Download Product catalogue - TNI medical AG
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<strong>TNI</strong> ® Studies<br />
18<br />
Effect of an Open Nasal Cannula System (<strong>TNI</strong>) in<br />
hypercapnic respiratory failure in COPD patients<br />
G. Nilius¹, U. Domanski¹, K.J. Franke¹, K.H. Ruhle¹, H. Schneider²<br />
¹ HELIOS Klinik Hagen-Ambrock<br />
² John-Hopkins-University, Baltimore<br />
HELIOS Klinik Hagen<br />
Ambrock<br />
Klinik für Pneumologie<br />
breathing frequency<br />
without <strong>TNI</strong> with <strong>TNI</strong><br />
30,00<br />
25,00<br />
20,00<br />
15,00<br />
10,00<br />
5,00<br />
breathing frequency<br />
0,00<br />
1 2 3 4 5 6 7<br />
Patient No<br />
Methods:<br />
6 COPD patients and 1 patient with<br />
kyphoscoliosis (mean age 69.4 ± 15.5<br />
years, BMI 25.4 ± 10.3 kg/m²) with a<br />
hypercapnic respiratory failure without<br />
acidosis were treated with 2l/min oxygen<br />
insufflation for 1 hour and the <strong>TNI</strong> system<br />
for another 1 hour on a general<br />
pulmonary ward. The respiratory rate was<br />
constantly monitored and capillary blood<br />
gas analysis was performed at the<br />
beginning and the end of each phase.<br />
capillary blood gas analysis<br />
PCO2 without <strong>TNI</strong> PCO2 with <strong>TNI</strong><br />
Therapy<br />
Results:<br />
<strong>TNI</strong> reduced the breathing frequency from<br />
20.0 ± 4.3 (oxygen) to 18.1± 4.1 (<strong>TNI</strong>) per<br />
minute (p
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