Final Programme - iuphar

FC02 Transmembrane transport: Perspectives for disease
and drug discovery
Tue 037 Ivermectin activates Cys-loop ligand-gated chloride channels by interacting with the third
transmembrane domain
Timothy Lynagh, (Australia), T Webb, J Lynch
Tue 038 A role of α2 isoform of the Na,K-pump in mesenteric small arteries wall
Vladimir Matchkov, (Denmark), NM Nielsen, C Aalkjær
Tue 039 Expression and function of the organic cation transporter 3 (OCT3) in the human placenta
Karen May, (Germany), V Rozehnal, M Grube, M Zygmunt, HK Kroemer, W Siegmund
Tue 040 Effect of the P-glycoprotein on the intestinal absorption of herbal products associated with
antiretrovirals in mice
Joe Miantezila Basilua, (France), G Mamadou, N Limas Nzouzi, G Peytavin, B Eto
Tue 041 Impact of OATP1B1, OATP1B3 and ABCC2 on the hepatic uptake and pharmacokinetics of the
MRI-contrast agent Gd-EOB-DTPA in healthy volunteers
A Nassif, S Oswald, J-P Kühn, C Modess, N Hosten, Werner Siegmund (Germany)
Tue 042 Mitochondrial sodium/calcium exchanger as a new target to develop neuroprotective drugs
Santos Nicolau, (Spain), J Egea, M López, A García
Tue 043 Influence of ABCB1 C3435T polymorphism on the pharmacokinetics of ezetimibe and its glucuronide in
healthy subjects
Da-Hee Oh, (Republic Of South Korea), C-I Choi, J-W Bae, M-J Kim, C-G Jang, S-Y Lee
Tue 044 The role of OATP1B1 genetic variants in the disposition of pitavastatin in healthy Koreans
Da-Hee Oh, (Republic Of South Korea), C-I Choi, J-W Bae, M-J Kim, C-G Jang, S-Y Lee
Tue 045 Influence of efavirenz on the disposition and lipid-lowering effects of ezetimibe in healthy subjects
Stefan Oswald, (Germany), H Meyer zu Schwabedissen, A Nassif, C Modess, D Lütjohann, Z Desta,
H Kroemer, W Siegmund
Tue 046 SLC26 transporters are regulated via the [Cl-]i-sensitive Ste20p kinases
Hyun Woo Park, (South Korea), JH Nam, MG Lee
Tue 047 Modification of equilibrative nucleoside transporter 1 (ENT1) function by sulfhydryl reagents involves
cysteine residues in transmembrane regions 6 and 7
Jamie Park, (Canada), J Hammond
Tue 048 The expression of organic cation transporter mrna in cultured adult and neonatal rat astrocytes and
their possible functional role
Katja Perdan-Pirkmajer, (Slovenia), S Pirkmajer, Z Grubiè, M Krzan
Tue 049 Influence of rifampicin on pulmonary expression of ABCB1 and ABCC2 and on distribution of
clarithromycin into epithelial lining fluid and broncho-alveolar cells of foals
Jette Peters, (Germany), J Freyer, W Block, S Oswald, M Venner, W Siegmund
Tue 050 Effect of viral infection on hepatic and placental drug transporters and endogenous substrates in
pregnant rats
Vanja Petrovic, (Canada), M Piquette-Miller
Tue 051 Block of the IKr current by the HMG-CoA reductase inhibitor rosuvastatin is modulated by BCRP, MDR1
and OATP2B1 membrane drug-transporter activites
I Plante, M Frappier, F Belanger, Jacques Turgeon (Canada)
202 Tuesday 20 July ■ 13:00 - 14:00 ■ Poster Area