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YSM Issue 86.3

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Ailments of a Graying

Population

By William Zhang

Carol Orlando was 65 when her family

members noticed the first changes.

Her social graces began giving way to

a detached brusqueness; her eclectic interests,

to grinding repetition. Gradually, she lost

the ability to care for herself, and her family

assumed roles as her caregivers: washing and

feeding her, and ultimately assisting with all

aspects of her life. Frontotemporal dementia,

an ailment of aging, was taking its toll.

As she descended deeper and deeper into

this malaise, her speech devolved: “your dad

taking dog for walk,” her daughter Wendy

DeLucca recalled her mother casually stating,

entirely unaware of the missing words. Then,

seemingly overnight, Carol — known to be a

caring mother with endless love to spread and

an endless love for conversation — suddenly

stopped talking.

Of course, not everyone progresses like

Carol. She is just one example, the tip of the

iceberg. Aging occurs on a broad spectrum

and can unfold with a variety of symptoms

and other age-related complications, such

as cancer or cardiovascular disease. Diseases

such as cancer, dementia, and cardiovascular

condititions are not developed exclusively as

symptoms of aging, but they do, in many cases,

have far higher rates of occurence among the

elderly. Even without these diseases, aging in

itself can be a taxing process. The vigor of

youth fades away to be replaced by a slower

pace of life, sore joints, deteriorating vision,

and the accompanying loss of touch with the

prevailing culture.

And while these natural changes may be

pressing enough, the mental inertia of dementia

— or the wear and tear of other age-associated

diseases — exponentially compounds

these challenges and exacerbates the difficulty

of the journey for the elderly. Insidiously, these

complications envelop individuals in a state of

spiraling impairment, as DeLucca can testify

to, gradually snuffing out their very essence.

So what can we do? For decades, researchers

have vigorously pursued avenues for the treatment

and prevention of age-related diseases,

yet solutions are still elusive. Recent investigations

run the gamut, from studies of neuronal

function and genome sequencing of centenarians

to examining the relationship between

diet and aging. “If we could find cures [for

Alzheimer’s and other aging-related diseases],

it would solve all of these problems,” Maria

Tomasetti, South Central Regional Director

of the Alzheimer’s Association, Connecticut

Chapter, explains, “so everyone is searching

for them feverishly.”

Though medical answers may be far in the

future, public health research on aging is concurrently

progressing. This work is carving out

solutions to address arguably more immediate

and equally important concerns of improving

quality of life for the elderly, especially while

the biological mechanisms of disease are still

being unveiled. Recent research in this field

points to gaps in our treatment of the elderly

and of age-related illnesses and challenges the

very underpinnings of how we perceive aging.

Seeing the Forest Among the Trees

It is clear that aging and its associated diseases

impact the elderly, and thus public health

has naturally focused on treating patient conditions.

But Joan Monin, Assistant Professor

of Epidemiology at the Yale School of Public

Health, argues that there is a missing factor in

the equation. Behind every elderly individual

facing health complications is at least one other

person taking them to their appointments,

assisting with household chores, aiding them

through the difficulties: the caregivers.

Informal caregivers — those who are unpaid

and are often spouses or children — deliver

80 - 90 percent of personal and medical care

to the elderly with chronic illnesses. Approxi-

14 Yale Scientific Magazine | April 2013 www.yalescientific.org

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