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Chinese Medicine - Modern Practice (252 pages)

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Study of XS0601 on Preventing Restenosis 137<br />

(P 0.05). Taking acute gain as covariances, both XS0601 and probucol<br />

could markedly reduce angiographic late lumen loss and late lumen loss<br />

resulting from intimal hyperplasia (P < 0.05, P < O.Ol), which is similar to<br />

the morphometric analysis. LXS and HXS could also significantly increase<br />

the arterial diameter at the time of follow-up and reduce late lumen loss<br />

resulting from remodeling (P < 0.05, P < 0.01).<br />

Table 10.9. Angiographic analysis.<br />

Control Pro bucol LXS HXS<br />

Diameter 2.20 f 0.33 2.05 f 0.33 2.22 f 0.49 2.12 f 0.34<br />

(before, mm)<br />

Diameter 2.66k0.34 2.49f0.30 2.75k0.47 2.62f0.45<br />

(after, mm)<br />

Diameter 1.34 k 0.82 1.75 f 0.47 1.97 +0.51* 2.03 f 0.30*<br />

(follow-up, mm)<br />

Acute gain (mm) 0.43 f 0.17 0.51 f 0.10 0.58 k 0.03 0.55 k 0.11<br />

Late loss (mm) 1.32k0.71 0.74f0.39t 0.78k0.33t 0.59rt0.28t<br />

Values are mean k SD. No values were significantly different between groups by ANOVA<br />

(P > 0.05).<br />

‘P < 0.05, tP < 0.01, significance versus control: comparison of group means after ANOVA<br />

taking acute gain as covariance.

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