The Facts Karla M. Ku - The Methodist Hospital
The Facts Karla M. Ku - The Methodist Hospital
The Facts Karla M. Ku - The Methodist Hospital
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death and MI at 30 days in women<br />
presenting with acute ST elevation<br />
MI. 34 <strong>The</strong> CADILLAC trial examined<br />
the benefit of stent and abciximab in<br />
patients presenting within 12 hours of<br />
ST elevation MI and found a higher<br />
one-year mortality in women, possibly<br />
due to a longer time from symptom<br />
onset to percutaneous coronary inter-<br />
estimating the 10-Year Risk of CVd in Women<br />
Step 1. age<br />
Age, y 20-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79<br />
Points -7 -3 0 3 6 8 10 12 14 16<br />
Point<br />
Total<br />
10-y<br />
Risk, %<br />
HdL,<br />
mg/dL<br />
TC, mg/dL<br />
Age, y<br />
20-39<br />
Step 2. total Cholesterol<br />
Age, y<br />
40-49<br />
Age, y<br />
50-59<br />
vention (PCI). Women who received<br />
a stent demonstrated no difference in<br />
mortality when compared to angioplasty<br />
alone, however they had less<br />
major adverse cardiac events at one<br />
year. 31<br />
<strong>The</strong> outcome of women and men<br />
with unstable angina and non-Q-wave<br />
MI (NQWMI) was found to be similar<br />
Age, y<br />
60-69<br />
< 160 0 0 0 0 0<br />
160-199 4 3 2 1 1<br />
200-239 8 6 4 2 1<br />
240-279 11 8 5 3 2<br />
> 280 13 10 7 4 2<br />
Age, y<br />
20-39<br />
Step 3. smoking status<br />
Age, y<br />
40-49<br />
Age, y<br />
50-59<br />
Age, y<br />
60-69<br />
Nonsmoker 0 0 0 0 0<br />
Smoker 9 7 4 2 1<br />
Age, y<br />
70-79<br />
Age, y<br />
70-79<br />
Step 4. Hdl Step 5. Blood Pressure<br />
> 60 50-59 40-49 < 40<br />
Systolic BP,<br />
mm Hg<br />
Untreated Treated<br />
Points -1 0 1 2 < 120 0 0<br />
Step 6. add up the Points<br />
120-149 1 3<br />
130-139 2 4<br />
140-159 3 5<br />
> 160 4 6<br />
< 9 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 > 25<br />
< 1 1 1 1 1 2 2 3 4 5 6 8 11 14 17 22 27 > 30<br />
table 2. Steps 1-6 demonstrate how to estimate the 10-year risk for CVD in women.<br />
in the Thrombolysis in Myocardial<br />
Ischemia (TIMI) IIIB Registry. 28<br />
TACTICS: TIMI 18 demonstrated<br />
that, like men, women with NQWMI<br />
receiving both aspirin and tirofiban<br />
benefited from early invasive treatment.<br />
29 Likewise, women and men<br />
have similar prognoses after successful<br />
high-risk PCI. EPIC, EPILOGUE and<br />
10 II (1) 2006 | JMDHC
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