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Speakers - Sachs Associates

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CONTACTS<br />

Carlos Buesa<br />

Chief Executive Officer<br />

Emili Torrell<br />

Business Development Officer<br />

ADDRESS<br />

C/San Ferran 74<br />

08940 Cornella de Llobregat<br />

(Barcelona), SPAIN<br />

TELEPHONE<br />

+34 93 515 13 13<br />

FAX<br />

+34 93 377 40 28<br />

EMAIL<br />

cbuesa@oryzon.com<br />

etorrell@oryzon.com<br />

info@oryzon.com<br />

YEAR FOUNDED<br />

2000<br />

ORYZON<br />

www.oryzon.com<br />

FINANCIAL SUMMARY<br />

Stage of funding<br />

5 Funding rounds from inception (15 M€ in total) + 15 M€ in Competitive Grants. Last funding (9M€) was<br />

accomplished in 2008. These funds were also matched with a set of competitive grants and long-term / nullvery<br />

soft rates public loans.<br />

Capital plans – IPO plans<br />

The Company will need a new round of funding (8-10M) in late 2012 early 2013 to keep the development of the<br />

programs to Phase I-II in full speed. The company is considering to get this funding either through C series or<br />

preIPO funding.<br />

Investors. The company has a French-Spanish VC firm NAJETI as main stakeholder from 2003. Other VCs<br />

having minor stakes are CORSABE, Invercat and Barcelona Empren. Several Spanish family offices and private<br />

minor investors are also present.<br />

COMPANY PROFILE<br />

Oryzon is a biomarker discovery company with a dual therapeutic pipeline in oncology and neurodegeneration.<br />

Founded in 2000, and venture backed from 2002, Oryzon has a strong focus in EPIGENETIC TARGETS with a<br />

special emphasis in Histone Lysine Demethylases being a global leader on Lysine Specific Demethylase-1 with<br />

a dominant IP position. LSD1 has been proposed as a target for oncology, viral diseases and neurodegeneration.<br />

Oryzon has two preclinical programs with different preclinical candidates LSD1i, one in ACUTE MIELOGENOUS<br />

LEUKAEMIA and the other in Huntington disease. Our inhibitors are highly potent in vitro (low nM) and in<br />

vivo (

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