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2008 - Factores de crecimiento hematopoyético-Dr. A. Biete - GICOR

2008 - Factores de crecimiento hematopoyético-Dr. A. Biete - GICOR

2008 - Factores de crecimiento hematopoyético-Dr. A. Biete - GICOR

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Overall, epoetin treatment shows a trend<br />

towards an improvement in survival<br />

Study<br />

Abels 1993<br />

Cascinu 1994<br />

Case 1993<br />

Cazzola 1995<br />

Coiffier 2001<br />

Dammacco 2001<br />

Del Maestro 1997<br />

Dunphy 1999<br />

Henry 1995<br />

Kurz 1997<br />

Littlewood 2001<br />

Oberhoff 1998<br />

Rose 1994<br />

Ten Bokkel Huinink 1998<br />

Thatcher 1999a<br />

Thatcher 1999b<br />

Thompson 2000<br />

Throuvalas 2000<br />

Österborg 1996<br />

Österborg 1996<br />

Österborg 2002<br />

TOTAL (OR = 0.81)<br />

Test for heterogeneity<br />

chi-square=14.49: df=18 p=0.6966<br />

Test for overall effect= –2.07 p=0.04<br />

Odds ratio (OR) (95% CI)<br />

Favours epoetin Favours control<br />

0.01 0.1 1 10 100<br />

Risk ratio<br />

Not including<br />

He<strong>de</strong>nus 2002,<br />

He<strong>de</strong>nus 2003,<br />

Kotasek 2003,<br />

Vansteenkiste 2002,<br />

Lleyland-Jones 2003,<br />

and Henke 2003<br />

Bohlius et al. Cochrane Database<br />

Syst Rev. 2004; (3): CD003407<br />

Also JNCI 2005

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