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Karen L. Kotloff, MD Investiture Program

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KAREN L. KOTLOFF, <strong>MD</strong><br />

<strong>Karen</strong> L. <strong>Kotloff</strong>, <strong>MD</strong>, is a pediatric infectious<br />

disease physician who has made outstanding<br />

contributions to scientific research. She is a public<br />

health champion whose achievements have guided the<br />

development and implementation of interventions that<br />

have reduced preventable death and suffering in<br />

children throughout the world.<br />

Dr. <strong>Kotloff</strong> was born in Philadelphia, PA. She earned<br />

her BA from Washington University in St. Louis, MO<br />

in 1975 and her <strong>MD</strong> from Temple University School<br />

of Medicine in Philadelphia, PA in 1979, following in<br />

the footsteps of her father and maternal grandfather.<br />

She completed her residency in Pediatrics at the<br />

Children’s Hospital of Pittsburgh in 1983, and her<br />

fellowship in Infectious Disease at the UMSOM<br />

Center for Vaccine Development and Global Health<br />

(CVD). In 1987, she joined the UMSOM faculty, rising through the ranks to become Professor<br />

in 1999. She has secondary appointments in the Department of Medicine and the Department<br />

of Epidemiology and Preventive Medicine. She has served as Head of the Division of<br />

Infectious Disease and Tropical Pediatrics since 2012. In 2021, Dr. <strong>Kotloff</strong> was among the<br />

first group of faculty at University of Maryland, Baltimore (UMB) to receive the title of<br />

Distinguished Professor, the highest appointment bestowed upon a faculty member.<br />

Dr. <strong>Kotloff</strong> is an outstanding clinician-teacher who has cared for many ill children at UMMC<br />

for over 3 decades. She received the House Staff Teaching Award and has been cited as one of<br />

Baltimore Magazine’s Best Doctors. Her work as a clinician helped to shape the research and<br />

public health work she has pursued.<br />

Dr. <strong>Kotloff</strong> is recognized internationally for her research on diarrheal diseases, a leading cause<br />

of malnutrition and death in children throughout the world. She has conducted large<br />

multicenter epidemiologic studies in the U.S. and in multiple countries throughout sub-<br />

Saharan Africa and Asia to characterize the disease burden and identify the causes, risk<br />

factors, and health consequences of infectious diseases in children. This research has led to the<br />

introduction of life-saving vaccines that had been available for many years in the U.S., but<br />

many barriers had prevented them from reaching children in developing countries.<br />

She has worked extensively in Mali, West Africa, one of the world’s poorest countries with<br />

very high under-5 mortality rates. Currently, she is leading a randomized placebo-controlled<br />

trial in Mali among 50,000 pregnant women and their infants funded by the Bill & Melinda<br />

Gates Foundation. Known as SANTE, this trial will determine whether spaced doses of the<br />

antibiotic azithromycin reduces infant mortality. In recognition of her contributions to child<br />

health in Mali, she was awarded Chevalier de l’Ordre National du Mali (Knight of the<br />

National Order of Mali) by the President of Mali.<br />

Dr. <strong>Kotloff</strong>’s other focus is the clinical development of vaccines to control infectious diseases<br />

of public health importance. She has served as Principal Investigator of the NIAID-funded<br />

Vaccine Treatment and Evaluation Unit (VTEU) for 16 years. She has performed trials in all<br />

age groups for prevention of many infections including Shigella, cholera, typhoid, Clostridium<br />

difficile, anthrax, group A streptococcus, and influenza. When SARS-CoV-2 emerged, she led<br />

the Moderna trial at UMSOM. In addition, she served as the global co-Chair for the Novavax<br />

trial. She prioritized community outreach, establishing a new vaccine trial site at Casa de<br />

Maryland in Hyattsville, to ensure that strong data were available from those at highest risk of<br />

severe COVID-19. She serves as a technical expert and advisor on multiple national and<br />

international committees including the World Health Organization and the Vaccine and<br />

Related Biological Products Advisory Committee of the Food and Drug Administration from<br />

2014 to 2018. Her work has resulted in more than 350 published articles and book chapters.


WELCOME<br />

Heather S. Culp, JD<br />

Senior Vice President<br />

Chief Philanthropy Officer<br />

University of Maryland Medicine<br />

Steven J. Czinn, <strong>MD</strong><br />

The Drs. Rouben and Violet Jiji Endowed Professor<br />

Chair, Department of Pediatrics<br />

University of Maryland School of Medicine<br />

Director, University of Maryland Children's Hospital (UMCH)<br />

REMARKS<br />

Mark T. Gladwin, <strong>MD</strong><br />

Dean, University of Maryland School of Medicine<br />

Vice President for Medical Affairs, University of Maryland, Baltimore<br />

John Z. and Akiko K. Bowers Distinguished Professor<br />

DONOR RECOGNITION<br />

Mark T. Gladwin, <strong>MD</strong><br />

SPEAKERS<br />

Kathleen M. Neuzil, <strong>MD</strong>, MPH, FIDSA, FACP<br />

The Myron M. Levine, <strong>MD</strong>, DTPH Professor of Vaccinology<br />

Director, Center for Vaccine Development and Global Health<br />

Chief, Division of Geographic Medicine<br />

Professor, Departments of Medicine and Pediatrics<br />

University of Maryland School of Medicine<br />

James D. Campbell, <strong>MD</strong>, MS<br />

Professor, Department of Pediatrics, Division of Infectious Diseases and Tropical Pediatrics<br />

