Treating Lipid Abnormalities Beyond LDL - Washington Hospital ...
Treating Lipid Abnormalities Beyond LDL - Washington Hospital ...
Treating Lipid Abnormalities Beyond LDL - Washington Hospital ...
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THE PYRAMID OF CVD<br />
TRIALS<br />
Very high cholesterol<br />
with CHD or MI<br />
Moderately high cholesterol<br />
in high-risk CHD or MI<br />
Normal Cholesterol<br />
with CHD or MI<br />
High cholesterol with<br />
NO CHD or MI<br />
No history of CHD or MI, average TG<br />
and <strong>LDL</strong>-C, but below average HDL-C<br />
Comparison of coronary clinical events with<br />
<strong>LDL</strong> reduction by pravastatin and atorvastatin<br />
No history of CVD with Normal <strong>LDL</strong> and Increased CRP<br />
4S<br />
PLAC I/II, KAPS, REGRESS<br />
CARE<br />
WOSCOPS<br />
AFCAPS/TexCAPS<br />
PROVE -IT<br />
JUPITER<br />
HPS Collaborative Group. Lancet. 2002;360(9326):7-22; LaRosa JC, et al. N Engl J Med. 2005;352(14):1425-1435; 4S Group. Lancet.<br />
1994;344(8934):1383-1389; Sacks FM, et al. N Engl J Med. 1996; 335(14):1001-1009; Shepherd J, et al. N Engl J Med. 1995; 333(20):1301-<br />
1307; Downs JR, et al. JAMA. 1998;279(20):1615-1622; Cannon CP, et al. N Engl J Med. 2004;350(15):1495-1504; Circulation.
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