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Dr Gnant - ESMO Oral Presentation 08

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ZOL Reduced Recurrence at All Sites<br />

First event per patient, n<br />

90<br />

80<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

2<br />

10<br />

10<br />

41<br />

20<br />

No ZOL vs ZOL<br />

No ZOL ZOL<br />

(n = 904) (n = 899)<br />

DFS = Disease-free survival; ITT = Intent-to-treat; ZOL = Zoledronic acid.<br />

<strong>Gnant</strong> M, et al. Presented at: ASCO 20<strong>08</strong>. Chicago, IL. Abstract LBA4.<br />

0<br />

9<br />

6<br />

29<br />

10<br />

Death without prior recurrence<br />

Secondary malignancy<br />

Contralateral breast cancer<br />

Distant recurrence<br />

Locoregional recurrence<br />

14

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