University of Maryland School of Medicine<br />

Samba Sow, <strong>MD</strong>, MSc, FASTMH<br />

Director General for National Institute of Public Health (INSP)<br />

Director General of the Center for Vaccine Development in Mali (CVD-Mali)<br />

Former Minister of Health<br />

Mali Ministry of Health and Social Development<br />

Adjunct Professor of Medicine at the University of Maryland School of Medicine (UM SOM)<br />

MEDAL PRESENTATION<br />

Mark T. Gladwin, <strong>MD</strong><br />

REMARKS<br />

<strong>Karen</strong> L. <strong>Kotloff</strong>, <strong>MD</strong><br />

The John A. Scholl, <strong>MD</strong> and Mary Louise Scholl, <strong>MD</strong> Professor of Pediatrics<br />

CLOSING REMARKS<br />

Steven J. Czinn, <strong>MD</strong>


T<br />

he first endowed professorships were established more than 500<br />

years ago with the creation of the Lady Margaret chairs in divinity<br />

at Oxford and Cambridge Universities. The original endowed<br />

chairs were sponsored by Lady Margaret, countess of Richmond,<br />

and grandmother of Henry VIII in 1502. Subsequently, private individuals<br />

began making financial contributions to establish other endowed<br />

professorships and chairs such as the Lucasian Chair of Mathematics, which<br />

Sir Isaac Newton held beginning in 1669. Professor Stephen Hawking, the<br />

internationally renowned physicist and recipient of the 2010 Presidential<br />

Medal of Freedom, was another prominent holder of this endowed chair.<br />

The honor associated with appointment to an endowed position has remained<br />

unchanged for the last 500 years and is recognized as one of the highest<br />

tributes that an academic institution can bestow upon its most distinguished<br />

faculty. These endowed professorships and chairs continue to reward<br />

exceptional scholars uninterrupted to the present time.<br />

The Office of Development is charged with securing private gifts to ensure the<br />

School’s tradition of excellence is sustained through robust research, clinical,<br />

and educational programs and initiatives. The University of Maryland School<br />

of Medicine is fortunate to have nearly 85 endowed chairs & professorships in<br />

various stages of completion and held by esteemed faculty members.


JOHN A. SCHOLL, <strong>MD</strong> AND<br />

MARY LOUISE SCHOLL, <strong>MD</strong><br />

John A. Scholl, <strong>MD</strong> and Mary Louise<br />

Scholl, <strong>MD</strong>, had exemplary and<br />

fascinating careers since receiving their<br />

degrees in Medicine from the University<br />

of Maryland Medical School in 1941<br />

and 1942, respectively. They were<br />

married in 1941.<br />

Dr. John Scholl attended West Point and also received a degree from West Virginia<br />

University before attending medical school at the University of Maryland. He<br />

interned at Mercy Hospital in Pittsburgh before serving with the U.S. Army Medical<br />

Corps stationed with the 105th Station Hospital in North Africa during World War<br />

II. After the war he received training in general surgery and neurosurgery at Ohio<br />

State University, followed by a neurosurgery fellowship at Massachusetts General<br />

Hospital. Scholl practiced neurosurgery in the Boston area until 1974 when<br />

they moved to Escondido, California. He was a first-class aviation medical<br />

examiner for the Federal Aviation Association until March 1996 when failing health<br />

forced his retirement.<br />

Dr. Mary Louise Scholl interned at Pittsburgh Medical Center and received<br />

residency training at Pittsburgh Children’s Hospital and Columbus Children’s<br />

Hospital. A pediatric neurology fellowship followed at both Columbus Children’s<br />

and Boston Children’s Hospital. She served on the faculty at Harvard Medical<br />

School from 1954 to 1971, and in 1962 developed the first CCG Lab at<br />

Massachusetts General Hospital. Seven years later, Dr. Scholl started the first<br />

comprehensive learning disabilities unit there. Upon their move to Escondido, she<br />

joined the faculty at the University of California San Diego as an associate clinical<br />

professor and medical director of the neuropsychological development center.<br />

Dr. John Scholl passed away on January 14, 1997, and Dr. Mary Louise Scholl<br />

joined him almost 10 years later on January 8, 2007.<br />

The gift that established this endowed professorship was originally named by Dr.<br />

Mary Louise Scholl in honor of her husband, Dr. John Scholl. Her name was added<br />

after her death by their family to honor them both.

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