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Diagnóstico y tratamiento de la Neuropatía amiloidótica

Diagnóstico y tratamiento de la Neuropatía amiloidótica

Diagnóstico y tratamiento de la Neuropatía amiloidótica

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Patología y Patofisiología<br />

• Depósitos amiloi<strong>de</strong>s<br />

asimétricos en endoneuro y<br />

alre<strong>de</strong>dor <strong>de</strong> vasos<br />

• Inicialmente se afectan fibras<br />

no mielinizadas (me) y se<br />

respetan fibras mielinizada<br />

• Efecto tóxico <strong>de</strong> fibril<strong>la</strong>s<br />

amiloi<strong>de</strong> sobre membrana<br />

basal <strong>de</strong> célu<strong>la</strong>s <strong>de</strong> Schwann<br />

Patterson GA, 1993<br />

Said G, 2003<br />

Said G, 2009

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