Sarcoidosis - Cleveland Clinic Center for Continuing Education
Sarcoidosis - Cleveland Clinic Center for Continuing Education
Sarcoidosis - Cleveland Clinic Center for Continuing Education
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Hypercalcemia in <strong>Sarcoidosis</strong><br />
• 1939 Harrel G: first description<br />
• 1979 Papapoulos SE: increased serum<br />
calcitriol (active Vit D3) is associated<br />
with hypercalcemia<br />
• 1981 Barbour G: site <strong>for</strong> overproduction of<br />
calcitriol must be extrarenal<br />
• 1983 Adams JS & Sharma OP puzzle solved:<br />
cultured AM in sarcoidosis are able to<br />
produce calcitriol