Speakers - Sachs Associates

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CONTACT Carlos Paya Chief Executive Officer ADDRESS 1124 Columbia Street suite 700 Seattle, WA 98104 TELEPHONE 206-826-7910 FAX 206-682-0648 EMAIL carlos.paya@immunedesign.com YEAR FOUNDED 2008 Immune Design www.immunedesign.com FINANCIAL SUMMARY Since 2008 Immune Design has raised $52M from venture capital funding. COMPANY PROFILE Immune Design is a privately held biotechnology company based in Seattle, Washington and formed in 2008 to bring together some of the world’s leaders in the field of immunology, and their technologies, to develop therapeutic vaccines for the treatment of infectious and malignant disease. The company’s scientific founders are Dr. David Baltimore (Past President of Caltech, Rockefeller University, and the Whitehead Institute and the Co-Recipient of the 1975 Nobel Prize in Physiology or Medicine), Dr. Steven Reed (Past Co-founder and CSO of Corixa and Founder/CEO of the Infectious Diseases Research Institute), and Dr. Larry Corey (President and Director of the Fred Hutchinson Cancer Research Center and Professor of Medicine and Laboratory Medicine at the University of Washington). To date Immune Design has raised approximately $52 million from The Column Group, Alta Partners, Versant Ventures, and Proquest. Immune Design leverages its unique vaccine technologies to precisely control the activation and context of antigen presentation by dendritic cells in order to shape the desired adaptive immune response. The first technology is a novel adjuvant for recombinant protein antigen (rP)-based vaccines comprising Glucopyranosyl Lipid A (GLA), a synthetic TLR4 agonist, formulated in a stable 2% oil-in-water emulsion (SE). Adjuvants can play an important role in vaccine therapies by stimulating the immune system’s response to the target antigen. GLA is the first ‘designer adjuvant’ and was developed by Immune Design co-founder Dr. Steve Reed. To date GLA-SE has been safely administered in over 300 human subjects. Our second vaccine platform is a novel lentivirus-based vector, ID-LV (Immune Design-Lentiviral Vector). The prototype of ID-LV was developed by Immune Design co-founder, Dr. David Baltimore. ID-LV is unique in that it can stimulate the body’s own dendritic cells (DCs), the “sentinels” of the immune system, to produce any, and importantly, multiple antigens of interest in the same product configuration, effectively orchestrating the human immune system to respond to targeted diseases. Immune Design’s ID-LV and GLA-SE vaccine technologies are immunologically synergistic, as documented in animal models, and thus, have the potential to be used both alone and in combination to create the next generation of vaccines for diseases with unmet medical need. MANAGEMENT Carlos Paya, MD, PhD, Chief Executive Officer Wayne Gombotz, PhD, Chief Development Officer J Paul Rickey, VP, Finance and Administration t back :: next u WELCOME PHARMA LICENSING GROUPS SPEAKERS PRESENTING COMPANIES SUPPORTING ORGANISATIONS ORGANISERS
CONTACTS Kevin FitzGerald Chief Operating Officer Ghaz Mahdizadeh EA ADDRESS London BioScience Innovation Centre 2 Royal College Street London NW1 0NH TELEPHONE +44 020 7691 4908 EMAIL Kevin.FitzGerald @its-innovation.com Ghaz.mahdizadeh @its-innovation.com YEAR FOUNDED 2004 Immune Targeting Systems www.its-innovation.com FINANCIAL SUMMARY The Company is supported by leading investors including Novartis Venture Fund, HealthCap, Truffle Capital, SME Wholesale Finance and Esperante Ventures and has raised £14.5m to-date. The Company is currently seeking investors to participate in a series-B financing. COMPANY PROFILE Immune Targeting Systems is an emerging leader in the development of vaccine products that work by promoting T-cell responses against viruses and cancers (“T-cell vaccines”). The company’s lead product Flunisyn, currently in clinical development, is a novel T-cell vaccine which elicits potent cellular immune responses against multiple strains of influenza. The Company’s technology also supports a product portfolio which includes Hepsyn-B, an attractive therapeutic hepatitis B vaccine and T-cell vaccines against cancers. MANAGEMENT Kevin FitzGerald, PhD MBA, Chief Operating Officer • Serial life sciences entrepreneur with over twenty years’ experience within the biotechnology industry; • Scientific, commercial and strategic expertise; • CEO of F-star, founder & CEO of Isogenica and among the founding group of scientists at Cambridge Antibody Technology; • Capital-raising expertise (more than €30m raised to date); • Substantial business development experience (deals closed with Amgen, AstraZeneca, Boehringer Ingelheim, Centocor, GE Healthcare, Johnson & Johnson, Merck Serono, Pfizer, UCB-Celltech and Wyeth etc.). t back :: next u WELCOME PHARMA LICENSING GROUPS SPEAKERS PRESENTING COMPANIES SUPPORTING ORGANISATIONS ORGANISERS
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Events Diary For regular updates, s
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Speakers Alexey Eliseev, Managing D
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