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AFHU News Spring 2023

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PAGE 18<br />

AMERICAN FRIENDS OF THE HEBREW UNIVERSITY<br />

<strong>AFHU</strong> NEWS VOL. 30 PAGE 19<br />

Award-Winning HU Professor Shares<br />

<strong>News</strong> on Autism and Alzheimer’s<br />

Research<br />

Golda Meir Lectureship Award, and the Brettle<br />

Center for Research Award, as well as funding<br />

grants from the U.S. Department of Defense and<br />

the Israel Science Foundation.<br />

His research team has made significant progress<br />

in identifying genetically based autism—estimated<br />

to be 20% of all cases—but the causes of most<br />

autism cases remain a mystery. Prof. Amal’s lab<br />

is conducting research into possible pre-natal<br />

and environmental factors and working on new<br />

diagnostic tools to provide earlier identification<br />

and diagnosis of the illness. With the number of<br />

autism cases now standing at one in 30 births in<br />

the U.S. and one in 50 in Israel, hope for further<br />

progress is strong. Prof. Amal also spoke of his<br />

team’s success with Alzheimer’s disease. Recently,<br />

the Amal Lab found novel shared mechanisms<br />

between autism and Alzheimer’s, and Prof.<br />

Amal believes these findings may lead to new<br />

treatments for autism and Alzheimer’s patients.<br />

Einstein: The<br />

Man and His Mind<br />

An unprecedented visual biography of the<br />

iconic pioneer of modern physics, with signed<br />

photographs, letters, manuscripts, and more.<br />

The contributors to the book include Gary<br />

Berger, who assembled the collection over<br />

the past three decades; Michael DiRuggiero,<br />

owner of the Manhattan Rare Book Company,<br />

who specializes in the history of science with<br />

an emphasis on Einstein materials; and Hanoch<br />

Gutfreund, professor emeritus of theoretical<br />

physics at the Hebrew University of Jerusalem,<br />

where he is also the academic director of the<br />

Albert Einstein Archives.<br />

Prof. Haitham Amal is the recent recipient of a<br />

$400,000 research grant from the Philadelphia<br />

Eagles Autism Foundation. The grant was<br />

awarded to Prof. Amal for his groundbreaking<br />

research on the role of nitric oxide (NO) in<br />

Autism Spectrum Disorder (ASD) pathology.<br />

NO is a multifunctional signaling molecule and a<br />

neurotransmitter that plays an important role in<br />

physiological and pathophysiological processes,<br />

and Prof. Amal published the first research paper<br />

linking nitric oxide to ASD, a key step towards<br />

identifying a drug target for the disorder. Prof.<br />

Amal is the first researcher outside the U.S. to<br />

be awarded the prestigious grant and one of only<br />

nine grant recipients selected by a distinguished<br />

panel of nationally recognized U.S. researchers.<br />

In addition to the Philadelphia Eagles research<br />

grant, Prof. Amal is the recipient of the Wolf<br />

Foundation’s prestigious Krill Prize, the Prusiner-<br />

Abramsky Research Award in Clinical and Basic<br />

Neuroscience, the Kaye Innovation Award, the<br />

On Tuesday, January 31 Prof. Amal gave an update<br />

on his research during a dinner event hosted by<br />

American Friends of the Hebrew University and<br />

Cyma and Ed Satell at the Satell’s home in Jupiter,<br />

FL. In his presentation, the professor pointed out<br />

that little is understood about autism’s origins,<br />

triggers, or its location in the brain.<br />

Prof. Haitham Amal and Ed Satell<br />

Ph.D. students Shashank Kumar Ojha and Maryam Kartawy<br />

With his recognition from the Philadelphia Eagles<br />

Autism Foundation and his team’s impressive<br />

record of research breakthroughs, Prof. Amal<br />

remains optimistic, believing that further<br />

advances may be within our grasp.<br />

“Imagination is more<br />

important than knowledge.<br />

Knowledge is limited.<br />

Imagination encircles the<br />

world.” -Albert Einstein

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