Introducing the next generation of high-throughput plaque and ...

CTL-BioSpot Analyzers
The future of microdetection
Introducing the next generation
of high-throughput plaque and
colony counters
Traditionally, plaque and colony counting have been both
slow and inefficient. It takes days, if not weeks, before
plaques and colonies grow large enough to be seen using
traditional methods. What’s more, they had to be grown
within Petri dishes and other low-throughput plate formats,
each of which had to be counted by eye or separately
loaded into a plate reader for analysis.
Such inefficiency is a thing of the past,
thanks to CTL’s new BioSpot Analyzers.
BioSpot Analyzers allow much smaller plaques and
colonies to be detected, thus dramatically reducing the
amount of growth time required. What’s more, because
they support multiwell plate formats, they can also scan
multiple samples in rapid succession.
Reduced growth times +
high-throughput plates =
unprecedented speed
and efficiency
Versatility
BioSpot Analyzers can be used for a
wide range of applications —microbial
colony counting, viral plaque counting,
clonogenic assays, genotoxic assays,
stem cell assays, and more. With the
purchase of CTL’s ImmunoSpot ® 5.0
software package, each BioSpot
instrument can also be used for analyzing
ELISPOT assays — both single- and
double-color!
Cellular Technology Limited, 20521 Chagrin Blvd. Shaker Heights, OH 44122
Tel: (216) 791-5084 or (888) 791-4005
The BioSpot Analyzer portfolio
can accommodate a wide range of
budgets and scientific needs. Every
model incorporates the finest components
and CTL’s advanced analysis
tools, thereby ensuring that accuracy
and precision are not compromised.
In addition, each BioSpot model
employs CTL’s proprietary SmartLux
or BioLux illumination systems.
These technologies allow the user to
customize the illumination techniques,
thereby optmizing them for a wide
range of assay types.
CTL-BioSpot S5 Core
The S5 Core Analyzer is ideally suited
for dealing with limited plate formats.
It can be configured to provide fixed
magnification for either 6-, 12-, 24-,
or 96-well plates, generating superior
image quality for whichever format is
selected. In addition, its combination
of high-performance forelighting and
backlighting provides sharp contrast
for a wide range of assay types.
E-mail: info@immunospot.com
Web: www.immunospot.com
CTL-BioSpot S5 Macro
The S5 Macro Analyzer combines
high performance with unparalleled
versatility. This model is ideally suited
for counting colonies as small 100
μm in diameter, and it can handle
100mm Petri dishes, 96-well plates,
and all formats in between. It is the
best choice for customers who work
with different assay types and need
plate scanning versatility to match.
CTL-BioSpot S5 Micro
When you need the utmost in speed
and efficiency, the S5 Micro is the
instrument of choice. Its revolutionary
BioLux lighting system allows
even colonies as small as 25 μm in
diameter to be seen. In addition, the
S5 Micro’s optics permit seamless
switching between the 24-, 48-, and
96-well plate formats. They also allow
the user to zoom in for even higher
magnification, counting objects less
than 10 μm in diameter... including
individual stained cells!

CTL-BioSpot ® S5 UV
The S5 UV Analyzer is CTL’s most
advanced model. In addition to
providing high-resolution visible light
analysis, it also incorporates a UV
light source for detecting fluoroescent
cells. It can even accommodate a
wide range of other fluorescent and
visible light applications—ELISPOT,
FluoroSpot, cell cycle analysis, cell
viability tests, apoptosis tests, and
much more!
The automated filter changer allows
up to six wavelengths of fluorescent
analysis. Its high-magnification lens
allows the user to view the the entire
well bottom within 96-well plates,
zooming in for further detail as
needed. It also provides exceptional
speed for rare event, single-cell
analysis applications—generating
results up to 120 times faster than
flow cytometry.
What is SmartLux?
BioLux? SmartLux 3D?
CTL knows that the right lighting conditions are absolutely
essential for accurate results. That’s why BioSpot Analyzers
come equipped with a variety of intelligent lighting systems,
each one specifically designed to produce even illumination
and clear, distinct images.
• SmartLux is CTL’s baseline system, combining a diffuse
upper light source with a high-intensity backlighting panel.
The dual light sources can be used independently or in
tandem, allowing one to scan a wide range of substrates
and assay types.
• The BioLux system comes with an additional darkfield
illuminator for added performance. It provides remarkable
contrast, allowing the S5 Micro to generate sharp, distinct
images of colonies as small as 25 μm in diameter!
The
• SmartLux 3D system adds a coaxial fluorescent
light source to the standard SmartLux design. SmartLux
3D gives the S5 UV machine the flexibility it needs to handle
a wide range of fluorescent and visible light assays.
Cellular Technology Limited, 20521 Chagrin Blvd. Shaker Heights, OH 44122
Tel: (216) 791-5084 or (888) 791-4005
Enhanced Repeatability and Resolution
Both the S5 Micro and the S5 UV Analyzers can be equipped
with a motorized zoom lens for enhanced repeatability. This
allows precise, automatic control of the image magnification,
providing both convenience and accuracy.
Reduced costs.
Increased speed.
Increased efficiency.
Welcome to the future
of microdetection.
For further information, please contact us at (216)
791-5084 or at info@immunospot.com. You can
also visit us at www.immunospot.com.
E-mail: info@immunospot.com
Web: www.immunospot.com
GLP Support Packages
All CTL Analyzers can be used in GLP- compliant
environments. CTL supports its customers in
establishing a validated status for their devices. In
addition to offering installation qualification (IQ)
for each instrument, CTL can also assist with performance
qualification (PQ) and with 21 CFR Part 11
compliance in the customer’s environment.