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Successful 2003 Discovery Projects Grants by Institution - Australian ...

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discovered that the enzyme tyrosine hydroxylase undergoes a form of hierarchical phosphorylation not<br />

previously reported. Here we examine hierarchical phosphorylation in rat and human tyrosine<br />

hydroxylase and its functional consequence in intact cells. The approaches and methods developed will<br />

also be applicable to investigation of hierarchical phosphorylation in other proteins.<br />

DP0344762 Dr MR Fellows<br />

Title: Parameterized Algorithm Design and Complexity Analysis: New Methods and<br />

Strategic Applications in the FPT Algorithmic Server Project<br />

<strong>2003</strong> : $60,000<br />

2004 : $55,000<br />

2005 : $50,000<br />

***<br />

Category: 2804 - COMPUTATION THEORY AND MATHEMATICS<br />

Administering <strong>Institution</strong>: The University of Newcastle<br />

Summary:<br />

A fundamental discovery of the first decades of computer science is that completely efficient (polynomial<br />

time) algorithms probably do not exist for thousands of natural computational problems. The project will<br />

result in new methods for designing and analyzing algorithms for hard problems with natural parameters,<br />

and in improved algorithms for these problems.<br />

DP0343326 Dr GV Franks<br />

***<br />

Title: Nano-Particle Suspension Behaviour in Salt Solutions: Effect of Ion Hydration and<br />

Attractive Forces<br />

<strong>2003</strong> : $66,000<br />

2004 : $56,000<br />

2005 : $56,000<br />

Category: 2914 - MATERIALS ENGINEERING<br />

Administering <strong>Institution</strong>: The University of Newcastle<br />

Summary:<br />

Understanding and controlling the flow behaviour of nano-particle suspensions is crucial to the<br />

processing of ceramics with nano-scale features. Interparticle forces influence the flow behaviour and<br />

depend upon the the adsorption of ions to the particle's surface. The proposed research investigates the<br />

effect of ion hydration and surface type on ion adsorption, the resulting attractive forces and suspension<br />

flow behaviour. The outcomes of the project have potential for significant increase in fundamental<br />

understanding of the relationship between ions, surfaces and forces. The benefits of this knowledge<br />

include producing nano-ceramics with improved properties and better understanding biopolymer<br />

behaviour.<br />

DP0345779 Prof GC Goodwin Dr JA De Dona<br />

Title: Towards a unified theory of constrained control and estimation<br />

<strong>2003</strong> : $128,000<br />

2004 : $120,000<br />

2005 : $126,000<br />

***<br />

Category: 2301 - MATHEMATICS<br />

Administering <strong>Institution</strong>: The University of Newcastle<br />

Summary:<br />

The project will investigate the implications of duality and other connections between constrained control<br />

and estimation. We believe that the research will result in a richer understanding of these problems. In<br />

particular, we envisage an impact in at least four areas: (i) Computational issues, i.e., development of<br />

more efficient algorithms for constrained problems. (ii) Geometry of constrained problems, <strong>by</strong> extending<br />

recent results pertaining to constrained control to estimation problems. (iii) Problems with mixed<br />

constraints, for example, interval and finite set constraints. (iv) Fundamental limitations imposed <strong>by</strong><br />

constraints to filtering and control problems.

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