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Treating Lipid Abnormalities Beyond LDL - Washington Hospital ...

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Increasing HDL By Infusion of HDL,<br />

Overexpression of the ApoA-I or LCAT Genes<br />

Decreases Atherosclerosis<br />

Infuse HDL<br />

Control<br />

HDL Infused<br />

Badimon et al J. Clin<br />

Invest 1990:85,1234-1241<br />

Increase A-I Gene<br />

Plump et al Proc Natl Acad<br />

Sci 1994:91, 9607- 9611.<br />

Increase LCAT Gene<br />

Hoeg et al Proc Natl Acad<br />

Sci 1996 93:11448- 11453

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