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2008 - Factores de crecimiento hematopoyético-Dr. A. Biete - GICOR

2008 - Factores de crecimiento hematopoyético-Dr. A. Biete - GICOR

2008 - Factores de crecimiento hematopoyético-Dr. A. Biete - GICOR

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Señalización EPO/EPO-R en la supervivencia<br />

hipoxica <strong>de</strong> las células cancerosas<br />

Hipoxia<br />

Muerte celular<br />

O 2 sensor<br />

(HIF-1α et al.)<br />

Genes <strong>de</strong> respuesta<br />

a la hipoxia<br />

EPO<br />

EPO-R<br />

VEGF<br />

GLUT1<br />

LDH-A<br />

NOS<br />

Tumor<br />

agresivo

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