Download MSDS of furfuryl alcohol - International Furan Chemicals BV
Download MSDS of furfuryl alcohol - International Furan Chemicals BV
Download MSDS of furfuryl alcohol - International Furan Chemicals BV
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EU SAFETY DATA SHEET<br />
according to Regulation (EC) N° 1907/2006 and 453/2010<br />
Furfuryl Alcohol<br />
11. TOXICOLOGICAL INFORMATION<br />
11.1<br />
Information on toxicological effects<br />
11.1.1 Acute toxicity<br />
LD50 (oral, rat) (mg/kg) 177<br />
LD50 (dermal, rabbit) (mg/kg) 400<br />
LC50 (inhalation, rat, 4 hours) (mg/l) 0,82 – 2,07<br />
11.1.2 Skin corrosion/irritation No evidence that the substance is irritating to skin.<br />
No classification warranted.<br />
11.1.3 Serious eye damage/irritation The substance is irritating to eyes.<br />
11.1.4 Respiratory or skin sensitization Concluded not to be sensitizing.<br />
11.1.5 Germ cell mutagenicity Concluded not be genotoxic in vivo.<br />
11.1.6 Carcinogenicity Suspected <strong>of</strong> causing cancer. Tumours incidence in rats<br />
and mice considered to be related to tissue damage<br />
resulting from repeat exposure and respiratory irritation<br />
i.e. represent conversion <strong>of</strong> highly specialized nasal<br />
epithelium to more resistant types <strong>of</strong> epithelium and<br />
represent adaptive responses to chronic irritation.<br />
11.1.7 Reproductive toxicity No evidence <strong>of</strong> adverse effects on reproduction or<br />
development.<br />
11.1.8 STOT- single exposure From acute toxicity studies, evident that the substance<br />
may cause respiratory irritation particularly to the upper<br />
respiratory tract and the nose.<br />
11.1.9 STOT- repeated exposure From repeated-dose toxicity studies, evident that the<br />
substance may cause respiratory irritation particularly to<br />
the upper respiratory tract and the nose. May cause<br />
damage to the respiratory system - through prolonged or<br />
repeated exposure.<br />
11.1.10 Aspiration hazard Does not present an aspiration hazard.<br />
11.1.11 Likely routes <strong>of</strong> exposure The substance may be absorbed into the body by<br />
inhalation, after ingestion and through the skin.<br />
12 ECOLOGICAL INFORMATION<br />
12.1<br />
12.2<br />
12.3<br />
Toxicity<br />
LC50 (fish, 96 hours) (mg/l) 362<br />
EC50 (Daphnia, 48 hours) (mg/l) 224<br />
IC50 (algae, 96 hours) (mg/l) 170<br />
Persistence and degradability<br />
Biodegradability Readily biodegradable.<br />
Oxygen demand<br />
– biological (5 days) in gO2/g (BOD5) 0,81<br />
– biological (20 days) in gO2/g (BOD20) Not available<br />
– chemical in gO2/g (COD) 1,75<br />
BOD5 : COD 0,46<br />
Bioaccumulative potential<br />
BCF (Bioconcentration factor)<br />
(conc. in organisms / conc. in water)<br />
0,96<br />
Risk <strong>of</strong> bio accumulation is low (BCF
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