Potency and Tolerance of Calcitonin Stimulation with High Dose ...
Potency and Tolerance of Calcitonin Stimulation with High Dose ...
Potency and Tolerance of Calcitonin Stimulation with High Dose ...
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Tables<br />
Table 1. Subject characteristics at study entry <strong>and</strong> clinical side effects <strong>of</strong> pentagastrin <strong>and</strong><br />
calcium. FT3, free triiodothyronine; FT4, free thyroxine; SD, st<strong>and</strong>ard deviation;<br />
TSH, thyroid-stimulating hormone<br />
Characteristic Value<br />
Females, n (%) 25 (50%)<br />
Age, yr, mean ± SD (range) 33.1 ± 9.7 (23 - 57)<br />
Body mass index, kg/m², mean ± SD (range) 22.8 ± 3.0 (18.1- 33.1)<br />
Thyroid volume by ultrasound, mL, mean ± SD<br />
(normal range)<br />
11.0 ± 5.0 (5.0 - 24.0)<br />
TSH, mIU/L, mean ± SD (normal range) 1.6 ± 0.6 (0.3 - 4.0)<br />
FT3, pmol/mL, mean ± SD (normal range) 4.4 ± 0.7 (2.7 - 7.6)<br />
FT4, pmol/mL, mean ± SD (normal range) 17.6 ± 2.1 (11.0 – 23.0)<br />
Thyroperoxidase autoantibody titers, mean<br />
(normal range)<br />
Thyroglobulin autoantibody titers, mean (normal<br />
range)<br />
7.0 (0 - 100)<br />
20.6 (0 – 100)<br />
Calcium, mmol/L, mean ± SD (normal range) 2.4 ± 0.1 (2.0 - 2.7)<br />
Pentagastrin side effects (N = 50), incidence, %<br />
Retro/Substernal tightness / abdominal cramping<br />
Extremity paresthesia<br />
Feeling <strong>of</strong> warmth<br />
Dizziness<br />
Nausea, urge to micturate, salty metallic taste<br />
Pentagastrin side effect duration<br />
94%<br />
74%<br />
30%<br />
12%<br />
a few subjects each<br />
1-2 min<br />
11
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