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Optical Projection Tomography (OPT) - Biomedicum Imaging Unit ...

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Goals<br />

Quantitative modeling of mammalian organ development<br />

Specifically, can we understand the processes that turn Ainto<br />

B<br />

i.e. Mouse limb development (E10.75 � E12.25)<br />

A B<br />

36 hours<br />

To construct a 4D finite-element model<br />

we require quantitative data on:<br />

1) gene expression patterning 2) morphology 3) local tissue motion

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