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Final Programme - iuphar

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FC15 Endothelium in health and disease<br />

Organized by the British Pharmacological Society<br />

Leaders: Christopher J Garland, (UK) & Arthur Weston, (UK)<br />

FC15.4 Drug development and novel therapeutic targets and approaches<br />

Chairs: Johannes-Peter Stasch, (Germany) & Harald Schmidt, (The Netherlands)<br />

09:30 - 09:55 FC15.4.1 Stimulators and activators of soluble guanylate cyclase: From bench to bedside<br />

Johannes-Peter Stasch, (Germany)<br />

09:55 - 10:20 FC15.4.2 Gaseous signalling molecules: the biological effects of hydrogen sulfide – comparison<br />

with nitric oxide<br />

Csaba Szabó, (USA)<br />

10:20 - 10:45 FC15.4.3 Therapeutic effects of enhancing endothelial nitric-oxide synthase (eNOS) expression and<br />

preventing eNOS uncoupling<br />

Ulrich Förstermann, (Germany), H Li<br />

10:45 - 11:15 COFFEE BREAK<br />

11:15 - 11:40 FC15.4.4 NOX 1, 2, 3 and counting: targeting oxidative stress<br />

Harald Schmidt, (The Netherlands), K Wingler, C Kleinschnitz<br />

11:40 - 11:55 FC15.4.5 Free Communication Presentation:<br />

Effects of K + channel blockers on the relaxation induced by nitric oxide (NO) donors in<br />

basilar artery from renal hypertensive 2K-1C rats<br />

Michele Paulo, (Brazil), J Vercesi, J Biazzotto, R da Silva, L Bendhack<br />

11:55 - 12:10 FC15.4.6 Free Communication Presentation:<br />

MicroRNA-27b rescues impaired endothelial progenitor cell-induced angiogenesis and<br />

wound healing via suppressing thrombospondin-1 in type 2 diabetes<br />

Alex Chen, (USA), J Wang,<br />

12:10 - 12:25 FC15.4.7 Free Communication Presentation:<br />

Co-activation of PKCdelta/ERK1/2 and p38 MAPK mediates angiotensin II-induced<br />

cyclooxygenase-2 up-regulation in endothelial cells and the clinical implications<br />

Siu Ling Wong, (PR China), CW Lau, WT Wong, A Xu, CL Au, X Yao, Y Huang<br />

154 Friday 23 July ■ 09:30 - 12:30 ■ Hall A3

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