Treating Lipid Abnormalities Beyond LDL - Washington Hospital ...
Treating Lipid Abnormalities Beyond LDL - Washington Hospital ...
Treating Lipid Abnormalities Beyond LDL - Washington Hospital ...
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ILLUMINATE: Investigation of <strong>Lipid</strong><br />
Level Management to Understand its<br />
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Impact in<br />
15, 067 patients<br />
Men and women<br />
Aged 45‐75 years<br />
250 sites in 7 countries<br />
CHD or risk equivalent V D L<br />
No HDL‐C level L restrictionL<br />
L<br />
Titrated statin dose D<br />
Primary End Point<br />
Composite of fatal CHD, nonfatal<br />
MI, stroke (fatal and non‐fatal and<br />
unstable angina requiring<br />
hospitalization<br />
Atherosclerotic Events<br />
T Day<br />
December 2, 2006<br />
Torcetrapib 60 mg + titrated<br />
atorvastatin dose<br />
Titrated atorvastatin dose<br />
H D<br />
L<br />
C E T P<br />
Proposed Duration<br />
4.5‐year 4.5 year follow‐up follow up or 1820<br />
clinical events<br />
Report out ~2010‐2011 ~2010 2011<br />
ILLUMINATE Trial Terminated
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