<br />

powerful microscopes, called a cryo-electron microscope.<br />

Already, it is revealing intricate molecular secrets, detailing<br />

three-dimensional, atomic-level portraits of life’s smallest<br />

components, which will help us understand disease and<br />

devise new targets for drug therapies. In addition, our<br />

Parkinson’s research is unlocking vital clues to how the<br />

disease may be triggered through inflammation and factors<br />

in the nose and gut.<br />

As we move into our third decade, we continue to push<br />

toward creating a better tomorrow through the work we do<br />

today. Your encouragement and generosity help us build<br />

that brighter future for generations to come. Thank you for<br />

all you’ve done to help us achieve these vital goals.<br />

Warmly,<br />

David Van Andel<br />

Van Andel Institute Chairman & CEO<br />

2 | VAN ANDEL INSTITUTE ANNUAL REPORT <strong>2017</strong>

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