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55 VOLUME 86, NUMBER 15 APRIL 14, 2008 COVER STORY BATTLING BACTERIA As companies grapple with bacterial resistance and cost to discover antibiotics, doctors and drug firms worry about gram-negative bacteria. PAGES 15, 22 QUOTE OF THE WEEK “You can really do awesome things with a bachelor’s degree, and I think that sometimes that gets missed along the way.” JANINE VAN GEMERT, DEVELOPMENT CHEMIST, HUNTSMAN POLYURE- THANES PAGE 55 NEWS OF THE WEEK 8 ACS IN NEW ORLEANS National meeting was held jointly with the American Institute for Chemical Engineers. 9 NOVARTIS AND ALCON Pharma firm will pay billions for majority stake in Nestlé eye care unit. 9 REACH PREREGISTRATION Preventing disruptions in chemicals commerce is goal as EU regulation phases in. 10 TOXIC SOCKS Washing releases silver nanoparticles embedded in fabric to control odor. 10 TAKEDA BUYS MILLENNIUM Purchase for $8.8 billion furthers globalization of Japanese firm. 11 W.R. GRACE TO REEMERGE Settlement with asbestos claimants could bring the company out of bankruptcy. 11 ENERGY RESEARCH SYMPOSIUM Event for chemists and chemical engineers raises awareness of basic energy research needs. 12 CATALYTIC REACTIONS ON WATCH Infrared microspectroscopy monitors reactions in pores of zeolite crystals. 12 CECH TO LEAVE HHMI Biochemist will exit next spring; nationwide search for successor is under way. 13 FINE CHEMICALS IN JAPAN Trade show suggests Japanese pharma may be open to foreign suppliers. 13 ISOPRENE IN THE AIR Research indicates hydroxyl radicals are being recycled by jungle-emitted isoprene. BUSINESS 25 CONCENTRATES CENEAR 86 (15) 1–64 • ISSN 0009-2347 27 PAYING THE PRICE Soaring sulfur and sulfuric acid prices hit chemical c companies hard. 30 REICHHOLD REBOUNDS Previously a money loser, resins maker today is profitable with $1 billion in annual sales. 32 PETROCHEMICALS POWWOW Industry producers discuss high energy costs. GOVERNMENT & POLICY 34 CONCENTRATES 35 PROBING EPA House committee investigates industry bias in agency peer review. 37 HINDSIGHTS Employment rates continue to grow slightly, but other indicators reveal the U.S. jobs outlook is not so bright. SCIENCE & TECHNOLOGY 39 CONCENTRATES 40 MICROBIAL METEOROLOGY Bacteria in the atmosphere have proteins that nucleate ice, potentially initiating precipitation. 44 WHAT’S THAT STUFF? Dryer sheets soften fabrics, add fragrance, and reduce static cling. EMPLOYMENT 55 ADVANCED DEGREE OPTIONAL B.S. and M.S. chemists find challenging and diverse careers in the corporate sector. THE DEPARTMENTS 3 EDITOR’S PAGE 6 LETTERS 45 ACS COMMENT Serving the chemical, life sciences, and laboratory worlds 47 ACS NEWS 64 NEWSCRIPTS COVER: As bacteria evolve and resist current antibiotics (like Cubist’s daptomycin, shown), drug developers strive to bring new revenue generators to market. imagezoo THIS WEEK ON WWW.CEN-ONLINE.ORG ACS MEETING BLOG Catch up on blog posts from the national meeting at www. cenblog.org. PLUS: Read about industry concerns over FDA’s crackdown on antibiotic approval regulations.
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Joseph L. Kurz Lonedell, Mo. Kennet
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Christoph Ruchardt Freiburg, German
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employment outlook OPPORTUNITIES FO
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corporate team structures. In addit
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TRICIA MAY carve out a long career
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Chemistry NASA Goddard Space Flight
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SITUATIONS WANTED OTHER RESEARCH OR
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The best connections to keep your p
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