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2009 he established Collaborative Research in Art Science and Humanity<br />

(CRASH) at Curtin http://crash.curtin.edu.au<br />

HEALTH/BODY<br />

Sherryl Ryan<br />

Art under the microscope:artist and scientist observing cancer histology using a<br />

two-head compound microscope<br />

Culture at Work (CAW) is a Research Institute in Sydney founded in 2008 <strong>of</strong>fering<br />

collaborative art science residencies. Sherryl Ryan, artist founder <strong>of</strong> CAW and<br />

resident artist at the National Breast Cancer Foundation (NBCF), has an interest in<br />

breast cancer research. A/Pr<strong>of</strong>essor Chris Ormandy who leads The Mammary<br />

Development Group at the Cancer Program in the Garvan Institute has been<br />

collaborating with the artist on this pathway. In that context, the artist had the<br />

opportunity to visit the Garvan and to observe histology sections <strong>of</strong> mice<br />

mammary tissue with the scientist David Gallego-Ortega, PhD.<br />

Genetically engineered mice have allowed the investigators to examine the<br />

effects <strong>of</strong> specific genes on the development and progression <strong>of</strong> mammary<br />

tumours. In this study, biopsies collected from a luminal breast cancer model<br />

(PyMT) have been analysed. 5µm sections <strong>of</strong> paraffin embedded normal<br />

mammary glands and breast cancer tumour biopsies were stained using the<br />

Haematoxylin & Eosin technique (H&E) and inmunohistochemistry (IHC) labeling.<br />

These methods stain the cellular nuclei in blue and the cytoplasm and other<br />

extracellular compounds in a range <strong>of</strong> pink, in the IHC, the cellular markers will<br />

appear in brown. The histology sections were analysed and photographed using<br />

a two-head Leica Microsystems DM-E Compound microscope coupled to a<br />

high-resolution camera, collaboratively by the artist and the researcher a<br />

selection <strong>of</strong> images was performed. As a result, and besides the scientific interest<br />

<strong>of</strong> the images, a strong artistic imprinting is included in every picture. Discussions<br />

about the visual implications viewed within the histology sections between<br />

scientist and artist while observing through the two-head microscope created a<br />

new art science paradigm leading to complex analysis <strong>of</strong> how cancer may be<br />

connected to systems in the universe. An outcome <strong>of</strong> the collaborative research<br />

was an exhibition <strong>of</strong> photographs at CAW in March 2011.<br />

BIOGRAPHY<br />

Sherryl Ryan is a pr<strong>of</strong>essional artist from Melbourne and CEO Culture at Work. She<br />

studied Fine Art at RMIIT and a Post Grad Fine Art at COFA UNSW and Education<br />

at Victoria College Melbourne with a Masters in Education from UNSW. Sherryl<br />

has developed a research interest in Vygotsky, the relationship between artistic<br />

practice and science, creativity in thinking and learning and collaborations with<br />

46

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